Development Level

Tbio 9 | 11,445
Tclin 8 | 613
Tchem 6 | 1,598

Collection

GPCR: IDG Consortium (Targets) 3 | 126
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal sleep behavior 1 | 70
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
enlarged heart 1 | 210
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytopenia 1 | 56

Disease

Carcinoma 22 | 11,493
glioblastoma 10 | 5,792
psoriasis 10 | 6,694
ependymoma 9 | 4,679
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
Kidney cancer 7 | 2,613
adult high grade glioma 7 | 3,801
lung adenocarcinoma 7 | 2,716
lung cancer 7 | 4,740
lung carcinoma 7 | 2,843
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
non-small cell lung cancer 6 | 2,890
osteosarcoma 6 | 7,950
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
Astrocytoma, Pilocytic 4 | 3,081
Obesity 4 | 678
diabetes mellitus 4 | 1,728
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Depressive disorder 3 | 409
Hypertension 3 | 396
Lung diseases 3 | 50
Mental Depression 3 | 333
Osteoporosis 3 | 363
Postmenopausal osteoporosis 3 | 19
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
non-small cell lung carcinoma 3 | 317
pituitary cancer 3 | 1,972
post-traumatic stress disorder 3 | 40
Anhedonia 2 | 27
Anorexia 2 | 43
Anxiety Disorders 2 | 38
Autosomal recessive predisposition 2 | 1,442
Cocaine-Related Disorders 2 | 92
Dermatophytosis 2 | 11
Gastric ulcer 2 | 33
Glucocorticoid Induced Osteoporosis 2 | 4
Holoprosencephaly 3 2 | 7
Hypercalcemia 2 | 59
Hyperglycemia 2 | 137
Hypertensive disease 2 | 292
Hypoglycemia 2 | 152
Hypogonadal Osteoporosis in Males 2 | 4
Immune system cancer 2 | 140
Irritable bowel syndrome 2 | 60
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Lymphoid leukemia 2 | 160
Melanoma 2 | 711
Mood Disorders 2 | 184
Panic disorder 2 | 61
Short stature 2 | 531
Type 2 Diabetes Mellitus Treatment Adjunct 2 | 7
Type 2 diabetes mellitus 2 | 272
adrenocortical adenoma 2 | 131
chronic kidney disease 2 | 90
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
pediatric high grade glioma 2 | 1,064
Acquired cubitus valgus 1 | 18
Argentine hemorrhagic fever 1 | 10
Depressive Disorder, Major 1 | 19
Hyperphosphaturia 1 | 21
Invasive aspergillosis 1 | 6
Isolated somatotropin deficiency 1 | 30
Lethal skeletal dysplasia 1 | 6
Maffucci syndrome 1 | 6
Mesomelia 1 | 8
Metaphyseal irregularity 1 | 23
Narrow pelvis 1 | 6
Osteosclerosis 1 | 31
Pituitary dwarfism 1 | 6
Pituitary hypoplasia 1 | 23
Rosacea 1 | 25
Sacral agenesis 1 | 3
Septooptic dysplasia 1 | 19
Shigellosis 1 | 21
Short tubular bones 1 | 22
Sialuria 1 | 9
Splayed metaphyses 1 | 19
Urine phosphorous concentration above normal 1 | 21
Vertebrobasilar insufficiency 1 | 9

Tissue

Endocrine System 23 | 18,159
Urinary Tract 23 | 16,678
Digestive Tract 22 | 17,369
Liver and Pancreas 22 | 16,750
Skin and soft tissues 22 | 17,230
Female tissues 21 | 17,400
Nervous System 21 | 16,725
Cardiovascular System 20 | 15,192
Male tissues 20 | 17,142
Respiratory system 20 | 16,393
Blood and immune system 19 | 16,909

Target Family

GPCR 23 | 408

WikiPathways Pathway

GPCRs, Class B Secretin-like 23 | 23
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G protein-coupled receptor E2 ADGRE2 Tbio GPCR -1.67862 48.2 312
Adhesion G protein-coupled receptor L4 ADGRL4 Tbio GPCR -2.27628 174.3 140
Adhesion G protein-coupled receptor L1 ADGRL1 Tbio GPCR -1.81420 60.5 108
Adhesion G-protein coupled receptor G2 ADGRG2 Tbio GPCR -1.34620 24.4 71
Adhesion G protein-coupled receptor E1 ADGRE1 Tbio GPCR -1.33987 18.7 430
Secretin receptor SCTR Tclin GPCR -1.58176 34.8 193
Glucagon-like peptide 1 receptor GLP1R Tclin GPCR -2.92059 820.5 306
Growth hormone-releasing hormone receptor GHRHR Tclin GPCR -2.10486 138.0 205
Adhesion G protein-coupled receptor L3 ADGRL3 Tbio GPCR -2.72560 511.0 123
Glucagon-like peptide 2 receptor GLP2R Tclin GPCR -1.45855 24.5 221