Development Level

Tbio 20 | 11,651
Tchem 9 | 1,388
Tclin 3 | 612

IMPC Phenotype

decreased total body fat amoun... 3 | 207
decreased mean corpuscular hem... 2 | 50
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased vertical activity 1 | 208
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased circulating bilirubi... 1 | 16
increased grip strength 1 | 41
increased kidney weight 1 | 6
male infertility 1 | 123

Disease

Carcinoma 28 | 11,493
Cancer 22 | 2,499
psoriasis 18 | 6,694
ovarian cancer 15 | 8,520
lung cancer 14 | 4,740
osteosarcoma 13 | 7,950
medulloblastoma, large-cell 12 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 10 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Chemical and Drug Induced Liver Injury 9 | 195
Kidney cancer 9 | 2,613
Prostatic Neoplasms 9 | 495
Bilirubin metabolic disorder 8 | 41
Liver disease 8 | 237
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung adenocarcinoma 8 | 2,716
diabetes mellitus 7 | 1,728
Cholestasis 6 | 155
Epilepsy 6 | 792
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
adult high grade glioma 6 | 3,801
interstitial cystitis 6 | 2,312
malignant mesothelioma 6 | 3,232
Breast Neoplasms 5 | 445
Breast cancer 5 | 3,578
Mammary Neoplasms 5 | 425
Neutropenia 5 | 72
Sickle Cell Anemia 5 | 53
group 3 medulloblastoma 5 | 4,104
invasive ductal carcinoma 5 | 2,951
ulcerative colitis 5 | 1,819
Acute kidney injury 4 | 70
Adverse reaction to drug 4 | 61
Anemia 4 | 365
Autosomal recessive predisposition 4 | 1,442
Colorectal Neoplasms 4 | 243
Diarrhea 4 | 253
Drug-Related Side Effects and Adverse Reactions 4 | 62
Liver Cirrhosis, Experimental 4 | 769
Major Depressive Disorder 4 | 301
Neoplasm Metastasis 4 | 168
Obesity 4 | 678
Unipolar Depression 4 | 250
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
ependymoma 4 | 4,679
lung carcinoma 4 | 2,843
non primary Sjogren syndrome sicca 4 | 891
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Arthritis, Rheumatoid 3 | 174
Atrial Fibrillation 3 | 124
Bipolar Disorder 3 | 666
Contact Dermatitis 3 | 81
Depressive disorder 3 | 409
Dermatitis, Contact 3 | 71
Disease Progression 3 | 136
Endometriosis 3 | 540
Fatty liver disease 3 | 103
Hyperglycemia 3 | 137
Hypertension 3 | 396
Malaria 3 | 160
Melanoma 3 | 711
Multiple myeloma 3 | 1,332
Neonatal Jaundice 3 | 30
Nervous System Diseases 3 | 53
Pericholangitis 3 | 8
Psychotic Disorders 3 | 151
Vascular disease 3 | 319
active Crohn's disease 3 | 922
adrenocortical carcinoma 3 | 1,428
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
nephrosclerosis 3 | 333
nervous system disorder 3 | 53
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
Abnormality of blood and blood-forming tissues 2 | 10
Abnormality of the haematopoietic system 2 | 10
Acute intermittent porphyria 2 | 15
Coronary artery disease 2 | 268
Cushing's syndrome 2 | 48
Endometrial cancer 2 | 311
Gastroesophageal reflux disease 2 | 110
Hematological Disease 2 | 18
Hepatomegaly 2 | 285
Stomach Neoplasms 2 | 300
Toxic encephalopathy 2 | 141
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
medulloblastoma 2 | 720
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416

Tissue

Liver and Pancreas 32 | 16,750
Digestive Tract 31 | 17,369
Skin and soft tissues 31 | 17,230
Male tissues 30 | 17,142
Urinary Tract 30 | 16,678
Female tissues 28 | 17,400
Endocrine System 27 | 18,159
Respiratory system 27 | 16,393
Blood and immune system 26 | 16,909
Nervous System 26 | 16,725
Cardiovascular System 20 | 15,192

Target Family

Enzyme 12 | 4,145
Non-IDG 12 | 12,091
Transporter 3 | 473
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

WikiPathways Pathway

Constitutive Androstane Recept... 32 | 32
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear receptor subfamily 1 group I member 3 NR1I3 Tchem Nuclear Receptor -2.57140 281.2 304
DnaJ homolog subfamily C member 7 DNAJC7 Tbio Non-IDG -1.27895 15.9 163
Sulfotransferase 1A1 SULT1A1 Tbio Enzyme -2.48197 334.8 278
Cytochrome P450 2C9 CYP2C9 Tchem Non-IDG -3.21210 1623.8 177
Transcription factor Sp1 SP1 Tbio Transcription Factor -3.01541 976.7 780
UDP-glucuronosyltransferase 1-4 UGT1A4 Tbio Enzyme -1.80749 62.9 59
Cytochrome P450 2A6 CYP2A6 Tchem Non-IDG -2.84002 705.5 272
Glutathione S-transferase A2 GSTA2 Tbio Enzyme -1.86602 68.2 165
Nuclear receptor coactivator 2 NCOA2 Tbio Non-IDG -2.17388 142.6 197
Canalicular multispecific organic anion transporter 2 ABCC3 Tbio Transporter -2.46032 287.4 214