Development Level

Tclin 6 | 613
Tchem 4 | 1,598
Tbio 3 | 11,445

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal behavior 1 | 298
abnormal locomotor behavior 1 | 24
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased pulmonary respirator... 1 | 5
hyperactivity 1 | 148
increased circulating alanine ... 1 | 13
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
psoriasis 9 | 6,694
Parkinson's disease 8 | 392
Schizophrenia 8 | 1,160
ovarian cancer 8 | 8,520
Bipolar Disorder 6 | 666
Depressive disorder 6 | 409
medulloblastoma, large-cell 6 | 6,241
Alcoholic Intoxication, Chronic 5 | 289
Autosomal recessive predisposition 5 | 1,442
Major Depressive Disorder 5 | 301
Mental Depression 5 | 333
Mood Disorders 5 | 184
Parkinson Disease 5 | 64
Pheochromocytoma 5 | 24
Toxic encephalopathy 5 | 141
Unipolar Depression 5 | 250
atypical teratoid / rhabdoid tumor 5 | 5,112
lung adenocarcinoma 5 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Attention deficit hyperactivity disorder 4 | 278
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Hypotension 4 | 82
Multiple myeloma 4 | 1,332
adult high grade glioma 4 | 3,801
aldosterone-producing adenoma 4 | 665
glioblastoma 4 | 5,792
Alcohol dependence 3 | 107
Alzheimer's disease 3 | 658
Asthma 3 | 385
Autistic Disorder 3 | 364
Blepharoptosis 3 | 231
Dementia 3 | 175
Endometriosis 3 | 540
Hypertension 3 | 396
Mental disorders 3 | 12
Mood swings 3 | 77
Nerve Degeneration 3 | 121
Prostatic Neoplasms 3 | 495
Psychotic Disorders 3 | 151
Waldenstrons macroglobulinemia 3 | 765
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Acne 2 | 52
Axial hypotonia 2 | 46
Brain disease 2 | 96
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Cholangiocarcinoma 2 | 35
Cocaine Dependence 2 | 51
Cognition Disorders 2 | 32
Conduct disorder 2 | 33
Constipation 2 | 181
Contact Dermatitis 2 | 81
Dermatitis, Contact 2 | 71
Diabetes Mellitus, Experimental 2 | 108
Down syndrome 2 | 499
Dyschezia 2 | 135
Dystonia 2 | 164
Fatigue 2 | 182
Hepatic encephalopathy 2 | 27
Heroin dependence 2 | 30
Huntington Disease 2 | 13
Hyperreflexia 2 | 209
Hypertensive disorder 2 | 56
Infantile onset 2 | 238
Liver carcinoma 2 | 240
Liver diseases 2 | 87
Mammary Neoplasms 2 | 425
Muscle Weakness 2 | 170
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Norrie disease 2 | 14
Pain 2 | 103
Parkinsonian Disorders 2 | 56
Skeletal muscle atrophy 2 | 139
Sudden infant death syndrome 2 | 32
Vascular disease 2 | 319
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
muscle degeneration 2 | 139
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
pituitary cancer 2 | 1,972
tuberculosis and treatment for 6 months 2 | 409

Tissue

Endocrine System 13 | 18,159
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Skin and soft tissues 12 | 17,230
Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Liver and Pancreas 11 | 16,750
Nervous System 11 | 16,725
Urinary Tract 11 | 16,678
Respiratory system 10 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Enzyme 10 | 4,145
Kinase 3 | 634

WikiPathways Pathway

Dopamine metabolism 13 | 13
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NAD(P)H dehydrogenase [quinone] 1 NQO1 Tchem Enzyme -3.12097 1326.4 550
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Tyrosinase TYR Tclin Enzyme -3.32888 2021.2 494
Aromatic-L-amino-acid decarboxylase DDC Tclin Enzyme -2.78263 593.3 412
Catechol O-methyltransferase COMT Tclin Enzyme -3.46304 2976.1 433
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB Tbio Enzyme -1.13726 11.3 290
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA Tchem Enzyme -2.14505 119.6 506
Tyrosine 3-monooxygenase TH Tclin Enzyme -3.49790 2144.6 1203