Development Level

Tbio 9 | 11,445
Tclin 7 | 613
Tchem 4 | 1,598

IMPC Phenotype

abnormal sleep behavior 2 | 70
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
decreased bone mineral density 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
female infertility 1 | 60
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56

Disease

Cancer 18 | 2,499
Carcinoma 17 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 12 | 8,520
medulloblastoma, large-cell 10 | 6,241
psoriasis 10 | 6,694
adrenocortical carcinoma 9 | 1,428
lung cancer 9 | 4,740
malignant mesothelioma 9 | 3,232
Breast Neoplasms 8 | 445
Breast cancer 8 | 3,578
Mammary Neoplasms 8 | 425
glioblastoma 8 | 5,792
non-small cell lung cancer 8 | 2,890
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pancreatic cancer 7 | 2,398
Astrocytoma, Pilocytic 6 | 3,081
Gastrointestinal stromal tumor 6 | 62
Kidney cancer 6 | 2,613
Liver Cirrhosis, Experimental 6 | 769
astrocytic glioma 6 | 2,597
group 3 medulloblastoma 6 | 4,104
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Immune system cancer 5 | 140
Leukemia, Myelocytic, Acute 5 | 120
Lymphoid leukemia 5 | 160
Neoplasm Metastasis 5 | 168
Pancreatic Neuroendocrine Tumor 5 | 45
Renal Cell Carcinoma 5 | 214
Sarcoma of soft tissue 5 | 11
Stomach Neoplasms 5 | 300
acute myeloid leukemia 5 | 783
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung carcinoma 5 | 2,843
non-small cell lung carcinoma 5 | 317
Bipolar Disorder 4 | 666
Carcinoma, Hepatocellular 4 | 228
Carcinoma, Non-Small-Cell Lung 4 | 107
Chronic eosinophilic leukemia 4 | 11
Fatigue 4 | 182
Hypereosinophilic syndrome 4 | 71
Idiopathic hypereosinophilic syndrome 4 | 10
Leukemia, Myeloid, Acute 4 | 105
Liver carcinoma 4 | 240
Multiple Sclerosis 4 | 540
Myeloproliferative disease 4 | 16
Neoplasms 4 | 63
Ovarian Neoplasms 4 | 102
Philadelphia chromosome-positive acute lymphoblastic leukemia 4 | 47
Rheumatoid arthritis 4 | 1,191
ovarian neoplasm 4 | 99
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
Adenoma 3 | 167
Arthritis, Rheumatoid 3 | 174
Carcinoma of thyroid 3 | 17
Chemical and Drug Induced Liver Injury 3 | 195
Chronic Myelocytic Leukemia Accelerated Phase 3 | 59
Decreased platelet count 3 | 111
Depressive disorder 3 | 409
Dermatofibrosarcoma protuberans 3 | 15
Diffuse large B-cell lymphoma 3 | 39
Disease Progression 3 | 136
Duchenne muscular dystrophy 3 | 601
Eosinophilia 3 | 28
Follicular thyroid carcinoma 3 | 14
Hamman-Rich syndrome 3 | 34
Isolated cases 3 | 72
Liver cell carcinoma 3 | 15
Liver neoplasms 3 | 130
Lung Neoplasms 3 | 232
MYELODYSPLASTIC SYNDROME 3 | 53
Mastocytosis 3 | 27
Melanoma 3 | 711
Multiple myeloma 3 | 1,332
Nausea and vomiting 3 | 97
Papillary thyroid carcinoma 3 | 43
Polycythemia vera 3 | 27
Precursor Cell Lymphoblastic Leukemia Lymphoma 3 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 | 49
Prostatic Neoplasms 3 | 495
Skin cancer 3 | 469
Somatic mutation 3 | 61
Thrombocytopenia 3 | 197
acute lymphocytic leukemia 3 | 33
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
medulloblastoma 3 | 720
pituitary cancer 3 | 1,972
urothelial carcinoma 3 | 318

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Kinase 8 | 634
Non-IDG 4 | 12,091
Enzyme 3 | 4,145
Transcription Factor 3 | 1,400
Transporter 2 | 473

WikiPathways Pathway

Imatinib and Chronic Myeloid L... 20 | 20
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
GRB2-associated-binding protein 2 GAB2 Tbio Non-IDG -2.08460 139.8 494
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase NOP2 Tbio Enzyme -1.50027 29.5 69
Breakpoint cluster region protein BCR Tclin Non-IDG -2.99605 934.2 437
Multidrug resistance protein 1 ABCB1 Tchem Transporter -3.61827 4039.4 875
Protein lyl-1 LYL1 Tbio Transcription Factor -1.52052 35.3 126
Serine/threonine-protein kinase pim-2 PIM2 Tchem Kinase -2.28237 187.3 304
Macrophage colony-stimulating factor 1 receptor CSF1R Tclin Kinase -3.19109 1432.9 1169