Development Level

Tbio 15 | 11,445
Tchem 9 | 1,598
Tclin 6 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal skin condition 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
embryonic lethality prior to t... 1 | 278
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 499

Disease

Cancer 18 | 2,499
Carcinoma 18 | 11,493
ovarian cancer 17 | 8,520
psoriasis 17 | 6,694
glioblastoma 16 | 5,792
osteosarcoma 15 | 7,950
atypical teratoid / rhabdoid tumor 11 | 5,112
lung cancer 11 | 4,740
Arthritis 10 | 290
medulloblastoma, large-cell 10 | 6,241
Brain Ischemia 9 | 110
Schizophrenia 9 | 1,160
astrocytoma 9 | 1,146
Asthma 8 | 385
Prostatic Neoplasms 8 | 495
diabetes mellitus 8 | 1,728
ependymoma 8 | 4,679
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
Obesity 7 | 678
group 3 medulloblastoma 7 | 4,104
pituitary cancer 7 | 1,972
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Breast cancer 6 | 3,578
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Candidiasis 5 | 55
Inflammatory bowel disease 5 | 151
Multiple Sclerosis 5 | 540
Multiple myeloma 5 | 1,332
Rheumatoid arthritis 5 | 1,191
Vascular disease 5 | 319
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
pancreatic cancer 5 | 2,398
Acquired scoliosis 4 | 281
Anemia 4 | 365
Autosomal recessive predisposition 4 | 1,442
Candidiasis, Chronic Mucocutaneous 4 | 11
Carcinoma, Squamous Cell 4 | 110
Cardiomyopathies 4 | 110
Cell Transformation, Neoplastic 4 | 97
Cholestasis, Extrahepatic 4 | 25
Crohn's disease 4 | 321
Curvature of spine 4 | 282
Depressive disorder 4 | 409
Dermatitis 4 | 157
Disease Models, Animal 4 | 155
Exanthema 4 | 43
Hyperglycemia 4 | 137
Hyperkeratosis 4 | 50
Hypersensitivity reaction type II disease 4 | 253
Inflammation 4 | 120
Kidney disease 4 | 430
Liver Neoplasms, Experimental 4 | 59
Lung Neoplasms 4 | 232
Neoplasm Invasiveness 4 | 161
Neoplasm Metastasis 4 | 168
Neoplastic Cell Transformation 4 | 89
Ovarian Neoplasms 4 | 102
Papule 4 | 43
Psoriatic arthritis 4 | 86
Short stature 4 | 531
Skin Ulcer 4 | 48
Squamous cell carcinoma 4 | 129
Stomach Neoplasms 4 | 300
acute quadriplegic myopathy 4 | 1,158
breast carcinoma 4 | 1,638
chronic mucocutaneous candidiasis 4 | 7
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
ovarian neoplasm 4 | 99
pediatric high grade glioma 4 | 1,064
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Byzanthine arch palate 3 | 194
Colonic Neoplasms 3 | 142
Fever 3 | 138
Heart disease 3 | 306
Hypereosinophilic syndrome 3 | 71
Hypertension 3 | 396
Infantile onset 3 | 238
Liver Cirrhosis, Experimental 3 | 769
Lung disease 3 | 142
Mental Depression 3 | 333
Mood Disorders 3 | 184
Parkinson's disease 3 | 392
Pick disease 3 | 1,894
Pneumonia 3 | 174
Toxic encephalopathy 3 | 141
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Blood and immune system 31 | 16,909
Urinary Tract 31 | 16,678
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Liver and Pancreas 30 | 16,750
Female tissues 29 | 17,400
Male tissues 29 | 17,142
Skin and soft tissues 29 | 17,230
Cardiovascular System 28 | 15,192
Respiratory system 28 | 16,393
Nervous System 27 | 16,725

Target Family

Non-IDG 15 | 12,091
Kinase 10 | 634
Transcription Factor 6 | 1,400

WikiPathways Pathway

IL17 signaling pathway 31 | 31
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Adapter protein CIKS TRAF3IP2 Tbio Non-IDG -1.81845 71.6 360
CCAAT/enhancer-binding protein delta CEBPD Tbio Transcription Factor -2.49029 299.9 179
Interleukin-17D IL17D Tbio Non-IDG -1.30260 17.4 327
Interleukin-17C IL17C Tbio Non-IDG -2.09462 124.6 192
Interleukin-17 receptor C IL17RC Tclin Non-IDG -1.54212 27.9 233
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Interleukin-17B IL17B Tbio Non-IDG -1.18085 14.9 290
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Interleukin-17F IL17F Tbio Non-IDG -2.59592 347.9 586