Development Level

Tbio 10 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal joint morphology 1 | 23
abnormal spleen morphology 1 | 55
brachydactyly 1 | 19
enlarged heart 1 | 210
increased body length 1 | 32
increased circulating calcium ... 1 | 34
increased prepulse inhibition 1 | 32
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
syndactyly 1 | 23

Disease

Carcinoma 7 | 11,493
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
lung cancer 5 | 4,740
Breast cancer 4 | 3,578
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
psoriasis 4 | 6,694
Sengers syndrome 3 | 18
Waldenstrons macroglobulinemia 3 | 765
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
Arthritis, Juvenile 2 | 126
Autosomal recessive predisposition 2 | 1,442
Dull intelligence 2 | 645
Intellectual disability 2 | 1,016
Juvenile arthritis 2 | 126
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Newborn respiratory distress syndrome 2 | 10
Pick disease 2 | 1,894
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Spinal Dysraphism 2 | 12
aldosterone-producing adenoma 2 | 665
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal color vision 1 | 31
Abnormal vision 1 | 52
Abnormality of the ribs 1 | 32
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Anteriorly placed anus 1 | 7
Asphyxiating thoracic dystrophy 1 | 44
Astigmatism 1 | 54
Barrett's esophagus 1 | 182
Brachydactyly 1 | 156
Chemical and Drug Induced Liver Injury 1 | 195
Choanal Atresia 1 | 42
Choanal stenosis 1 | 11
Cholera 1 | 34
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Cone dystrophy 1 | 71
Cone/cone-rod dystrophy 1 | 20
Cutis marmorata 1 | 32
Decreased visual acuity, progressive 1 | 36
Dental abnormalities 1 | 60
Difficulties with night vision 1 | 87
Flexion contracture - elbow 1 | 32
High-grade hypermetropia 1 | 24
Hip joint varus deformity - observation 1 | 24
Joint stiffness 1 | 84
Lordosis 1 | 54
Loss of peripheral vision 1 | 5
Malocclusion 1 | 57
Microglossia 1 | 10
Moderate mental retardation (I.Q. 35-49) 1 | 28
Narcolepsy 1 | 72
Penile hypospadias 1 | 106
Periventricular nodular heterotopia 1 | 30
Photodysphoria 1 | 121
Photophobia 1 | 121
Pigmentary iris degeneration 1 | 20
Platyspondyly 1 | 56
Poor speech 1 | 37
Postnatal growth retardation 1 | 57
Problems speaking 1 | 37
Progressive visual loss 1 | 36
Recurrent otitis media 1 | 42
Relative macrocephaly 1 | 12
Respiratory Distress Syndrome, Adult 1 | 40
Rhizomelia 1 | 25
Short to absent middle phalanges 1 | 5
Small tongue 1 | 10
Tooth Abnormalities 1 | 69
Tunnel visual field constriction 1 | 5
X-linked cerebral adrenoleukodystrophy 1 | 116
cone-rod dystrophy 1 | 59
facioscapulohumeral dystrophy 1 | 288
nutritional deficiency disease 1 | 9
sarcoidosis 1 | 370

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Enzyme 9 | 4,145
Kinase 4 | 634

WikiPathways Pathway

Kennedy pathway from Sphingoli... 13 | 13
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Choline-phosphate cytidylyltransferase B PCYT1B Tbio Enzyme -1.46937 28.8 40
Cholinephosphotransferase 1 CHPT1 Tbio Enzyme -1.42313 23.5 80
Ethanolamine kinase 1 ETNK1 Tbio Kinase -1.59702 38.8 152
Choline-phosphate cytidylyltransferase A PCYT1A Tbio Enzyme -2.39713 242.7 191
Phosphatidylserine synthase 2 PTDSS2 Tbio Enzyme -0.81845 6.34 84
Phosphatidylserine synthase 1 PTDSS1 Tbio Enzyme -1.93971 87.1 109
Phosphatidylethanolamine N-methyltransferase PEMT Tbio Enzyme -1.90213 89.9 149
Choline kinase alpha CHKA Tchem Kinase -2.47227 275.1 159
Ethanolamine kinase 2 ETNK2 Tdark Kinase -0.68956 4.93 132
Choline/ethanolaminephosphotransferase 1 CEPT1 Tbio Enzyme -1.65915 46.8 82