Development Level

Tbio 11 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
decreased caudal vertebrae num... 1 | 53
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Cancer 11 | 2,499
osteosarcoma 8 | 7,950
psoriasis 8 | 6,694
Carcinoma 7 | 11,493
Rheumatoid arthritis 7 | 1,191
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
ovarian cancer 5 | 8,520
ulcerative colitis 5 | 1,819
Leukemia, Myelocytic, Acute 4 | 120
Leukemia, Myeloid, Acute 4 | 105
Lymphoid leukemia 4 | 160
adult high grade glioma 4 | 3,801
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
Arthritis, Rheumatoid 3 | 174
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Celiac disease 3 | 116
Coarse facial features 3 | 108
Crohn's disease 3 | 321
Fever 3 | 138
Liver Cirrhosis, Experimental 3 | 769
Liver neoplasms 3 | 130
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Short stature 3 | 531
Thickened facial skin with coarse facial features 3 | 108
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
medulloblastoma, large-cell 3 | 6,241
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Adult T-Cell Lymphoma/Leukemia 2 | 30
Anemia 2 | 365
Arthritis 2 | 290
Asthma 2 | 385
Atherosclerosis 2 | 291
Autoimmune Diseases 2 | 67
Bipolar Disorder 2 | 666
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Chronic Lymphocytic Leukemia 2 | 262
Chronic otitis media 2 | 52
Constipation 2 | 181
Craniofacial Abnormalities 2 | 151
Curvature of spine 2 | 282
Dermatitis 2 | 157
Duchenne muscular dystrophy 2 | 601
Dyschezia 2 | 135
Fatigue 2 | 182
Frontal bossing 2 | 157
Hypersensitivity reaction type II disease 2 | 253
Immune system cancer 2 | 140
Infantile onset 2 | 238
Inflammation 2 | 120
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Large bregma sutures 2 | 46
Large fontanelle 2 | 46
Large, late-closing fontanelle 2 | 46
Nasal bridge wide 2 | 236
Osteoporosis 2 | 363
Pneumonia 2 | 174
Recurrent respiratory infections 2 | 141
Schizophrenia 2 | 1,160
Short philtrum 2 | 53
Skin cancer 2 | 469
Systemic lupus erythematosus 2 | 194
Vascular disease 2 | 319
Waldenstrons macroglobulinemia 2 | 765
Wide bregma sutures 2 | 46
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
ear infection chronic 2 | 52
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Nervous System 12 | 16,725

Target Family

Transcription Factor 9 | 1,400
Enzyme 2 | 4,145
Non-IDG 2 | 12,091

WikiPathways Pathway

Development of pulmonary dendr... 13 | 13
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Interferon regulatory factor 4 IRF4 Tbio Transcription Factor -2.54787 365.3 532
Fms-related tyrosine kinase 3 ligand FLT3LG Tbio Enzyme -2.31017 235.2 270
Thyroid peroxidase TPO Tclin Enzyme -2.83776 580.4 368
Interferon regulatory factor 8 IRF8 Tbio Transcription Factor -2.37977 273.3 336
Granulocyte-macrophage colony-stimulating factor CSF2 Tbio Non-IDG -3.91682 8450.3 1272
DNA-binding protein Ikaros IKZF1 Tbio Transcription Factor -2.66732 483.6 400
Transcription factor 4 TCF4 Tbio Transcription Factor -2.57908 320.1 249
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749