Development Level

Tchem 6 | 1,598
Tclin 6 | 613
Tbio 3 | 11,445

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49

Disease

Carcinoma 14 | 11,493
psoriasis 13 | 6,694
Cancer 10 | 2,499
Alcohol dependence 9 | 107
Alcoholic Intoxication, Chronic 9 | 289
Liver disease 9 | 237
Alcohol abuse 7 | 50
lung cancer 6 | 4,740
Schizophrenia 5 | 1,160
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
substance-related disorder 5 | 162
Alcoholic Intoxication 4 | 34
Alcoholism 4 | 45
Chemical and Drug Induced Liver Injury 4 | 195
Colorectal Neoplasms 4 | 243
Liver Cirrhosis, Experimental 4 | 769
Prostatic Neoplasms 4 | 495
Substance abuse 4 | 59
diabetes mellitus 4 | 1,728
esophageal cancer 4 | 22
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
nasopharyngeal carcinoma 4 | 1,058
osteosarcoma 4 | 7,950
tuberculosis 4 | 2,010
Accidental poisoning by methyl alcohol 3 | 3
Adverse reaction to drug 3 | 61
Attention deficit hyperactivity disorder 3 | 278
Breast Neoplasms 3 | 445
Drug-Related Side Effects and Adverse Reactions 3 | 62
Esophageal Neoplasms 3 | 69
Esophageal Squamous Cell Carcinoma 3 | 77
Ethylene Glycol Toxicity 3 | 3
Genetic Predisposition to Disease 3 | 27
Hepatitis C 3 | 94
Hypertension 3 | 396
Lung Neoplasms 3 | 232
Mammary Neoplasms 3 | 425
Mouth Neoplasms 3 | 55
Organ system cancer 3 | 18
Pancreatitis 3 | 123
Squamous cell carcinoma of esophagus 3 | 77
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
non-small cell lung carcinoma 3 | 317
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
Adenocarcinoma 2 | 122
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autoimmune hepatitis 2 | 11
Bradycardia 2 | 36
Breast cancer 2 | 3,578
Carcinoma, Hepatocellular 2 | 228
Cardiomegaly 2 | 116
Cholestasis 2 | 155
Chronic Obstructive Airway Disease 2 | 37
Coronary artery disease 2 | 268
Depressive Symptoms 2 | 28
Drug Eruptions 2 | 18
Essential Hypertension 2 | 94
Hepatomegaly 2 | 285
Infertility, Male 2 | 46
Kidney disease 2 | 430
Liver Neoplasms, Experimental 2 | 59
Liver carcinoma 2 | 240
Lung Injury 2 | 20
Malaria 2 | 160
Male infertility 2 | 206
Micronuclei, Chromosome-Defective 2 | 25
Non-alcoholic Fatty Liver Disease 2 | 42
Occupational Diseases 2 | 12
Pain agnosia 2 | 104
Parkinson Disease 2 | 64
Pulmonary Disease, Chronic Obstructive 2 | 31
Retinitis pigmentosa 23 2 | 27
Schizophrenia and related disorders 2 | 8
Succinic semialdehyde dehydrogenase deficiency 2 | 16
Wernicke-Korsakoff syndrome 2 | 10
adrenocortical adenoma 2 | 131
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
chronic rhinosinusitis 2 | 512
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
ulcerative colitis 2 | 1,819

Tissue

Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Male tissues 14 | 17,142
Respiratory system 14 | 16,393
Blood and immune system 13 | 16,909
Nervous System 10 | 16,725
Cardiovascular System 9 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 5 | 12,091

WikiPathways Pathway

Fatty Acid Omega Oxidation 15 | 15
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alcohol dehydrogenase class 4 mu/sigma chain ADH7 Tchem Enzyme -2.18765 159.0 243
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.97180 93.7 142
Alcohol dehydrogenase 6 ADH6 Tbio Enzyme -1.84121 71.7 117
Alcohol dehydrogenase 4 ADH4 Tbio Enzyme -2.30746 247.9 210
Cytochrome P450 2D6 CYP2D6 Tclin Enzyme -3.53105 3484.9 433
Retinal dehydrogenase 1 ALDH1A1 Tchem Enzyme -2.81062 648.3 725
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.65839 4688.0 397
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.54987 3641.5 384
Alcohol dehydrogenase 1B ADH1B Tclin Enzyme -2.42307 381.5 160
Alcohol dehydrogenase 1C ADH1C Tclin Enzyme -2.42307 381.5 97