Development Level

Tbio 10 | 11,651
Tchem 9 | 1,388
Tclin 5 | 612

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal vibrissa morphology 1 | 25
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating sodium l... 1 | 22
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating insulin ... 1 | 3
increased erythrocyte cell num... 1 | 39
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
tremors 1 | 39

Disease

Cancer 20 | 2,499
lung cancer 19 | 4,740
psoriasis 16 | 6,694
tuberculosis 16 | 2,010
Carcinoma 15 | 11,493
Asthma 14 | 385
Astrocytoma, Pilocytic 14 | 3,081
diabetes mellitus 14 | 1,728
glioblastoma 14 | 5,792
interstitial cystitis 14 | 2,312
ovarian cancer 14 | 8,520
ulcerative colitis 14 | 1,819
Schizophrenia 13 | 1,160
cutaneous lupus erythematosus 13 | 1,057
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
Arthritis 12 | 290
invasive ductal carcinoma 12 | 2,951
Atherosclerosis 11 | 291
Coronary artery disease 11 | 268
Inflammatory bowel disease 11 | 151
Kidney disease 11 | 430
Hypersensitivity reaction type II disease 10 | 253
Inflammation 10 | 120
Obesity 10 | 678
adult high grade glioma 10 | 3,801
pancreatic cancer 10 | 2,398
Breast cancer 9 | 3,578
Endometriosis 9 | 540
Hypertension 9 | 396
Liver Cirrhosis, Experimental 9 | 769
Liver disease 9 | 237
Lung disease 9 | 142
Multiple Sclerosis 9 | 540
Pneumonia 9 | 174
Rheumatoid arthritis 9 | 1,191
cystic fibrosis 9 | 1,696
ependymoma 9 | 4,679
medulloblastoma, large-cell 9 | 6,241
Allergic hypersensitivity disease 8 | 126
Cerebrovascular disease 8 | 238
Dermatitis 8 | 157
Heart disease 8 | 306
Peritonitis 8 | 43
atypical teratoid / rhabdoid tumor 8 | 5,112
lung adenocarcinoma 8 | 2,716
nasopharyngeal carcinoma 8 | 1,058
non-small cell lung cancer 8 | 2,890
osteosarcoma 8 | 7,950
Bipolar Disorder 7 | 666
Brain Ischemia 7 | 110
Meningitis 7 | 67
Reperfusion Injury 7 | 86
periodontitis 7 | 293
Arthritis, Rheumatoid 6 | 174
Brain Injuries 6 | 65
Calcinosis 6 | 70
Colonic Neoplasms 6 | 142
Diabetes Mellitus, Experimental 6 | 108
Hypertensive disease 6 | 292
Malaria 6 | 160
Pulmonary Fibrosis 6 | 106
Vasculitis 6 | 80
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 807
head and neck cancer 6 | 271
hepatocellular carcinoma 6 | 547
juvenile dermatomyositis 6 | 1,187
mucosa-associated lymphoid tissue lymphoma 6 | 484
primary pancreatic ductal adenocarcinoma 6 | 1,109
subependymal giant cell astrocytoma 6 | 2,287
Alzheimer's disease 5 | 658
Atopic dermatitis 5 | 952
Cerebrovascular accident 5 | 63
Chemical and Drug Induced Liver Injury 5 | 195
Cholestasis, Extrahepatic 5 | 25
Disease Models, Animal 5 | 155
Heart valve disease 5 | 39
Hypersensitivity 5 | 63
Influenza 5 | 142
Leishmaniasis 5 | 47
Myocardial Infarction 5 | 151
Neoplasm Invasiveness 5 | 161
Stomach Neoplasms 5 | 300
Urticaria 5 | 67
acute quadriplegic myopathy 5 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pituitary cancer 5 | 1,972
Allergic rhinitis 4 | 95
Cholestasis 4 | 155
Collagen disease 4 | 27
Eye disease 4 | 62
Hypereosinophilic syndrome 4 | 71
Kidney cancer 4 | 2,613
Prostatic Neoplasms 4 | 495
Vascular disease 4 | 319
colon cancer 4 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic carcinoma 4 | 562

Tissue

Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678
Blood and immune system 23 | 16,909
Female tissues 23 | 17,400
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 14 | 12,091
Enzyme 5 | 4,145
GPCR 2 | 408
Kinase 2 | 634
Transcription Factor 1 | 1,400

WikiPathways Pathway

IL1 and megakaryocytes in obes... 24 | 24
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Interleukin-1 receptor type 1 IL1R1 Tclin Non-IDG -2.68139 387.6 620
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
Metalloproteinase inhibitor 1 TIMP1 Tbio Enzyme -3.57247 3714.8 810
Interferon gamma IFNG Tbio Non-IDG -3.90985 5727.4 2248
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.58807 348.8 804
C-C chemokine receptor type 3 CCR3 Tchem GPCR -2.62143 397.9 554
High affinity immunoglobulin epsilon receptor subunit alpha FCER1A Tbio Non-IDG -2.31573 208.4 438
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519