Development Level

Tbio 15 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased erythrocyte cell num... 1 | 39
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
preweaning lethality, complete... 1 | 979

Disease

Cancer 16 | 2,499
psoriasis 15 | 6,694
lung cancer 13 | 4,740
glioblastoma 12 | 5,792
ovarian cancer 11 | 8,520
medulloblastoma, large-cell 10 | 6,241
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
Breast cancer 9 | 3,578
Carcinoma 9 | 11,493
cystic fibrosis 9 | 1,696
malignant mesothelioma 9 | 3,232
osteosarcoma 9 | 7,950
pancreatic cancer 9 | 2,398
lung adenocarcinoma 8 | 2,716
lung carcinoma 8 | 2,843
atypical teratoid / rhabdoid tumor 7 | 5,112
diabetes mellitus 7 | 1,728
ependymoma 7 | 4,679
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
non-small cell lung cancer 7 | 2,890
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
Rheumatoid arthritis 6 | 1,191
adrenocortical carcinoma 6 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
primary pancreatic ductal adenocarcinoma 6 | 1,109
Arthritis 5 | 290
Arthritis, Rheumatoid 5 | 174
Endometriosis 5 | 540
Inflammation 5 | 120
Liver Cirrhosis, Experimental 5 | 769
Mental Depression 5 | 333
acute quadriplegic myopathy 5 | 1,158
chronic rhinosinusitis 5 | 512
dermatomyositis 5 | 966
gastric cancer 5 | 459
group 4 medulloblastoma 5 | 1,855
hepatocellular carcinoma 5 | 547
juvenile dermatomyositis 5 | 1,187
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
Alzheimer's disease 4 | 658
Asthma 4 | 385
Depressive disorder 4 | 409
Heart disease 4 | 306
Hypersensitivity reaction type II disease 4 | 253
Inflammatory bowel disease 4 | 151
Kidney disease 4 | 430
Lung disease 4 | 142
Multiple myeloma 4 | 1,332
Schizophrenia 4 | 1,160
adult high grade glioma 4 | 3,801
group 3 medulloblastoma 4 | 4,104
periodontitis 4 | 293
spina bifida 4 | 1,074
Amyotrophic lateral sclerosis 3 | 451
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Brain Injuries 3 | 65
Breast Neoplasms 3 | 445
Chemical and Drug Induced Liver Injury 3 | 195
Congestive heart failure 3 | 113
Coronary artery disease 3 | 268
Dermatitis 3 | 157
Dermatitis, Allergic Contact 3 | 67
Diabetes Mellitus, Experimental 3 | 108
Glomerulonephritis 3 | 46
Heart failure 3 | 162
Hypersensitivity 3 | 63
Lung Neoplasms 3 | 232
Mammary Neoplasms 3 | 425
Myocardial Ischemia 3 | 169
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Obesity 3 | 678
Pneumonia 3 | 174
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484
non-small cell lung carcinoma 3 | 317
pancreatic carcinoma 3 | 562
posterior fossa group A ependymoma 3 | 468
sarcoidosis 3 | 370
Arthritis, Juvenile 2 | 126
nasopharyngeal carcinoma 2 | 1,058

Tissue

Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Male tissues 20 | 17,142
Skin and soft tissues 20 | 17,230
Liver and Pancreas 19 | 16,750
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Urinary Tract 19 | 16,678
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 13 | 12,091
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145
Nuclear Receptor 1 | 48

WikiPathways Pathway

Hypertrophy Model 20 | 20
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger E-box-binding homeobox 1 ZEB1 Tbio Transcription Factor -2.88752 659.2 460
Growth/differentiation factor 8 MSTN Tbio Non-IDG -3.08307 1338.8 568
Nuclear receptor subfamily 4 group A member 3 NR4A3 Tbio Nuclear Receptor -2.02752 112.7 289
Disintegrin and metalloproteinase domain-containing protein 10 ADAM10 Tchem Enzyme -2.64652 422.4 384
Interferon-related developmental regulator 1 IFRD1 Tbio Non-IDG -1.44715 36.1 100
Ankyrin repeat domain-containing protein 1 ANKRD1 Tbio Non-IDG -1.79794 62.3 159
Cyclic AMP-dependent transcription factor ATF-3 ATF3 Tbio Transcription Factor -2.67021 520.8 401
Protein CYR61 CYR61 Tbio Non-IDG -2.43164 320.5 423
Transcription factor jun-D JUND Tbio Transcription Factor -2.47292 252.6 452
Myogenin MYOG Tbio Transcription Factor -2.97963 827.3 659