Development Level

Tbio 12 | 10,625
Tchem 4 | 1,890

IMPC Term

abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal eye morphology 1 | 38
abnormal retina morphology 1 | 100
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
decreased prepulse inhibition 1 | 52
increased B cell number 1 | 23
increased T cell number 1 | 15
increased circulating alkaline... 1 | 119
increased lactate dehydrogenas... 1 | 3

Disease

Cancer 12 | 2,346
osteosarcoma 12 | 7,933
medulloblastoma, large-cell 10 | 6,234
ovarian cancer 10 | 8,484
glioblastoma 9 | 5,572
psoriasis 9 | 6,685
lung cancer 7 | 4,466
malignant mesothelioma 7 | 3,162
adrenocortical carcinoma 6 | 1,427
astrocytoma 5 | 1,493
atypical teratoid / rhabdoid tumor 5 | 4,369
oligodendroglioma 5 | 2,849
pancreatic cancer 5 | 2,300
pilocytic astrocytoma 5 | 3,086
posterior fossa group A ependymoma 5 | 1,511
Rheumatoid Arthritis 4 | 1,160
group 4 medulloblastoma 4 | 1,875
interstitial cystitis 4 | 2,299
juvenile dermatomyositis 4 | 1,189
lung adenocarcinoma 4 | 2,713
non-small cell lung cancer 4 | 2,798
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 789
primary pancreatic ductal adenocarcinoma 4 | 1,271
Breast cancer 3 | 3,094
Carcinoma 3 | 2,147
Chronic Lymphocytic Leukemia 3 | 242
Liver carcinoma 3 | 217
Mammary Neoplasms 3 | 410
Mammary Neoplasms, Experimental 3 | 150
acute quadriplegic myopathy 3 | 1,157
astrocytic glioma 3 | 2,241
cystic fibrosis 3 | 1,665
ependymoma 3 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
pediatric high grade glioma 3 | 2,712
primitive neuroectodermal tumor 3 | 3,031
sonic hedgehog group medulloblastoma 3 | 1,482
ulcerative colitis 3 | 2,087
Animal Mammary Neoplasms 2 | 136
Bladder Neoplasm 2 | 109
Diabetes Mellitus, Experimental 2 | 106
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Endometriosis 2 | 535
Kidney Failure, Chronic 2 | 45
Kidney disease 2 | 396
Myocardial Ischemia 2 | 169
Nephrogenic adenoma 2 | 10
Nephrogenic adenoma of urinary bladder 2 | 2
Obesity 2 | 616
Pick disease 2 | 1,893
Precursor Cell Lymphoblastic Leukemia Lymphoma 2 | 42
Retinoblastoma 2 | 14
Small cell carcinoma of lung 2 | 45
Thyroid Diseases 2 | 12
Urinary bladder cancer 2 | 31
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
atypical teratoid/rhabdoid tumor 2 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
colon cancer 2 | 1,475
dermatomyositis 2 | 933
diabetes mellitus 2 | 1,663
gastric cancer 2 | 430
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
invasive ductal carcinoma 2 | 2,950
nephrosclerosis 2 | 329
ovarian neoplasm 2 | 97
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 6 months 2 | 686
Adenoma 1 | 165
Aniridia 1 | 26
Atherosclerosis 1 | 275
Brain Ischemia 1 | 87
Colonic Neoplasms 1 | 126
Colorectal Neoplasms 1 | 217
Dermatologic disorders 1 | 65
Disease Progression 1 | 125
Hypothyroidism 1 | 89
IGA Glomerulonephritis 1 | 454
Lipid metabolism disorder 1 | 102
Lung Neoplasms 1 | 171
Malignant neoplasm of urinary bladder 1 | 16
Metabolic syndrome X 1 | 155
Microphthalmia 1 | 78
Myopathy 1 | 128
Pancreatic Neoplasm 1 | 79
Parkinson's disease 1 | 364
Peripheral Neuropathy 1 | 303
Reperfusion Injury 1 | 84
X-linked cerebral adrenoleukodystrophy 1 | 115
adrenocortical adenoma 1 | 134
facioscapulohumeral dystrophy 1 | 286
nervous system disorder 1 | 53
non-small cell lung carcinoma 1 | 413
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 16 | 17,995
Cardiovascular System 16 | 17,958
Digestive Tract 16 | 18,473
Endocrine System 16 | 18,512
Female tissues 16 | 18,647
Liver and Pancreas 16 | 18,136
Male tissues 16 | 17,969
Nervous System 16 | 18,561
Skin and soft tissues 16 | 18,115
Urinary Tract 16 | 18,444
Respiratory system 15 | 17,484

Target Family

Transcription Factor 11 | 1,400
Non-IDG 4 | 11,971
Kinase 1 | 634

WikiPathways Pathway

ID signaling pathway 16 | 16
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.65970 471.8 306
ETS domain-containing protein Elk-3 ELK3 Tbio Transcription Factor -0.06070 0.86 186
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -0.97785 9.77 84
Myoblast determination protein 1 MYOD1 Tbio Transcription Factor -3.13423 1281.5 563
Retinoblastoma-like protein 1 RBL1 Tbio Non-IDG -2.61434 376.7 290
Sterol regulatory element-binding protein 1 SREBF1 Tbio Transcription Factor -3.04271 1134.6 386
G1/S-specific cyclin-E1 CCNE1 Tchem Non-IDG -2.40805 239.2 741
Paired box protein Pax-8 PAX8 Tchem Transcription Factor -2.57435 404.0 460
Retinoblastoma-like protein 2 RBL2 Tbio Non-IDG -2.68094 505.3 303
Cyclin-dependent kinase 2 CDK2 Tchem Kinase -3.40482 2399.0 886