Development Level

Tbio 13 | 10,625
Tchem 11 | 1,890
Tclin 8 | 602

IMPC Term

decreased body length 2 | 108
preweaning lethality, complete... 2 | 633
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 23
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating amylase ... 1 | 24
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased lean body mass 1 | 195
decreased macrophage cell numb... 1 | 4
decreased mean corpuscular hem... 1 | 19
decreased thermal nociceptive ... 1 | 4
enlarged epididymis 1 | 27
enlarged heart 1 | 111
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased leukocyte cell numbe... 1 | 37
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
increased thermal nociceptive ... 1 | 9
male infertility 1 | 62

Disease

ovarian cancer 20 | 8,484
Cancer 18 | 2,346
osteosarcoma 16 | 7,933
Multiple myeloma 15 | 1,327
glioblastoma 12 | 5,572
lung cancer 12 | 4,466
psoriasis 12 | 6,685
medulloblastoma, large-cell 11 | 6,234
atypical teratoid / rhabdoid tumor 10 | 4,369
adult high grade glioma 9 | 2,148
primitive neuroectodermal tumor 9 | 3,031
subependymal giant cell astrocytoma 9 | 2,287
Peripheral T-cell lymphoma 8 | 24
Primary cutaneous T-cell lymphoma 8 | 24
ependymoma 8 | 2,514
malignant mesothelioma 8 | 3,162
medulloblastoma 8 | 1,524
Carcinoma 7 | 2,147
Breast cancer 6 | 3,094
Pick disease 6 | 1,893
astrocytoma 6 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
oligodendroglioma 6 | 2,849
pilocytic astrocytoma 5 | 3,086
sonic hedgehog group medulloblastoma 5 | 1,482
ulcerative colitis 5 | 2,087
Intellectual disability 4 | 573
Rheumatoid Arthritis 4 | 1,160
Schizophrenia 4 | 501
Wolf-Hirschhorn syndrome 4 | 32
acute myeloid leukemia 4 | 780
acute quadriplegic myopathy 4 | 1,157
astrocytic glioma 4 | 2,241
lung adenocarcinoma 4 | 2,713
primary pancreatic ductal adenocarcinoma 4 | 1,271
tuberculosis 4 | 1,557
Asthma 3 | 349
Bladder Neoplasm 3 | 109
Brain Ischemia 3 | 87
Crohn's disease 3 | 304
Familial primary pulmonary hypertension 3 | 3
Mammary Neoplasms 3 | 410
Neoplastic Cell Transformation 3 | 81
Waldenstrons macroglobulinemia 3 | 765
colon cancer 3 | 1,475
diabetes mellitus 3 | 1,663
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
invasive ductal carcinoma 3 | 2,950
lung carcinoma 3 | 2,844
non primary Sjogren syndrome sicca 3 | 840
non-small cell lung cancer 3 | 2,798
pediatric high grade glioma 3 | 2,712
posterior fossa group A ependymoma 3 | 1,511
Acquired immunodeficiency syndrome 2 | 164
Adenoid Cystic Carcinoma 2 | 99
Arthritis 2 | 248
Carcinoma, Transitional Cell 2 | 31
Cocaine-Related Disorders 2 | 88
Colonic Neoplasms 2 | 126
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Endometriosis 2 | 535
Gaucher disease type 3 2 | 76
Heart Diseases 2 | 42
Heat Stroke 2 | 12
Hepatolenticular Degeneration 2 | 24
Inflammatory bowel disease 2 | 142
Kidney Failure, Chronic 2 | 45
Kidney cancer 2 | 118
Left Ventricular Hypertrophy 2 | 24
Mantle cell lymphoma 2 | 18
Melanoma 2 | 261
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 127
Obesity 2 | 616
Osteoporosis 2 | 257
Progressive multifocal leukoencephalopathy 2 | 24
Prostatic Neoplasms 2 | 471
Rubinstein-Taybi syndrome 2 | 11
Skin Neoplasms 2 | 49
Small cell carcinoma of lung 2 | 45
Squamous cell carcinoma 2 | 94
Squamous cell carcinoma of esophagus 2 | 82
adrenocortical carcinoma 2 | 1,427
atypical teratoid/rhabdoid tumor 2 | 1,095
cystic fibrosis 2 | 1,665
gastric carcinoma 2 | 832
group 4 medulloblastoma 2 | 1,875
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Alcohol dependence 1 | 107
Brain disease 1 | 83
Diabetes Mellitus, Experimental 1 | 106
Mastitis 1 | 48
Osteopetrosis 1 | 40
Renal Cell Carcinoma 1 | 199
Stevens-Johnson syndrome 1 | 78
non-inflammatory breast cancer 1 | 208

Tissue

Blood and immune system 32 | 17,995
Cardiovascular System 32 | 17,958
Digestive Tract 32 | 18,473
Endocrine System 32 | 18,512
Female tissues 32 | 18,647
Liver and Pancreas 32 | 18,136
Male tissues 32 | 17,969
Nervous System 32 | 18,561
Respiratory system 32 | 17,484
Skin and soft tissues 32 | 18,115
Urinary Tract 32 | 18,444

Target Family

Non-IDG 11 | 11,971
Epigenetic 10 | 242
Transcription Factor 7 | 1,400
Enzyme 3 | 4,146
Kinase 1 | 634

WikiPathways Pathway

Initiation of transcription an... 32 | 32
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Protein HEXIM1 HEXIM1 Tchem Non-IDG -1.77975 61.2 311
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA Tchem Enzyme -2.95943 932.4 290
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.75838 5701.8 723
Nuclear factor of activated T-cells, cytoplasmic 3 NFATC3 Tbio Transcription Factor -1.99681 101.3 183
Nuclear factor of activated T-cells, cytoplasmic 4 NFATC4 Tbio Transcription Factor -1.90714 83.3 340
Transcription elongation factor SPT4 SUPT4H1 Tbio Non-IDG -1.62598 41.7 63
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.33405 229.4 425
Histone deacetylase 1 HDAC1 Tclin Epigenetic -2.97422 866.1 1107