Development Level

Tbio 13 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

male infertility 2 | 123
preweaning lethality, complete... 2 | 979
abnormal maxilla morphology 1 | 17
abnormal tooth morphology 1 | 24
cyanosis 1 | 7
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
increased body length 1 | 32
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 14 | 11,493
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
Kidney cancer 7 | 2,613
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
psoriasis 6 | 6,694
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
dermatomyositis 4 | 966
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
Cancer 3 | 2,499
Multiple myeloma 3 | 1,332
Waldenstrons macroglobulinemia 3 | 765
Weaver syndrome 3 | 7
astrocytic glioma 3 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398
Congenital pes cavus 2 | 88
Endometrial Neoplasms 2 | 55
Liver cancer 2 | 604
Nerve Sheath Neoplasms 2 | 5
Nerve Sheath Tumors 2 | 5
Neurilemmoma 2 | 23
Pick disease 2 | 1,894
Retinoblastoma 2 | 19
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormal lower motor neuron morphology 1 | 6
Abnormality of the fingernails 1 | 51
Advanced bone age 1 | 35
Apraxia 1 | 26
Ataxia telangiectasia 1 | 34
Ataxia, Appendicular 1 | 25
Autism Spectrum Disorders 1 | 75
Axonal degeneration 1 | 7
Branchiootic syndrome 1 | 12
Broad feet 1 | 19
Broad thumbs 1 | 28
Calcaneovalgus deformity 1 | 8
Calcinosis 1 | 70
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 15
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Decreased motor NCV 1 | 22
Deep philtrum 1 | 21
Depressed philtrum 1 | 21
Diffuse large B-cell lymphoma 1 | 39
Dilation of lateral ventricles 1 | 4
Endometrial stromal nodule 1 | 11
Endometrial stromal sarcoma 1 | 15
Fine hair 1 | 42
Glioma 1 | 74
Hoarseness 1 | 31
Hyperkyphosis 1 | 111
Hypoplastic toenails 1 | 22
Juvenile Myelomonocytic Leukemia 1 | 21
Kyphosis deformity of spine 1 | 114
Large hand 1 | 18
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 8
Leukemia, Myelomonocytic, Juvenile 1 | 20
Lymphoma, Large B-Cell, Diffuse 1 | 34
Metatarsus Varus 1 | 24
Myelodysplastic Syndromes 1 | 26
Nance-Horan syndrome 1 | 25
Nephroblastoma 1 | 51
Neurofibroma 1 | 8
Neurofibromatosis 1 | 40
Nystagmus, End-Position 1 | 12
Peripheral Neuropathy 1 | 134
Polyneuropathy 1 | 64
Pyramidal sign 1 | 29
Round face 1 | 45
Round, full face 1 | 45
Short ribs 1 | 30
Small Cell Lung Carcinoma 1 | 41
Small cell carcinoma of lung 1 | 45
Spastic Ataxia 1 | 18
Specific language impairment 1 | 34
Spina bifida occulta 1 | 19
Tall stature 1 | 34
Toeing-in 1 | 24
Waardenburg's syndrome 1 | 17

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 9 | 12,091
Epigenetic 3 | 242
Enzyme 2 | 4,145
Kinase 1 | 634
TF/Epigenetic 1 | 38

WikiPathways Pathway

Interactome of polycomb repres... 16 | 16
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid hormone receptor-associated protein 3 THRAP3 Tbio Non-IDG -0.87769 8.81 136
Bcl-2-associated transcription factor 1 BCLAF1 Tbio Non-IDG -2.29538 190.0 210
MORC family CW-type zinc finger protein 3 MORC3 Tbio Non-IDG -1.61241 36.6 61
Protein Jumonji JARID2 Tbio TF/Epigenetic -1.80136 65.3 135
Histone-lysine N-methyltransferase EZH1 EZH1 Tchem Epigenetic -1.26072 14.8 291
Serine/threonine-protein kinase 38 STK38 Tbio Kinase -1.32086 23.2 359
Tripartite motif-containing protein 35 TRIM35 Tbio Non-IDG -1.51277 31.9 226
Zinc finger protein AEBP2 AEBP2 Tbio Non-IDG -1.04176 10.9 122
Histone-binding protein RBBP4 RBBP4 Tbio Non-IDG -1.71209 53.9 310
Polycomb protein EED EED Tchem Non-IDG -2.23450 157.4 278