Development Level

Tbio 14 | 10,625
Tchem 4 | 1,890
Tdark 4 | 7,003

IMPC Term

preweaning lethality, incomple... 1 | 260

Disease

atypical teratoid / rhabdoid tumor 10 | 4,369
lung cancer 10 | 4,473
ovarian cancer 10 | 8,492
glioblastoma 9 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
lung adenocarcinoma 9 | 2,714
osteosarcoma 9 | 7,933
psoriasis 9 | 6,685
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
medulloblastoma, large-cell 8 | 6,234
interstitial cystitis 7 | 2,299
malignant mesothelioma 7 | 3,163
pilocytic astrocytoma 7 | 3,086
Breast cancer 6 | 3,099
group 4 medulloblastoma 6 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
posterior fossa group A ependymoma 6 | 1,511
ependymoma 5 | 2,514
invasive ductal carcinoma 5 | 2,950
oligodendroglioma 5 | 2,849
pediatric high grade glioma 5 | 2,712
adult high grade glioma 4 | 2,148
cystic fibrosis 4 | 1,670
gastric carcinoma 4 | 832
non-small cell lung cancer 4 | 2,798
pancreatic cancer 4 | 2,300
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,031
spina bifida 4 | 1,064
active Crohn's disease 3 | 918
adrenocortical carcinoma 3 | 1,427
astrocytoma 3 | 1,493
colon cancer 3 | 1,475
lung carcinoma 3 | 2,844
medulloblastoma 3 | 1,524
non primary Sjogren syndrome sicca 3 | 840
non-small cell lung carcinoma 3 | 413
primary pancreatic ductal adenocarcinoma 3 | 1,271
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 2,087
Blood group p phenotype (finding) 2 | 2
Cancer 2 | 2,346
Multiple myeloma 2 | 1,328
Pick disease 2 | 1,893
Prostatic Neoplasms 2 | 471
Rheumatoid Arthritis 2 | 1,171
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 477
astrocytic glioma 2 | 2,241
cutaneous lupus erythematosus 2 | 1,056
diabetes mellitus 2 | 1,663
ductal carcinoma in situ 2 | 1,745
hemolytic-uremic syndrome 2 | 28
nasopharyngeal carcinoma 2 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
primary Sjogren syndrome 2 | 789
Alzheimer's disease 1 | 644
Amyotrophic Lateral Sclerosis 1 | 432
Bipolar Disorder 1 | 266
Burkitt Lymphoma 1 | 19
Carcinoma 1 | 2,147
Cardiovascular system disease 1 | 194
Common variable immunodeficiency 1 | 98
Coronary artery disease 1 | 240
Crohn Disease 1 | 97
Dermatitis, Allergic Contact 1 | 66
Diabetes Mellitus, Non-Insulin-Dependent 1 | 161
Disease of mental health 1 | 22
Disease of metabolism 1 | 15
Down syndrome 1 | 548
Drug-Induced Liver Injury 1 | 118
Epithelial ovarian cancer 1 | 19
IGA Glomerulonephritis 1 | 454
Influenza 1 | 142
Intraocular pressure disorder 1 | 8
Lipid metabolism disorder 1 | 102
Liver disease 1 | 219
Liver diseases 1 | 66
Malaria 1 | 140
Malignant neoplasm of esophagus 1 | 18
Mastitis 1 | 48
Metabolic syndrome X 1 | 155
Muscle Weakness 1 | 92
Pancreatic Neoplasm 1 | 79
Sclerosing cholangitis 1 | 17
Type 2 diabetes mellitus 1 | 192
Venous Thromboembolism 1 | 34
acute myeloid leukemia 1 | 785
aldosterone-producing adenoma 1 | 664
atypical teratoid/rhabdoid tumor 1 | 1,095
breast carcinoma 1 | 1,614
chronic rhinosinusitis 1 | 512
facioscapulohumeral dystrophy 1 | 286
fibroadenoma 1 | 557
glioblastoma multiforme 1 | 347
pancreatic carcinoma 1 | 567
sonic hedgehog group medulloblastoma 1 | 1,482
tuberculosis 1 | 1,563
tuberculosis and treatment for 6 months 1 | 686
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 22 | 17,995
Cardiovascular System 22 | 17,958
Digestive Tract 22 | 18,473
Female tissues 22 | 18,647
Endocrine System 21 | 18,512
Liver and Pancreas 21 | 18,136
Male tissues 21 | 17,969
Nervous System 21 | 18,561
Respiratory system 21 | 17,484
Skin and soft tissues 21 | 18,115
Urinary Tract 21 | 18,444

Target Family

Enzyme 21 | 4,146
Non-IDG 1 | 11,969

WikiPathways Pathway

Globo Sphingolipid Metabolism 22 | 22
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

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