Development Level

Tbio 1 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

Disease

glioblastoma 3 | 5,792
ovarian cancer 3 | 8,520
Autosomal recessive predisposition 2 | 1,442
Carcinoma 2 | 11,493
Coarse facial features 2 | 108
Congestive heart failure 2 | 113
Corneal Opacity 2 | 53
Epilepsy 2 | 792
Fabry disease 2 | 11
Gangliosidosis 2 | 20
Heart failure 2 | 162
Optic Atrophy 2 | 242
Seizures 2 | 596
Short stature 2 | 531
Thickened facial skin with coarse facial features 2 | 108
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
inclusion-cell disease 2 | 16
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormality of the face 1 | 10
Abnormality of the renal tubule 1 | 7
Abnormality of the spleen 1 | 13
Abnormality of the urinary system 1 | 21
Actual Aspiration 1 | 8
Anorexia 1 | 43
Aortic valve stenosis 1 | 28
Apathy 1 | 16
Atrioventricular block 1 | 35
Atrioventricular nodal disease 1 | 10
Beaked vertebral bodies 1 | 9
Bone Diseases, Developmental 1 | 27
Bullet vertebral body 1 | 17
Bundle-Branch Block 1 | 8
Cervical myelopathy 1 | 6
Cervical subluxation 1 | 2
Cherry red spot of the macula 1 | 7
Cloudy cornea 1 | 33
Constricted iliac wings 1 | 2
Corneal stromal opacities 1 | 33
Delayed Puberty 1 | 97
Developmental arrest 1 | 4
Disorder of face 1 | 10
Exaggerated acoustic startle response 1 | 8
Exaggerated startle response 1 | 8
Fabry's disease 1 | 2
Flared iliac wings 1 | 13
Flaring of rib cage 1 | 2
Full lower lip 1 | 64
Gangliosidosis GM1 1 | 4
Glycoproteinosis 1 | 12
Gm2-ganglioside accumulation 1 | 2
Grayish enamel 1 | 2
Hand deformities 1 | 32
Hematuria 1 | 36
Hyperexplexia 1 | 8
Hyperkyphosis 1 | 111
Hypertrichosis 1 | 46
Hypoplastic acetabulae 1 | 3
Hypoplastic vertebral bodies 1 | 7
Increased startle response 1 | 8
Joint laxity 1 | 54
Keratan sulfate excretion in urine 1 | 3
Kyphosis deformity of spine 1 | 114
Lordosis 1 | 54
Lung Diseases, Obstructive 1 | 4
Metaphyseal widening 1 | 22
Mild Mental Retardation 1 | 70
Mitral regurgitation, mild 1 | 32
Mucopolysaccharidosis IV 1 | 5
Multiple, subcutaneous nodules 1 | 53
Muscle Cramp 1 | 55
Myalgia 1 | 54
Nausea 1 | 20
Nephrotic Syndrome 1 | 78
Niemann-Pick disease 1 | 14
ODONTOID HYPOPLASIA 1 | 16
Ovoid vertebral bodies 1 | 17
Platyspondyly 1 | 56
Poor head control 1 | 14
Prominent lower lip 1 | 64
Prominent sternum 1 | 4
Pulmonary aspiration 1 | 8
Pulmonary emphysema 1 | 48
Restrictive lung disease 1 | 11
Restrictive ventilatory defect 1 | 11
Rotting teeth 1 | 73
Sandhoff disease 1 | 3
Sea-Blue Histiocyte Syndrome 1 | 7
Short-trunked dwarfism 1 | 13
Slurred speech 1 | 7
Subcutaneous nodule 1 | 53
Tay-Sachs Disease, AB Variant 1 | 1
Tay-Sachs disease 1 | 6
Tay-Sachs disease AB variant 1 | 1
Ulnar deviation of the wrist 1 | 8
VALVULAR ABNORMALITY 1 | 12
Vacuolated lymphocytes 1 | 8
Wedging of vertebra 1 | 9
Widely spaced teeth 1 | 31

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 2 | 4,145
Non-IDG 1 | 12,091

WikiPathways Pathway

Degradation pathway of sphingo... 3 | 3
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-galactosidase A GLA Tclin Enzyme -3.00418 985.0 249
Ganglioside GM2 activator GM2A Tbio Non-IDG -2.03952 111.9 325
Beta-galactosidase GLB1 Tchem Enzyme -2.66211 439.4 477