Development Level

Tbio 17 | 10,625
Tchem 3 | 1,890
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
decreased lean body mass 2 | 195
embryonic lethality prior to o... 2 | 148
abnormal QRS complex 1 | 25
abnormal embryo size 1 | 112
abnormal lens morphology 1 | 73
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating lactate ... 1 | 1
decreased eosinophil cell numb... 1 | 41
decreased total body fat amoun... 1 | 186
enlarged lymph nodes 1 | 27
hydrometra 1 | 13
increased B cell number 1 | 23
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased mature B cell number 1 | 12
increased mean platelet volume 1 | 19
increased prepulse inhibition 1 | 21
increased red blood cell distr... 1 | 21
thrombocytosis 1 | 23

Disease

ovarian cancer 12 | 8,484
osteosarcoma 10 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
lung cancer 7 | 4,466
medulloblastoma, large-cell 7 | 6,234
psoriasis 6 | 6,685
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
Duchenne muscular dystrophy 4 | 602
Multiple myeloma 4 | 1,327
atypical teratoid / rhabdoid tumor 4 | 4,369
glioblastoma 4 | 5,572
invasive ductal carcinoma 4 | 2,950
non-small cell lung cancer 4 | 2,798
Rheumatoid Arthritis 3 | 1,160
Sengers syndrome 3 | 17
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 918
adult high grade glioma 3 | 2,148
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
oligodendroglioma 3 | 2,849
pilocytic astrocytoma 3 | 3,086
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 2,087
Breast cancer 2 | 3,094
Cataract 2 | 104
Chondrodysplasia punctata 2 | 41
Intellectual disability 2 | 573
Lipodystrophy 2 | 32
Liver disease 2 | 219
Myocardial Ischemia 2 | 169
Rhizomelic chondrodysplasia punctata 2 | 11
Toxic encephalopathy 2 | 131
acute quadriplegic myopathy 2 | 1,157
breast carcinoma 2 | 1,614
dermatomyositis 2 | 933
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 2,514
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 2,254
interstitial cystitis 2 | 2,299
juvenile dermatomyositis 2 | 1,189
limb girdle muscular dystrophy 2B 2 | 74
lung adenocarcinoma 2 | 2,713
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
nephrosclerosis 2 | 329
non primary Sjogren syndrome sicca 2 | 840
pediatric high grade glioma 2 | 2,712
primitive neuroectodermal tumor 2 | 3,031
sonic hedgehog group medulloblastoma 2 | 1,482
tuberculosis and treatment for 6 months 2 | 686
Acquired immunodeficiency syndrome 1 | 164
Adrenoleukodystrophy 1 | 31
Alzheimer's disease 1 | 644
Amyotrophic Lateral Sclerosis 1 | 431
Arthritis 1 | 248
Atherosclerosis 1 | 275
Atopic dermatitis 1 | 944
Barth syndrome 1 | 23
Blepharophimosis 1 | 17
Cancer 1 | 2,346
Cerebrovascular disease 1 | 231
Chronic Lymphocytic Leukemia 1 | 242
Chronic obstructive pulmonary disease 1 | 146
Colorectal Neoplasms 1 | 217
Coronary artery disease 1 | 240
Dentin caries 1 | 4
Endometriosis 1 | 535
Eye disease 1 | 55
Fatty liver disease 1 | 84
Fungal meningitis 1 | 7
Gaucher disease type 1 1 | 171
IGA Glomerulonephritis 1 | 454
Infantile refsum disease 1 | 19
Leigh disease 1 | 81
Lipid metabolism disorder 1 | 102
Muscular dystrophy 1 | 48
Myoglobinuria 1 | 11
Narcolepsy 1 | 58
Osteomyelitis 1 | 20
Refsum disease 1 | 21
Reperfusion Injury 1 | 84
Spastic quadriplegia 1 | 7
Zellweger Syndrome 1 | 38
aldosterone-producing adenoma 1 | 664
atypical teratoid/rhabdoid tumor 1 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
colon cancer 1 | 1,475
cystic fibrosis 1 | 1,665
fibroadenoma 1 | 557
glioblastoma multiforme 1 | 347
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
hereditary spastic paraplegia 1 | 313
inflammatory breast cancer 1 | 404
pituitary cancer 1 | 1,972
tuberculosis 1 | 1,557
tuberculosis and treatment for 3 months 1 | 327
type II diabetes mellitus and post-ischemic heart failure 1 | 89

Tissue

Blood and immune system 21 | 17,995
Digestive Tract 21 | 18,473
Endocrine System 21 | 18,512
Female tissues 21 | 18,647
Liver and Pancreas 21 | 18,136
Nervous System 21 | 18,561
Skin and soft tissues 21 | 18,115
Urinary Tract 21 | 18,444
Cardiovascular System 20 | 17,958
Male tissues 20 | 17,969
Respiratory system 20 | 17,484

Target Family

Enzyme 17 | 4,146
Kinase 4 | 634

WikiPathways Pathway

Glycerophospholipid Biosynthet... 21 | 21
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial PGS1 Tdark Enzyme -0.35218 2.20 100
Phosphatidylserine synthase 1 PTDSS1 Tbio Enzyme -1.84361 76.0 90
Choline/ethanolaminephosphotransferase 1 CEPT1 Tbio Enzyme -1.62619 45.7 75
Phospholipase A2, membrane associated PLA2G2A Tchem Enzyme -2.81886 723.7 112
Cardiolipin synthase (CMP-forming) CRLS1 Tbio Enzyme -0.79126 6.24 93
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha PIP5K1A Tbio Kinase -0.71127 4.98 106
2-acylglycerol O-acyltransferase 3 MOGAT3 Tbio Enzyme -1.00860 10.7 59
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 PTPMT1 Tchem Enzyme -1.33820 22.8 98
Cholinephosphotransferase 1 CHPT1 Tbio Enzyme -1.41901 23.5 74
Phosphatidylinositol 4-kinase type 2-alpha PI4K2A Tbio Kinase -2.82149 688.5 127