Development Level

Tbio 17 | 11,651
Tdark 3 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

cataract 1 | 92
decreased grip strength 1 | 116

Disease

Carcinoma 13 | 11,493
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
glioblastoma 10 | 5,792
lung cancer 10 | 4,740
ovarian cancer 10 | 8,520
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
medulloblastoma, large-cell 8 | 6,241
Astrocytoma, Pilocytic 7 | 3,081
interstitial cystitis 7 | 2,312
malignant mesothelioma 7 | 3,232
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 5 | 2,951
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
cystic fibrosis 4 | 1,696
gastric carcinoma 4 | 807
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
non primary Sjogren syndrome sicca 4 | 891
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
Cancer 3 | 2,499
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
lung carcinoma 3 | 2,843
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Bipolar Disorder 2 | 666
Hemolytic-Uremic Syndrome 2 | 30
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
Nonorganic psychosis 2 | 84
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
Psychotic Disorders 2 | 151
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Waldenstrons macroglobulinemia 2 | 765
astrocytic glioma 2 | 2,597
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung carcinoma 2 | 317
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Alcoholic Intoxication 1 | 34
Alcoholic Intoxication, Chronic 1 | 289
Amyotrophic lateral sclerosis 1 | 451
Cardiovascular system disease 1 | 246
Coronary artery disease 1 | 268
Crohn Disease 1 | 45
Dermatitis, Allergic Contact 1 | 67
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Diarrhea 1 | 253
Disease of mental health 1 | 36
Disease of metabolism 1 | 18
Glomerulonephritis, IGA 1 | 34
IGA Glomerulonephritis 1 | 50
Influenza 1 | 142
Kidney disease 1 | 430
Lipid metabolism disorder 1 | 114
Liver Cirrhosis, Experimental 1 | 769
Liver disease 1 | 237
Liver diseases 1 | 87
Lymphoid leukemia 1 | 160
Melanoma 1 | 711
Mood Disorders 1 | 184
Pancreatic Neoplasm 1 | 85
Pancreatic Neoplasms 1 | 85
Type 2 diabetes mellitus 1 | 272
Vascular disease 1 | 319
acute myeloid leukemia 1 | 783
aldosterone-producing adenoma 1 | 665
atypical teratoid/rhabdoid tumor 1 | 357
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
facioscapulohumeral dystrophy 1 | 288
fibroadenoma 1 | 559
medulloblastoma 1 | 720
pancreatic carcinoma 1 | 562
sonic hedgehog group medulloblastoma 1 | 467
urothelial carcinoma 1 | 318

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Blood and immune system 20 | 16,909
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678
Cardiovascular System 19 | 15,192
Respiratory system 19 | 16,393

Target Family

Enzyme 21 | 4,145
Non-IDG 1 | 12,091

WikiPathways Pathway

Globo Sphingolipid Metabolism 22 | 22
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

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