Development Level

Tbio 30 | 11,651
Tdark 22 | 6,593
Tchem 20 | 1,388
Tclin 20 | 612

Collection

RFA-RM-18-021 15 | 328
GPCR: IDG Consortium (Targets) 14 | 126
GPCR: IDG Consortium (Complete... 6 | 25

IMPC Phenotype

decreased bone mineral content 4 | 151
decreased vertical activity 4 | 208
decreased bone mineral density 3 | 126
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
absent startle reflex 2 | 24
decreased heart weight 2 | 27
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
enlarged heart 2 | 210
hyperactivity 2 | 148
increased circulating creatini... 2 | 38
increased circulating sodium l... 2 | 71
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal tail length 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
mammalian phenotype 1 | 17
thrombocytopenia 1 | 56

Disease

Carcinoma 75 | 11,493
psoriasis 30 | 6,694
osteosarcoma 29 | 7,950
glioblastoma 26 | 5,792
medulloblastoma, large-cell 26 | 6,241
atypical teratoid / rhabdoid tumor 25 | 5,112
ovarian cancer 23 | 8,520
ependymoma 19 | 4,679
invasive ductal carcinoma 19 | 2,951
lung cancer 19 | 4,740
Astrocytoma, Pilocytic 18 | 3,081
interstitial cystitis 18 | 2,312
Cancer 17 | 2,499
Schizophrenia 17 | 1,160
adult high grade glioma 17 | 3,801
Breast cancer 16 | 3,578
Kidney cancer 16 | 2,613
lung adenocarcinoma 16 | 2,716
group 3 medulloblastoma 14 | 4,104
lung carcinoma 14 | 2,843
oligodendroglioma 13 | 2,850
Asthma 12 | 385
astrocytic glioma 12 | 2,597
malignant mesothelioma 12 | 3,232
non-small cell lung cancer 12 | 2,890
ulcerative colitis 12 | 1,819
Bipolar Disorder 11 | 666
Depressive disorder 11 | 409
Epilepsy 11 | 792
cutaneous lupus erythematosus 11 | 1,057
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pituitary cancer 11 | 1,972
diabetes mellitus 10 | 1,728
tuberculosis 10 | 2,010
Alcoholic Intoxication, Chronic 9 | 289
Mental Depression 9 | 333
Mood Disorders 9 | 184
Multiple Sclerosis 9 | 540
Parkinson's disease 9 | 392
ductal carcinoma in situ 9 | 1,745
subependymal giant cell astrocytoma 9 | 2,287
Allergic rhinitis 8 | 95
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
medulloblastoma 8 | 720
Alcohol dependence 7 | 107
Attention deficit hyperactivity disorder 7 | 278
Autistic Disorder 7 | 364
Autosomal recessive predisposition 7 | 1,442
Endometriosis 7 | 540
Major Depressive Disorder 7 | 301
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pancreatic cancer 7 | 2,398
primary Sjogren syndrome 7 | 735
Common cold 6 | 69
Melanoma 6 | 711
Migraine 6 | 83
Nasal congestion 6 | 23
Nasal discharge 6 | 25
Obesity 6 | 678
Pain 6 | 103
Pick disease 6 | 1,894
Rheumatoid arthritis 6 | 1,191
Seizures 6 | 596
Skin cancer 6 | 469
Unipolar Depression 6 | 250
adrenocortical carcinoma 6 | 1,428
primitive neuroectodermal tumor 6 | 3,035
Alzheimer's disease 5 | 658
Attention Deficit Disorder with Hyperactivity 5 | 21
Bronchitis 5 | 43
Influenza-like symptoms 5 | 16
Liver Cirrhosis, Experimental 5 | 769
Liver cancer 5 | 604
Pulmonary emphysema 5 | 48
Sinus headache 5 | 16
Substance abuse 5 | 59
Vascular disease 5 | 319
cystic fibrosis 5 | 1,696
mucosa-associated lymphoid tissue lymphoma 5 | 484
primary pancreatic ductal adenocarcinoma 5 | 1,109
Amphetamine-Related Disorders 4 | 74
Anxiety Disorders 4 | 38
Cocaine-Related Disorders 4 | 92
Dementia 4 | 175
Endometrial cancer 4 | 311
Hyperalgesia 4 | 83
Hypertension 4 | 396
Hypertensive disorder 4 | 57
Immune system cancer 4 | 140
Liver Cirrhosis 4 | 181
Open-angle glaucoma 4 | 27
Pain agnosia 4 | 104
Panic disorder 4 | 61
Status Epilepticus 4 | 98
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
non-small cell lung carcinoma 4 | 317
obsessive-compulsive disorder 4 | 61
pediatric high grade glioma 4 | 1,064

Tissue

Endocrine System 83 | 18,159
Nervous System 69 | 16,725
Digestive Tract 67 | 17,369
Female tissues 66 | 17,400
Blood and immune system 65 | 16,909
Male tissues 64 | 17,142
Skin and soft tissues 64 | 17,230
Liver and Pancreas 61 | 16,750
Urinary Tract 61 | 16,678
Respiratory system 57 | 16,393
Cardiovascular System 54 | 15,192

Target Family

GPCR 71 | 408
oGPCR 20 | 421
Enzyme 1 | 4,145

WikiPathways Pathway

GPCRs, Other 92 | 92
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G-protein coupled receptor 176 GPR176 Tbio GPCR -2.38327 235.4 133
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase ALG6 Tbio Enzyme -1.41256 26.8 76
Gonadotropin-releasing hormone receptor GNRHR Tclin GPCR -2.63054 444.8 313
Adenosine receptor A3 ADORA3 Tchem GPCR -2.39734 255.0 54
Neurotensin receptor type 1 NTSR1 Tchem GPCR -2.94526 841.8 215
Relaxin receptor 1 RXFP1 Tbio GPCR -2.21377 176.7 266
Leucine-rich repeat-containing G-protein coupled receptor 6 LGR6 Tbio GPCR -1.41906 26.5 156
G-protein coupled receptor 55 GPR55 Tchem GPCR -2.15109 160.6 121
Endothelin-1 receptor EDNRA Tclin GPCR -2.86513 644.6 259
Olfactory receptor 2A5 OR2A5 Tdark oGPCR 0.60 0.17 65