Development Level

Tbio 22 | 11,445
Tchem 9 | 1,598
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal bone structure 3 | 187
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating glucose ... 2 | 126
decreased circulating glycerol... 2 | 16
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
hypoactivity 2 | 132
increased hematocrit 2 | 46
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal locomotor behavior 1 | 24
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
increased cardiac muscle contr... 1 | 8
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
long tibia 1 | 25
male infertility 1 | 123
thrombocytopenia 1 | 56

Disease

Carcinoma 28 | 11,493
osteosarcoma 21 | 7,950
ovarian cancer 19 | 8,520
glioblastoma 18 | 5,792
psoriasis 17 | 6,694
medulloblastoma, large-cell 16 | 6,241
atypical teratoid / rhabdoid tumor 15 | 5,112
Glycogen storage disease 13 | 39
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
subependymal giant cell astrocytoma 11 | 2,287
Autosomal recessive predisposition 10 | 1,442
Kidney cancer 10 | 2,613
invasive ductal carcinoma 10 | 2,951
oligodendroglioma 10 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Breast cancer 9 | 3,578
astrocytic glioma 9 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Cancer 8 | 2,499
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,855
malignant mesothelioma 8 | 3,232
primitive neuroectodermal tumor 8 | 3,035
Astrocytoma, Pilocytic 7 | 3,081
Multiple myeloma 7 | 1,332
Pick disease 7 | 1,894
Waldenstrons macroglobulinemia 7 | 765
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung cancer 7 | 4,740
Alzheimer's disease 6 | 658
Epilepsy 6 | 792
Muscle Weakness 6 | 170
Schizophrenia 6 | 1,160
tuberculosis 6 | 2,010
Hepatomegaly 5 | 285
Hypoglycemia 5 | 152
Myopathy 5 | 185
Rheumatoid arthritis 5 | 1,191
Toxic encephalopathy 5 | 141
astrocytoma 5 | 1,146
lung carcinoma 5 | 2,843
Bipolar Disorder 4 | 666
Hypertension 4 | 396
Muscle hypotonia 4 | 571
Myocardial Ischemia 4 | 169
Ventricular arrhythmia 4 | 27
fibroadenoma 4 | 559
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
pituitary cancer 4 | 1,972
Atopic dermatitis 3 | 952
Cardiomyopathies 3 | 110
Cerebrovascular disease 3 | 238
Creatine phosphokinase serum increased 3 | 110
Dementia 3 | 175
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Elevated creatine kinase 3 | 110
Elevated hepatic transaminases 3 | 81
Emphysema 3 | 12
Heart disease 3 | 306
Hepatic enzyme increased 3 | 81
Hypertriglyceridemia result 3 | 37
Idiopathic scoliosis 3 | 31
Ketonemia 3 | 11
Ketosis 3 | 11
Liver Dysfunction 3 | 99
Liver enzymes abnormal 3 | 81
Liver function test increased 3 | 81
Liver function tests abnormal finding 3 | 81
Long QT syndrome 1 3 | 20
Low intelligence 3 | 645
Malignant hyperthermia 3 | 26
Mental deficiency 3 | 645
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Osteoarthritis 3 | 184
Otitis externa 3 | 10
Pathological accumulation of air in tissues 3 | 10
Pertussis 3 | 20
Poor school performance 3 | 645
Seizures 3 | 596
Skeletal muscle atrophy 3 | 139
Sporotrichosis 3 | 10
Subclinical abnormal liver function tests 3 | 81
Tetanus 3 | 68
Transaminases increased 3 | 81
hereditary spastic paraplegia 3 | 318
interstitial cystitis 3 | 2,312
muscle degeneration 3 | 139
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Cardiovascular System 35 | 15,192
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Respiratory system 35 | 16,393

Target Family

Enzyme 26 | 4,145
Kinase 6 | 634
Non-IDG 4 | 12,091

WikiPathways Pathway

Glycogen Metabolism 36 | 36
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform PPP2R5D Tbio Enzyme -0.70843 3.59 261
Phosphorylase b kinase regulatory subunit alpha, liver isoform PHKA2 Tbio Kinase -2.21111 153.2 59
Glycogen phosphorylase, brain form PYGB Tbio Enzyme -1.98823 97.5 415
Glycogen phosphorylase, muscle form PYGM Tchem Enzyme -2.24324 158.2 208
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform PHKA1 Tbio Kinase -1.17814 14.3 71
Calmodulin-2 CALM3 Tclin Non-IDG -3.59834 5859.5 0
Calmodulin-3 CALM3 Tclin Non-IDG -3.59140 5859.5 0
Phosphorylase b kinase regulatory subunit beta PHKB Tbio Enzyme -1.13261 11.6 113
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform PHKG1 Tchem Kinase -0.95927 8.64 252
Phosphoglucomutase-1 PGM1 Tbio Enzyme -2.68870 491.5 141