Development Level

Tbio 7 | 11,651
Tchem 1 | 1,388

Disease

ovarian cancer 8 | 8,520
Cancer 5 | 2,499
Carcinoma 4 | 11,493
osteosarcoma 4 | 7,950
Astrocytoma, Pilocytic 3 | 3,081
Multiple myeloma 3 | 1,332
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
glioblastoma 3 | 5,792
lung cancer 3 | 4,740
Amyotrophic lateral sclerosis 2 | 451
Breast cancer 2 | 3,578
Cleft Palate 2 | 271
Cleidocranial dysplasia 2 | 10
Down syndrome 2 | 499
Hemangioma 2 | 69
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Rheumatoid arthritis 2 | 1,191
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
chronic kidney disease 2 | 90
ependymoma 2 | 4,679
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Acquired immunodeficiency syndrome 1 | 197
Acute monocytic leukemia 1 | 13
Alzheimer's disease 1 | 658
Bleeding time prolonged 1 | 31
Bone Diseases, Developmental 1 | 27
Breast Neoplasms 1 | 445
COPD 1 | 118
Carcinoma, Renal Cell 1 | 124
Cleft uvula 1 | 27
Cockayne syndrome 1 | 60
Congenital Heart Defects 1 | 58
Decreased platelet count 1 | 111
Ecchymosis 1 | 66
Epilepsy 1 | 792
Epistaxis 1 | 43
Fatigue 1 | 182
Fever 1 | 138
Gingival Hyperplasia 1 | 34
Gingival Hypertrophy 1 | 34
Gingival Overgrowth 1 | 36
Globe disease 1 | 67
Heart Defects, Congenital 1 | 37
Hematologic cancer 1 | 12
Hepatitis B 1 | 108
Human immunodeficiency virus infectious disease 1 | 138
Hypoplastic myelodysplasia 1 | 18
Impaired platelet aggregation 1 | 8
Increased number of platelets 1 | 14
Increased tendency to bruise 1 | 66
Juvenile Myelomonocytic Leukemia 1 | 21
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelomonocytic, Juvenile 1 | 20
Leukocytosis 1 | 17
Liver cancer 1 | 604
Lymphoma 1 | 81
MYELODYSPLASTIC SYNDROME 1 | 53
Mammary Neoplasms 1 | 425
Myelodysplastic Syndromes 1 | 26
Myeloproliferative disease 1 | 16
Myofibrillar myopathy 1 1 | 6
Myofibrillar myopathy 3 1 | 5
Neuroblastoma 1 | 80
Pick's disease 1 | 15
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1 | 12
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Renal Cell Carcinoma 1 | 214
Seizures 1 | 596
Stevens-Johnson syndrome 1 | 92
Submucous cleft of hard palate 1 | 11
Thrombocytopenia 1 | 197
Thrombocytosis 1 | 38
active Crohn's disease 1 | 922
adrenocortical carcinoma 1 | 1,428
colon cancer 1 | 1,478
dermatomyositis 1 | 966
esophageal cancer 1 | 22
fibroadenoma 1 | 559
inflammatory breast cancer 1 | 286
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
progressive supranuclear palsy 1 | 676
tuberculosis and treatment for 3 months 1 | 179
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 5 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

WikiPathways Pathway

Dual hijack model of Vif in HI... 8 | 8
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Runt-related transcription factor 1 RUNX1 Tbio Transcription Factor -3.25790 1899.3 798
DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G Tbio Non-IDG -2.78510 662.2 477
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Cullin-5 CUL5 Tbio Non-IDG -1.95870 91.8 188
E3 ubiquitin-protein ligase RBX1 RBX1 Tbio Enzyme -1.94266 72.1 260
Elongin-C ELOC Tbio Non-IDG -1.76876 49.5 154
Elongin-B ELOB Tbio Non-IDG -1.68021 35.1 251
Core-binding factor subunit beta CBFB Tchem Transcription Factor -0.78193 5.82 291