Development Level

Tchem 12 | 1,598
Tbio 5 | 11,445
Tclin 4 | 613
Tdark 2 | 6,588

IMPC Phenotype

abnormal seminal vesicle morph... 1 | 114
decreased lymphocyte cell numb... 1 | 83
hydrometra 1 | 53
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
small superior vagus ganglion 1 | 74

Disease

Carcinoma 14 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 13 | 8,520
non-small cell lung cancer 11 | 2,890
Cancer 10 | 2,499
lung cancer 10 | 4,740
lung carcinoma 10 | 2,843
psoriasis 9 | 6,694
Asthma 8 | 385
Atherosclerosis 8 | 291
malignant mesothelioma 8 | 3,232
Hypertension 7 | 396
glioblastoma 7 | 5,792
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
Coronary artery disease 6 | 268
cystic fibrosis 6 | 1,696
group 3 medulloblastoma 6 | 4,104
invasive ductal carcinoma 6 | 2,951
ulcerative colitis 6 | 1,819
Arthritis 5 | 290
Bipolar Disorder 5 | 666
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
medulloblastoma, large-cell 5 | 6,241
primary pancreatic ductal adenocarcinoma 5 | 1,109
Actinic keratosis 4 | 21
Autosomal recessive predisposition 4 | 1,442
Cerebrovascular disease 4 | 238
Depressive disorder 4 | 409
Hyperalgesia 4 | 83
Kidney disease 4 | 430
Liver disease 4 | 237
Obesity 4 | 678
Osteoarthritis 4 | 184
Reperfusion Injury 4 | 86
Urticaria 4 | 67
adult high grade glioma 4 | 3,801
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
tuberculosis 4 | 2,010
Arthritis, Rheumatoid 3 | 174
Atopic dermatitis 3 | 952
Chronic ulcerative proctitis 3 | 7
Chronic ulcerative rectosigmoiditis 3 | 4
Common cold 3 | 67
Drug Hypersensitivity 3 | 34
Drug allergy 3 | 36
Dysmenorrhea 3 | 21
Endometriosis 3 | 540
Endometritis 3 | 21
Esophageal Neoplasms 3 | 69
Fatty liver disease 3 | 103
Fever 3 | 138
Hepatitis C 3 | 94
Juvenile rheumatoid arthritis 3 | 111
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Menorrhagia 3 | 25
Muscle hypotonia 3 | 571
Myocardial Infarction 3 | 151
Pain 3 | 103
Pancreatitis 3 | 123
Patent ductus arteriosus 3 | 90
Pleurisy 3 | 19
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Toxic encephalopathy 3 | 141
Ulcerative colitis in remission 3 | 4
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
pancreatic carcinoma 3 | 562
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735
subependymal giant cell astrocytoma 3 | 2,287
Colitis 2 | 54
Dysarthria 2 | 192
Dystonic disease 2 | 106
Hepatitis B 2 | 108
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hydronephrosis 2 | 89
Infantile onset 2 | 238
Inflammation 2 | 120
Liver diseases 2 | 87
Pain agnosia 2 | 104
Phenotypic variability 2 | 150
Progressive disorder 2 | 142

Tissue

Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Male tissues 23 | 17,142
Respiratory system 23 | 16,393
Urinary Tract 23 | 16,678
Female tissues 22 | 17,400
Blood and immune system 21 | 16,909
Liver and Pancreas 21 | 16,750
Nervous System 20 | 16,725
Skin and soft tissues 20 | 17,230
Cardiovascular System 19 | 15,192

Target Family

Enzyme 23 | 4,145

WikiPathways Pathway

Eicosanoid Synthesis 23 | 23
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inactive glutathione hydrolase 2 GGT2 Tbio Enzyme -3.09193 1683.2 62
Phospholipase A2, membrane associated PLA2G2A Tchem Enzyme -2.83666 743.3 137
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Leukotriene C4 synthase LTC4S Tchem Enzyme -1.98032 93.9 89
Calcium-independent phospholipase A2-gamma PNPLA8 Tbio Enzyme -1.96549 89.5 114
Prostaglandin E synthase PTGES Tchem Enzyme -3.05403 1164.2 151
Leukotriene A-4 hydrolase LTA4H Tchem Enzyme -2.11151 125.3 291
Prostacyclin synthase PTGIS Tchem Enzyme -2.55019 341.8 152
Arachidonate 12-lipoxygenase, 12S-type ALOX12 Tchem Enzyme -2.35458 223.8 137