Development Level

Tbio 22 | 11,445
Tclin 8 | 613
Tchem 2 | 1,598

IMPC Phenotype

decreased vertical activity 3 | 208
enlarged heart 3 | 210
abnormal heart morphology 2 | 162
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased or absent threshold ... 2 | 101
preweaning lethality, complete... 2 | 979
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
abnormal urinary bladder morph... 1 | 11
absent startle reflex 1 | 24
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating creatini... 1 | 39
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
short tibia 1 | 97
small thymus 1 | 16
vertebral fusion 1 | 23

Disease

Cancer 22 | 2,499
psoriasis 20 | 6,694
Asthma 18 | 385
Inflammatory bowel disease 16 | 151
lung cancer 15 | 4,740
Carcinoma 14 | 11,493
Hypereosinophilic syndrome 14 | 71
Hypersensitivity reaction type II disease 14 | 253
malignant mesothelioma 14 | 3,232
osteosarcoma 14 | 7,950
Allergic hypersensitivity disease 13 | 126
Breast cancer 13 | 3,578
Multiple Sclerosis 13 | 540
Rheumatoid arthritis 13 | 1,191
Allergic rhinitis 12 | 94
Arthritis 12 | 290
Dermatitis 12 | 157
tuberculosis 12 | 2,010
diabetes mellitus 11 | 1,728
Inflammation 10 | 120
Pneumonia 10 | 174
cutaneous lupus erythematosus 10 | 1,057
glioblastoma 10 | 5,792
interstitial cystitis 10 | 2,312
ulcerative colitis 10 | 1,819
Arthritis, Experimental 9 | 39
Chemical and Drug Induced Liver Injury 9 | 195
Common cold 9 | 67
Leishmaniasis 9 | 47
Lung disease 9 | 142
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
sarcoidosis 9 | 370
Arthritis, Rheumatoid 8 | 174
Astrocytoma, Pilocytic 8 | 3,081
Dermatitis, Atopic 8 | 37
Hepatitis, Autoimmune 8 | 17
Hypersensitivity 8 | 63
Pulmonary Fibrosis 8 | 106
Schizophrenia 8 | 1,160
Vasculitis 8 | 80
adult high grade glioma 8 | 3,801
cystic fibrosis 8 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung adenocarcinoma 8 | 2,716
periodontitis 8 | 293
Atherosclerosis 7 | 291
Autistic Disorder 7 | 364
Candidiasis 7 | 55
Colitis 7 | 54
Collagen disease 7 | 27
Influenza 7 | 142
Kidney disease 7 | 430
Major Depressive Disorder 7 | 301
Malaria 7 | 160
Parasitic helminthiasis infectious disease 7 | 15
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
pituitary cancer 7 | 1,972
Anemia 6 | 365
Bipolar Disorder 6 | 666
Breast Neoplasms 6 | 445
Diarrhea 6 | 253
Endometriosis 6 | 540
Fever 6 | 138
Liver Cirrhosis, Experimental 6 | 769
Liver disease 6 | 237
Mammary Neoplasms 6 | 425
Mental Depression 6 | 333
Necrosis 6 | 53
Primary immunodeficiency disease 6 | 54
Stomach Neoplasms 6 | 300
Tetanus 6 | 68
Unipolar Depression 6 | 250
colon cancer 6 | 1,478
Abortion, Spontaneous 5 | 109
Acquired immunodeficiency syndrome 5 | 197
Atopic dermatitis 5 | 952
Brain Ischemia 5 | 110
Coronary artery disease 5 | 268
Depressive disorder 5 | 409
Dermatitis, Allergic Contact 5 | 67
Heart disease 5 | 306
Hepatitis B 5 | 108
Hypertension 5 | 396
Meningitis 5 | 67
Neoplasm Invasiveness 5 | 161
Neuropathy 5 | 261
Respiratory Hypersensitivity 5 | 19
Spontaneous abortion 5 | 113
Uveitis 5 | 103
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
mucosa-associated lymphoid tissue lymphoma 5 | 484
subependymal giant cell astrocytoma 5 | 2,287

Tissue

Skin and soft tissues 32 | 17,230
Digestive Tract 31 | 17,369
Urinary Tract 31 | 16,678
Blood and immune system 30 | 16,909
Endocrine System 30 | 18,159
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Female tissues 28 | 17,400
Respiratory system 28 | 16,393
Nervous System 27 | 16,725
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 20 | 12,091
Transcription Factor 11 | 1,400
Nuclear Receptor 1 | 48

WikiPathways Pathway

Development and heterogeneity ... 32 | 32
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176
Thymocyte selection-associated high mobility group box protein TOX TOX Tbio Transcription Factor -2.98637 953.0 77
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Aryl hydrocarbon receptor AHR Tchem Transcription Factor 0.00000 773
Thymic stromal lymphopoietin TSLP Tbio Non-IDG -2.78236 713.0 495
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Interleukin-5 IL5 Tclin Non-IDG -3.45852 2701.9 571
Zinc finger and BTB domain-containing protein 16 ZBTB16 Tbio Transcription Factor -2.31797 210.0 275