Development Level

Tbio 5 | 11,445
Tclin 2 | 613

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
abnormal seminal vesicle morph... 1 | 114
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Cancer 6 | 2,499
medulloblastoma, large-cell 6 | 6,241
lung cancer 5 | 4,740
Carcinoma 4 | 11,493
Schizophrenia 4 | 1,160
diabetes mellitus 4 | 1,728
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
Atherosclerosis 3 | 291
Breast cancer 3 | 3,578
Endometriosis 3 | 540
Multiple Sclerosis 3 | 540
Polycystic ovary syndrome 3 | 360
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
Acquired immunodeficiency syndrome 2 | 197
Adenocarcinoma 2 | 122
Alzheimer's disease 2 | 658
Anemia 2 | 365
Arthritis 2 | 290
Asthma 2 | 385
Bipolar Disorder 2 | 666
Brain disease 2 | 96
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Depressive disorder 2 | 409
Dermatitis 2 | 157
Fever 2 | 138
Glioma 2 | 74
Heart disease 2 | 306
Heart failure 2 | 162
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Hypoglycemia 2 | 152
Hypotension 2 | 82
Infertility 2 | 188
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Lung diseases 2 | 50
Major Depressive Disorder 2 | 301
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Mood Disorders 2 | 184
Myocardial Infarction 2 | 151
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Nerve Degeneration 2 | 121
Obesity 2 | 678
Pain 2 | 103
Pregnancy Complications, Cardiovascular 2 | 4
Pulmonary Fibrosis 2 | 106
Rheumatoid arthritis 2 | 1,191
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
periodontitis 2 | 293
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Anxiety disorder 1 | 23
Asthma, Occupational 1 | 10
Colitis, Ulcerative 1 | 59
Compression of spinal cord 1 | 10
Craniopharyngioma 1 | 16
Cystitis 1 | 15
Degenerative disc disease 1 | 35
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Drug Hypersensitivity 1 | 34
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Hypothermia 1 | 12
Hypothermia, natural 1 | 17
Neurogenic Inflammation 1 | 12
Plaque psoriasis 1 | 17
Primary immunodeficiency disease 1 | 54
Psoriasis with arthropathy 1 | 11
Xerostomia 1 | 42

Tissue

Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Blood and immune system 6 | 16,909
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Cardiovascular System 5 | 15,192

Target Family

Non-IDG 4 | 12,091
Transcription Factor 2 | 1,400
Kinase 1 | 634

WikiPathways Pathway

EV release from cardiac cells ... 7 | 7
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.30630 216.2 308
Regulator of G-protein signaling 16 RGS16 Tbio Non-IDG -1.61831 43.3 185
Stromal cell-derived factor 1 CXCL12 Tbio Non-IDG -3.48446 3085.9 607
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
Transcriptional activator Myb MYB Tbio Transcription Factor -2.97697 938.9 642
Prolactin PRL Tbio Non-IDG -3.98498 10147.6 1281
Tumor necrosis factor TNF Tclin Non-IDG -4.71806 50345.6 2958