Development Level

Tbio 8 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal embryo size 3 | 220
preweaning lethality, complete... 3 | 979
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal head morphology 1 | 10
abnormal placenta size 1 | 20
abnormal startle reflex 1 | 15
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
male infertility 1 | 123
mammalian phenotype 1 | 17
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

lung cancer 11 | 4,740
medulloblastoma, large-cell 11 | 6,241
osteosarcoma 11 | 7,950
glioblastoma 10 | 5,792
malignant mesothelioma 10 | 3,232
Cancer 9 | 2,499
Carcinoma 9 | 11,493
ovarian cancer 9 | 8,520
primitive neuroectodermal tumor 9 | 3,035
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
Liver carcinoma 7 | 240
Breast Neoplasms 6 | 445
Carcinoma, Hepatocellular 6 | 228
Mammary Neoplasms 6 | 425
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Kidney cancer 5 | 2,613
Liver Neoplasms, Experimental 5 | 59
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Adenoid Cystic Carcinoma 4 | 99
Animal Mammary Neoplasms 4 | 136
Carcinoma, Adenoid Cystic 4 | 99
Lung Neoplasms 4 | 232
Mammary Neoplasms, Animal 4 | 136
Mammary Neoplasms, Experimental 4 | 154
Neoplasms, Experimental 4 | 40
Rheumatoid arthritis 4 | 1,191
Salivary Gland Neoplasms 4 | 46
Stomach Neoplasms 4 | 300
Stomach cancer 4 | 30
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
subependymal giant cell astrocytoma 4 | 2,287
Abnormality of metabolism/homeostasis 3 | 134
Adenoma 3 | 167
Colorectal Neoplasms 3 | 243
Endometrial cancer 3 | 311
Endometriosis 3 | 540
Kidney disease 3 | 430
Melanoma 3 | 711
Neoplasm Metastasis 3 | 168
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Bilateral fifth finger clinodactyly 2 | 110
Bladder Neoplasm 2 | 112
Brachydactyly 2 | 156
Chemical and Drug Induced Liver Injury 2 | 195
Colonic Neoplasms 2 | 142
Curvature of little finger 2 | 110
Disease Progression 2 | 136
Esophageal Squamous Cell Carcinoma 2 | 77
Infantile onset 2 | 238
Inflammatory bowel disease 2 | 151
Leukemia 2 | 104
Liver Cirrhosis 2 | 181
Liver disease 2 | 237
Liver neoplasms 2 | 130
Lymphoid leukemia 2 | 160
Neoplasm Invasiveness 2 | 161
Nerve Degeneration 2 | 121
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Somatic mutation 2 | 61
Squamous cell carcinoma 2 | 129
Squamous cell carcinoma of esophagus 2 | 77
Strabismus 2 | 270
Urinary Bladder Neoplasms 2 | 114
Uterine Cervical Neoplasm 2 | 25
Uterine Cervical Neoplasms 2 | 26
Vascular disease 2 | 319
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 7 | 12,091
Transcription Factor 3 | 1,400
Kinase 2 | 634
Enzyme 1 | 4,145

WikiPathways Pathway

H19 action Rb-E2F1 signaling a... 13 | 13
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150
Transcription factor SOX-4 SOX4 Tbio Transcription Factor -2.22104 164.2 211
Cadherin-1 CDH1 Tbio Non-IDG -3.85201 6324.3 1880
Core histone macro-H2A.1 H2AFY Tbio Non-IDG -1.78572 69.6 95
Cysteine and glycine-rich protein 2 CSRP2 Tbio Non-IDG -0.96898 10.3 178
Protein jagged-1 JAG1 Tbio Non-IDG -3.09216 1190.8 473
G1/S-specific cyclin-D1 CCND1 Tchem Non-IDG -3.82232 5737.3 1312
Cyclin-dependent kinase 8 CDK8 Tchem Kinase -2.06508 117.2 342
Cyclin-dependent kinase 4 CDK4 Tclin Kinase -3.24878 1546.3 803
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058