Development Level

Tbio 15 | 10,625
Tchem 14 | 1,890
Tclin 3 | 602

IMPC Term

decreased total body fat amoun... 2 | 186
abnormal behavioral response t... 1 | 52
abnormal snout morphology 1 | 18
decreased caudal vertebrae num... 1 | 49
decreased circulating choleste... 1 | 85
decreased fasted circulating g... 1 | 49
decreased mean corpuscular hem... 1 | 34
increased circulating bilirubi... 1 | 16
increased grip strength 1 | 83
increased kidney weight 1 | 4
increased lean body mass 1 | 107
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

Cancer 22 | 2,346
psoriasis 18 | 6,685
ovarian cancer 15 | 8,484
osteosarcoma 13 | 7,933
lung cancer 12 | 4,466
medulloblastoma, large-cell 12 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
atypical teratoid / rhabdoid tumor 10 | 4,369
glioblastoma 10 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
Prostatic Neoplasms 9 | 471
Bilirubin metabolic disorder 8 | 39
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
lung adenocarcinoma 8 | 2,713
Drug-Induced Liver Injury 7 | 118
diabetes mellitus 7 | 1,663
Carcinoma 6 | 2,147
Cholestasis 6 | 93
Liver disease 6 | 219
interstitial cystitis 6 | 2,299
Breast cancer 5 | 3,094
Epilepsy 5 | 346
Mammary Neoplasms 5 | 410
Neutropenia 5 | 78
Rheumatoid Arthritis 5 | 1,160
adult high grade glioma 5 | 2,148
invasive ductal carcinoma 5 | 2,950
malignant mesothelioma 5 | 3,162
ulcerative colitis 5 | 2,087
Acute kidney injury 4 | 65
Adverse reaction to drug 4 | 54
Anemia 4 | 252
Colorectal Neoplasms 4 | 217
Neoplasm Metastasis 4 | 138
Obesity 4 | 616
Peripheral Neuropathy 4 | 303
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,157
aldosterone-producing adenoma 4 | 664
astrocytoma 4 | 1,493
group 3 medulloblastoma 4 | 2,254
lung carcinoma 4 | 2,844
non primary Sjogren syndrome sicca 4 | 840
pituitary cancer 4 | 1,972
tuberculosis 4 | 1,557
Contact Dermatitis 3 | 80
Diarrhea 3 | 155
Disease Progression 3 | 125
Endometriosis 3 | 535
Fatty liver disease 3 | 84
Hyperglycemia 3 | 120
Hypertension 3 | 287
Liver Cirrhosis, Experimental 3 | 108
Metabolic syndrome X 3 | 155
Multiple myeloma 3 | 1,327
Neonatal jaundice 3 | 15
Pericholangitis 3 | 7
Schizophrenia 3 | 501
Vascular disease 3 | 281
active Crohn's disease 3 | 918
adrenocortical carcinoma 3 | 1,427
dermatomyositis 3 | 933
ependymoma 3 | 2,514
group 4 medulloblastoma 3 | 1,875
nephrosclerosis 3 | 329
nervous system disorder 3 | 53
non-small cell lung carcinoma 3 | 413
pancreatic cancer 3 | 2,300
pediatric high grade glioma 3 | 2,712
primitive neuroectodermal tumor 3 | 3,031
Acute intermittent porphyria 2 | 14
Atrial Fibrillation 2 | 110
Congenital adrenal hyperplasia 2 | 74
Coronary artery disease 2 | 240
Drug allergy 2 | 36
HIV Infections 2 | 100
Hepatitis C 2 | 90
Nicotine dependence 2 | 53
Pick disease 2 | 1,893
Sickle cell anemia 2 | 35
Squamous cell carcinoma of esophagus 2 | 82
Squamous cell carcinoma of the head and neck 2 | 24
Stomach Neoplasms 2 | 282
Thalassemia 2 | 46
Toxic encephalopathy 2 | 131
astrocytic glioma 2 | 2,241
colon cancer 2 | 1,475
cutaneous lupus erythematosus 2 | 1,056
cystic fibrosis 2 | 1,665
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 832
juvenile dermatomyositis 2 | 1,189
medulloblastoma 2 | 1,524
mucosa-associated lymphoid tissue lymphoma 2 | 480
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
primary pancreatic ductal adenocarcinoma 2 | 1,271

Tissue

Digestive Tract 32 | 18,473
Liver and Pancreas 32 | 18,136
Urinary Tract 32 | 18,444
Blood and immune system 31 | 17,995
Female tissues 30 | 18,647
Nervous System 30 | 18,561
Skin and soft tissues 30 | 18,115
Endocrine System 29 | 18,512
Male tissues 29 | 17,969
Cardiovascular System 28 | 17,958
Respiratory system 28 | 17,484

Target Family

Enzyme 12 | 4,146
Non-IDG 12 | 11,971
Transporter 3 | 473
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

WikiPathways Pathway

Constitutive Androstane Recept... 32 | 32
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Canalicular multispecific organic anion transporter 2 ABCC3 Tbio Transporter -2.43175 279.8 196
Sulfotransferase 1A1 SULT1A1 Tchem Enzyme -2.49044 330.9 248
5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 Tbio Enzyme -1.74695 57.8 136
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -2.96006 1000.8 1343
Nuclear receptor subfamily 1 group I member 3 NR1I3 Tchem Nuclear Receptor -2.51708 258.1 278
DnaJ homolog subfamily C member 7 DNAJC7 Tbio Non-IDG -1.22263 13.9 147
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.93234 88.7 122
Peroxisomal bifunctional enzyme EHHADH Tbio Non-IDG -2.00791 101.2 161
Cytochrome P450 2C19 CYP2C19 Tchem Non-IDG -3.17457 1627.4 145
Transcription factor Sp1 SP1 Tchem Transcription Factor -2.97850 923.1 729