Development Level

Tbio 14 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal sleep behavior 1 | 70
decreased hemoglobin content 1 | 68
decreased vertical activity 1 | 208
increased hematocrit 1 | 46

Disease

Carcinoma 13 | 11,493
osteosarcoma 11 | 7,950
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 9 | 4,679
glioblastoma 9 | 5,792
Astrocytoma, Pilocytic 8 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
medulloblastoma, large-cell 8 | 6,241
oligodendroglioma 8 | 2,850
pancreatic cancer 8 | 2,398
Griscelli syndrome 7 | 24
adult high grade glioma 7 | 3,801
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung carcinoma 7 | 2,843
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
pituitary cancer 6 | 1,972
group 3 medulloblastoma 5 | 4,104
nasopharyngeal carcinoma 5 | 1,058
ovarian cancer 5 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Pick disease 4 | 1,894
active ulcerative colitis 4 | 764
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Breast cancer 3 | 3,578
Chediak-Higashi syndrome 3 | 26
Kidney cancer 3 | 2,613
active Crohn's disease 3 | 922
fibroadenoma 3 | 559
Autosomal recessive predisposition 2 | 1,442
Choroideremia 2 | 16
Griscelli syndrome type 2 2 | 12
Griscelli syndrome type 3 2 | 13
Hemophagocytic lymphohistiocytosis 2 | 30
Oculocutaneous albinism 2 | 29
Pancytopenia 2 | 45
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
pediatric high grade glioma 2 | 1,064
Acquired metabolic disease 1 | 336
Alzheimer's disease 1 | 658
Azoospermia 1 | 110
Disease of anatomical entity 1 | 32
Down syndrome 1 | 499
Endometriosis 1 | 540
Epilepsy 1 | 792
Frontotemporal dementia 1 | 51
Hepatomegaly 1 | 285
Hermansky-Pudlak syndrome 1 | 42
Hyperkeratosis 1 | 50
Hyperlipidemia 1 | 43
Hypertrophy of breast 1 | 17
Hypopigmentation disorder 1 | 25
Icterus 1 | 82
Immunologic Deficiency Syndromes 1 | 113
Increased susceptibility to bacterial infections 1 | 42
Infantile onset 1 | 238
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Lymphadenopathy 1 | 62
Lymphoid leukemia 1 | 160
Muscle Spasticity 1 | 195
Neutrophil count decreased 1 | 47
Ocular albinism 1 | 26
Platelet storage pool deficiency 1 | 21
Prone to bacterial infection 1 | 42
Prostate cancer 1 | 175
Recurrent bacterial infection 1 | 42
Seizures 1 | 596
Type 2 diabetes mellitus 1 | 272
adrenocortical adenoma 1 | 131
aldosterone-producing adenoma 1 | 665
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,696
esophageal adenocarcinoma 1 | 737
facioscapulohumeral dystrophy 1 | 288
glioblastoma multiforme 1 | 142
head and neck cancer 1 | 271
medulloblastoma 1 | 720
pancreatic carcinoma 1 | 562
posterior fossa group A ependymoma 1 | 468
primary pancreatic ductal adenocarcinoma 1 | 1,109
sonic hedgehog group medulloblastoma 1 | 467
urothelial carcinoma 1 | 318

Tissue

Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242

WikiPathways Pathway

Deregulation of Rab and Rab Ef... 16 | 16
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-27A RAB27A Tchem Enzyme -2.30319 204.9 308
Rabphilin-3A RPH3A Tbio Epigenetic -1.78352 69.1 198
Ras-related protein Rab-27B RAB27B Tbio Enzyme -1.63479 44.7 179
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.93790 85.1 158
Rab effector Noc2 RPH3AL Tbio Non-IDG -1.26757 23.0 148
GRIP and coiled-coil domain-containing protein 2 GCC2 Tbio Non-IDG -1.05613 12.1 143
Melanophilin MLPH Tbio Non-IDG -1.57425 39.8 142
Rab effector MyRIP MYRIP Tbio Non-IDG -1.04097 13.1 128
MAP kinase-activating death domain protein MADD Tbio Enzyme -1.86555 79.6 121
Synaptotagmin-like protein 4 SYTL4 Tbio Non-IDG -1.22383 18.7 112