Development Level

Tbio 26 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
preweaning lethality, complete... 3 | 979
decreased vertical activity 2 | 208
increased bone mineral density 2 | 72
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal rib morphology 1 | 10
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cataract 1 | 92
decreased circulating total pr... 1 | 49
decreased leukocyte cell numbe... 1 | 73
decreased total retina thickne... 1 | 17
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
increased bone mineral content 1 | 108
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
vertebral fusion 1 | 23

Disease

ovarian cancer 24 | 8,520
Carcinoma 21 | 11,493
lung cancer 21 | 4,740
medulloblastoma, large-cell 21 | 6,241
Breast cancer 17 | 3,578
glioblastoma 17 | 5,792
group 3 medulloblastoma 17 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
osteosarcoma 16 | 7,950
ependymoma 14 | 4,679
non-small cell lung cancer 14 | 2,890
psoriasis 14 | 6,694
adrenocortical carcinoma 13 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
malignant mesothelioma 13 | 3,232
primitive neuroectodermal tumor 13 | 3,035
Astrocytoma, Pilocytic 12 | 3,081
Cancer 12 | 2,499
adult high grade glioma 12 | 3,801
atypical teratoid / rhabdoid tumor 12 | 5,112
nasopharyngeal carcinoma 10 | 1,058
pancreatic cancer 10 | 2,398
invasive ductal carcinoma 9 | 2,951
Endometriosis 8 | 540
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
lung adenocarcinoma 8 | 2,716
oligodendroglioma 8 | 2,850
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pituitary cancer 7 | 1,972
ulcerative colitis 7 | 1,819
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
Multiple myeloma 6 | 1,332
astrocytic glioma 6 | 2,597
lung carcinoma 6 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary Sjogren syndrome 6 | 735
subependymal giant cell astrocytoma 6 | 2,287
Alzheimer's disease 5 | 658
Neoplasm Metastasis 5 | 168
Prostatic Neoplasms 5 | 495
Adenocarcinoma 4 | 122
Adenocarcinoma of lung 4 | 142
Adenoma 4 | 167
Anemia 4 | 365
Carcinoma, Hepatocellular 4 | 228
Chronic Lymphocytic Leukemia 4 | 262
Cognitive delay 4 | 608
Colonic Neoplasms 4 | 142
Disease Progression 4 | 136
Familial adenomatous polyposis 4 | 32
Global developmental delay 4 | 608
Immune system cancer 4 | 140
Kidney cancer 4 | 2,613
Liver Cirrhosis, Experimental 4 | 769
Liver carcinoma 4 | 240
Lung Neoplasms 4 | 232
Lymphoid leukemia 4 | 160
Mental and motor retardation 4 | 608
Pancreatic Neoplasms 4 | 85
Short stature 4 | 531
Skin cancer 4 | 469
Stomach Neoplasms 4 | 300
acute quadriplegic myopathy 4 | 1,158
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
medulloblastoma 4 | 720
tuberculosis 4 | 2,010
Bladder Neoplasm 3 | 112
Colorectal Neoplasms 3 | 243
Disease Models, Animal 3 | 155
Esophageal carcinoma 3 | 16
Leukopenia 3 | 72
Liver neoplasms 3 | 130
Lung disease 3 | 142
Melanoma 3 | 711
Mesothelioma, Malignant 3 | 105
Micromelia 3 | 58
Osteoarthritis 3 | 184
Pancreatic Neoplasm 3 | 85
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
Squamous cell carcinoma 3 | 129
Thrombocytopenia 3 | 197
Urinary Bladder Neoplasms 3 | 114
Urinary bladder cancer 3 | 36
Uterine Cervical Neoplasm 3 | 25
Uterine Cervical Neoplasms 3 | 26
Vascular disease 3 | 319
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
hepatocellular carcinoma 3 | 547
juvenile dermatomyositis 3 | 1,187
pediatric high grade glioma 3 | 1,064

Tissue

Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Respiratory system 30 | 16,393

Target Family

Non-IDG 26 | 12,091
Enzyme 2 | 4,145
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Kinase 1 | 634

WikiPathways Pathway

Gastric Cancer Network 2 33 | 33
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SNRPN upstream reading frame protein SNURF Tbio Non-IDG -1.05125 8.44 12
Chromosome transmission fidelity protein 8 homolog CHTF8 Tbio Non-IDG 0.00000 10
Chromosome transmission fidelity protein 8 homolog isoform 2 CHTF8 Tdark Non-IDG 0.00000 10
Protein ELYS AHCTF1 Tbio Non-IDG -1.39546 23.9 74
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.88264 723.0 847
Replication factor C subunit 3 RFC3 Tbio Non-IDG -1.30866 19.7 176
Placenta-specific gene 8 protein PLAC8 Tbio Non-IDG -1.79564 62.5 24
Ubiquitin-conjugating enzyme E2 C UBE2C Tbio Non-IDG -1.93680 92.1 352
Collagen alpha-3(IX) chain COL9A3 Tbio Non-IDG -1.35534 21.6 115
E3 ubiquitin-protein ligase RNF144B RNF144B Tbio Enzyme -1.43635 26.6 245