Development Level

Tbio 47 | 10,625
Tchem 37 | 1,890
Tclin 15 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 4 | 633
decreased body weight 3 | 174
abnormal behavior 2 | 226
abnormal retina morphology 2 | 100
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 195
increased hematocrit 2 | 36
preweaning lethality, incomple... 2 | 260
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal lens morphology 1 | 73
abnormal respiratory quotient 1 | 9
cataract 1 | 26
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased leukocyte cell numbe... 1 | 54
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
hydrops fetalis 1 | 22
hyperactivity 1 | 108
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased leukocyte cell numbe... 1 | 37
increased monocyte cell number 1 | 27
increased vertical activity 1 | 18
thrombocytosis 1 | 23
tremors 1 | 34

Disease

osteosarcoma 59 | 7,933
ovarian cancer 54 | 8,484
Cancer 53 | 2,346
glioblastoma 47 | 5,572
psoriasis 38 | 6,685
medulloblastoma, large-cell 35 | 6,234
lung cancer 31 | 4,466
atypical teratoid / rhabdoid tumor 30 | 4,369
pilocytic astrocytoma 28 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,289
invasive ductal carcinoma 27 | 2,950
lung carcinoma 25 | 2,844
pediatric high grade glioma 25 | 2,712
Breast cancer 24 | 3,094
malignant mesothelioma 24 | 3,162
non-small cell lung cancer 24 | 2,798
pancreatic cancer 24 | 2,300
Carcinoma 23 | 2,147
ependymoma 23 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,988
tuberculosis 21 | 1,557
diabetes mellitus 20 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
interstitial cystitis 18 | 2,299
oligodendroglioma 18 | 2,849
colon cancer 17 | 1,475
cystic fibrosis 17 | 1,665
lung adenocarcinoma 17 | 2,713
ulcerative colitis 17 | 2,087
group 3 medulloblastoma 16 | 2,254
subependymal giant cell astrocytoma 16 | 2,287
astrocytoma 15 | 1,493
astrocytic glioma 14 | 2,241
medulloblastoma 14 | 1,524
primary pancreatic ductal adenocarcinoma 14 | 1,271
primitive neuroectodermal tumor 14 | 3,031
group 4 medulloblastoma 13 | 1,875
juvenile dermatomyositis 12 | 1,189
Multiple myeloma 11 | 1,327
adult high grade glioma 11 | 2,148
breast carcinoma 11 | 1,614
ductal carcinoma in situ 11 | 1,745
posterior fossa group A ependymoma 11 | 1,511
Duchenne muscular dystrophy 10 | 602
Intellectual disability 10 | 573
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
pituitary cancer 10 | 1,972
Pick disease 9 | 1,893
dermatomyositis 9 | 933
Cardiomyopathy 8 | 110
Gliosis 8 | 16
Mammary Neoplasms 8 | 410
Neoplasm Invasiveness 8 | 127
Prostatic Neoplasms 8 | 471
Vascular disease 8 | 281
Arthritis 7 | 248
Down syndrome 7 | 548
Endometriosis 7 | 535
Heart disease 7 | 279
IGA Glomerulonephritis 7 | 454
Multiple Sclerosis 7 | 498
Noonan Syndrome 7 | 33
Rheumatoid Arthritis 7 | 1,160
Schizophrenia 7 | 501
Waldenstrons macroglobulinemia 7 | 765
adrenocortical carcinoma 7 | 1,427
cutaneous lupus erythematosus 7 | 1,056
non-small cell lung carcinoma 7 | 413
Asthma 6 | 349
Atopic dermatitis 6 | 944
Cardiomyopathies 6 | 90
Leukocyte adhesion deficiency 6 | 15
Lung Neoplasms 6 | 171
Melanoma 6 | 261
Osteoporosis 6 | 257
Squamous cell carcinoma 6 | 94
Stomach Neoplasms 6 | 282
acute myeloid leukemia 6 | 780
acute quadriplegic myopathy 6 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
gastric carcinoma 6 | 832
nasopharyngeal carcinoma 6 | 1,056
pancreatic carcinoma 6 | 567
primary Sjogren syndrome 6 | 789
spina bifida 6 | 1,064
Acute Promyelocytic Leukemia 5 | 31
COPD 5 | 113
Cardiomegaly 5 | 66
Glaucoma 5 | 134
Hyperalgesia 5 | 71
Kidney disease 5 | 396
LEOPARD Syndrome 5 | 20
Myopathy 5 | 128
Neoplasm Metastasis 5 | 138
Obesity 5 | 616
atypical teratoid/rhabdoid tumor 5 | 1,095
fibroadenoma 5 | 557
hereditary spastic paraplegia 5 | 313
posterior fossa group B ependymoma 5 | 1,530
tuberculosis and treatment for 6 months 5 | 686

Tissue

Blood and immune system 100 | 17,995
Cardiovascular System 100 | 17,958
Digestive Tract 100 | 18,473
Endocrine System 100 | 18,512
Female tissues 100 | 18,647
Liver and Pancreas 100 | 18,136
Male tissues 100 | 17,969
Nervous System 100 | 18,561
Respiratory system 100 | 17,484
Skin and soft tissues 100 | 18,115
Urinary Tract 100 | 18,444

Target Family

Non-IDG 59 | 11,971
Kinase 31 | 634
Enzyme 9 | 4,146
GPCR 1 | 406

WikiPathways Pathway

Integrin-mediated Cell Adhesio... 100 | 100
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calpain-5 CAPN5 Tbio Non-IDG -1.66912 47.3 128
Selenoprotein P SELENOP Tbio Non-IDG -2.42408 315.2 94
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -2.99303 933.5 424
Integrin alpha-4 ITGA4 Tclin Non-IDG -2.47245 289.0 895
Integrin alpha-6 ITGA6 Tchem Non-IDG -2.25486 168.8 756
Integrin alpha-M ITGAM Tchem Non-IDG -3.58843 3795.9 1805
3-phosphoinositide-dependent protein kinase 1 PDPK1 Tchem Kinase -2.24871 191.5 579
Rho-associated protein kinase 2 ROCK2 Tclin Kinase -2.39656 248.3 472
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.78634 57.0 688
Ras-related protein Rap-1A RAP1A Tchem Enzyme -2.40521 288.3 256