Development Level

Tclin 20 | 613
Tbio 8 | 11,445
Tchem 1 | 1,598

Collection

Ion Channel: IDG Consortium (T... 3 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

abnormal cecum morphology 1 | 7
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
absent pinna reflex 1 | 23
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
increased circulating free fat... 1 | 20
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Carcinoma 27 | 11,493
Epilepsy 21 | 792
medulloblastoma, large-cell 20 | 6,241
atypical teratoid / rhabdoid tumor 19 | 5,112
glioblastoma 19 | 5,792
ependymoma 17 | 4,679
Anxiety 16 | 136
General anesthesia 16 | 53
Insomnia 16 | 20
Tonic-clonic epilepsy 16 | 47
adult high grade glioma 16 | 3,801
Kidney cancer 15 | 2,613
oligodendroglioma 15 | 2,850
Autistic Disorder 14 | 364
group 3 medulloblastoma 14 | 4,104
primitive neuroectodermal tumor 14 | 3,035
Alcoholic Intoxication, Chronic 13 | 289
Astrocytoma, Pilocytic 13 | 3,081
Schizophrenia 13 | 1,160
Sedation as Adjunct to Anesthesia 13 | 15
psoriasis 12 | 6,694
astrocytic glioma 11 | 2,597
ovarian cancer 11 | 8,520
subependymal giant cell astrocytoma 11 | 2,287
Pick disease 9 | 1,894
Status Epilepticus 9 | 98
Alcohol dependence 8 | 107
Alcohol withdrawal delirium 8 | 11
Alcohol withdrawal syndrome 8 | 20
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Induce Anterograde Amnesia 8 | 9
Local anesthesia 8 | 40
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Spasticity 8 | 26
Tetanus 8 | 68
osteosarcoma 8 | 7,950
Anxiety associated with Menopause 7 | 7
Bipolar Disorder 7 | 666
Conscious sedation 7 | 10
Feeling agitated 7 | 7
Generalized anxiety disorder 7 | 29
Irritable bowel syndrome 7 | 60
Mixed anxiety and depressive disorder 7 | 12
Panic disorder 7 | 61
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic Ulcer 7 | 27
Pre-Op Apprehension 7 | 10
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
lung carcinoma 7 | 2,843
Alcoholism 6 | 45
Breast cancer 6 | 3,578
Initial insomnia 6 | 8
Pain with Tension and Anxiety 6 | 6
pituitary cancer 6 | 1,972
Disorders of initiating and maintaining sleep 5 | 8
Epilepsy characterized by intractable complex partial seizures 5 | 28
Mood Disorders 5 | 184
Seizures 5 | 596
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Absence Epilepsy 4 | 22
Absence seizure 4 | 12
Atonic seizure 4 | 4
Cerebral Ischemia 4 | 37
Cocaine-Related Disorders 4 | 92
Cognitive delay 4 | 608
Depressive disorder 4 | 409
Epileptic drop attack 4 | 11
Global developmental delay 4 | 608
Hypotonic seizures 4 | 11
Intellectual disability 4 | 1,016
Lennox-Gastaut syndrome 4 | 34
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
Myoclonic seizure 4 | 4
Schizoaffective Disorder 4 | 55
Seizure disorder 4 | 4
Simple partial seizure 4 | 26
Tetanus Adjunct Treatment 4 | 8
interstitial cystitis 4 | 2,312
Autism spectrum disorder 3 | 101
Bipolar disorder in remission 3 | 19
Dysuria 3 | 26
Electroencephalogram abnormal 3 | 101
Localization-related epilepsy 3 | 13
Rheumatoid arthritis 3 | 1,191
Tonic-clonic seizure 3 | 11
Tremor 3 | 113
Urinary Tract Irritation 3 | 24
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398

Tissue

Nervous System 29 | 16,725
Endocrine System 28 | 18,159
Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Female tissues 25 | 17,400
Male tissues 25 | 17,142
Skin and soft tissues 25 | 17,230
Urinary Tract 23 | 16,678
Liver and Pancreas 20 | 16,750
Cardiovascular System 19 | 15,192
Respiratory system 19 | 16,393

Target Family

Ion Channel 16 | 344
Non-IDG 6 | 12,091
Transporter 3 | 473
Enzyme 2 | 4,145
GPCR 2 | 408

WikiPathways Pathway

GABA receptor Signaling 29 | 29
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 Tclin Ion Channel -0.98683 8.48 87
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.13205 136.0 202
4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 Tbio Enzyme -1.43954 27.0 162
Gamma-aminobutyric acid receptor subunit theta GABRQ Tclin Ion Channel -0.83091 6.58 66
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.28622 17.7 291
Gamma-aminobutyric acid type B receptor subunit 2 GABBR2 Tclin GPCR -1.97367 92.4 395
Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1 Tclin Ion Channel -1.79984 58.4 301
Sodium- and chloride-dependent GABA transporter 3 SLC6A11 Tbio Transporter -2.26927 175.1 75
Gamma-aminobutyric acid receptor subunit alpha-5 GABRA5 Tclin Ion Channel -1.57578 34.2 189
4-aminobutyrate aminotransferase, mitochondrial ABAT Tclin Enzyme -2.02391 104.3 204