Development Level

Tbio 19 | 11,445
Tchem 11 | 1,598
Tclin 7 | 613

IMPC Phenotype

decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal skin condition 1 | 6
abnormal testis morphology 1 | 43
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased thermal nociceptive ... 1 | 2
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged uterus 1 | 11
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 25 | 11,493
Cancer 24 | 2,499
ovarian cancer 20 | 8,520
diabetes mellitus 18 | 1,728
psoriasis 18 | 6,694
tuberculosis 17 | 2,010
Arthritis 16 | 290
glioblastoma 16 | 5,792
lung cancer 16 | 4,740
Asthma 15 | 385
lung carcinoma 15 | 2,843
malignant mesothelioma 14 | 3,232
Schizophrenia 13 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
medulloblastoma, large-cell 13 | 6,241
osteosarcoma 13 | 7,950
Hypersensitivity reaction type II disease 12 | 253
Kidney disease 12 | 430
Multiple Sclerosis 12 | 540
ulcerative colitis 12 | 1,819
Astrocytoma, Pilocytic 11 | 3,081
Liver Cirrhosis, Experimental 11 | 769
adult high grade glioma 11 | 3,801
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Hypertension 10 | 396
Inflammatory bowel disease 10 | 151
Influenza 10 | 142
Lung disease 10 | 142
Heart disease 9 | 306
Liver disease 9 | 237
Pneumonia 9 | 174
cutaneous lupus erythematosus 9 | 1,057
cystic fibrosis 9 | 1,696
ependymoma 9 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
subependymal giant cell astrocytoma 9 | 2,287
Atherosclerosis 8 | 291
Brain Ischemia 8 | 110
Cerebrovascular disease 8 | 238
Hypertensive disease 8 | 292
Malaria 8 | 160
Obesity 8 | 678
Reperfusion Injury 8 | 86
juvenile dermatomyositis 8 | 1,187
periodontitis 8 | 293
Brain Injuries 7 | 65
Breast Neoplasms 7 | 445
Chemical and Drug Induced Liver Injury 7 | 195
Coronary artery disease 7 | 268
Dermatitis 7 | 157
Inflammation 7 | 120
Kidney cancer 7 | 2,613
Mammary Neoplasms 7 | 425
Neoplasm Invasiveness 7 | 161
Peritonitis 7 | 43
Rheumatoid arthritis 7 | 1,191
Seizures 7 | 596
Vascular disease 7 | 319
astrocytoma 7 | 1,146
atypical teratoid / rhabdoid tumor 7 | 5,112
group 4 medulloblastoma 7 | 1,855
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
Allergic hypersensitivity disease 6 | 126
Alzheimer's disease 6 | 658
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Brain disease 6 | 96
Breast cancer 6 | 3,578
Encephalitis 6 | 64
Hyperglycemia 6 | 137
Immunologic Deficiency Syndromes 6 | 113
Leishmaniasis 6 | 47
Lung Neoplasms 6 | 232
Meningitis 6 | 67
Osteoporosis 6 | 363
adrenocortical carcinoma 6 | 1,428
dermatomyositis 6 | 966
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Arthritis, Rheumatoid 5 | 174
Duchenne muscular dystrophy 5 | 601
Endometriosis 5 | 540
Lipid metabolism disorder 5 | 114
Major Depressive Disorder 5 | 301
Multiple myeloma 5 | 1,332
Prostatic Neoplasms 5 | 495
Stomach Neoplasms 5 | 300
Unipolar Depression 5 | 250
Vasculitis 5 | 80
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
gastric carcinoma 5 | 807
head and neck cancer 5 | 271
mucosa-associated lymphoid tissue lymphoma 5 | 484
nasopharyngeal carcinoma 5 | 1,058

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Respiratory system 35 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 20 | 12,091
Kinase 9 | 634
Enzyme 6 | 4,145
Transcription Factor 2 | 1,400

WikiPathways Pathway

Fibrin Complement Receptor 3 S... 37 | 37
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras association domain-containing protein 5 RASSF5 Tbio Non-IDG -1.81149 71.3 155
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Integrin alpha-M ITGAM Tbio Non-IDG -3.63427 3939.5 2165
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Lipopolysaccharide-binding protein LBP Tbio Non-IDG -2.61682 357.2 225
Tissue-type plasminogen activator PLAT Tclin Enzyme -3.71677 5819.3 555
Interleukin-12 subunit beta IL12B Tclin Non-IDG -1.21064 19.3 675
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403