Development Level

Tbio 35 | 11,445
Tchem 16 | 1,598
Tclin 8 | 613

IMPC Phenotype

abnormal behavior 2 | 298
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
decreased mean corpuscular vol... 2 | 79
enlarged heart 2 | 210
increased circulating sodium l... 2 | 71
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal placement of pupils 1 | 6
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
increased aggression 1 | 4
increased bone mineral content 1 | 108
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
polycystic kidney 1 | 15
shortened RR interval 1 | 17
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 49 | 11,493
ovarian cancer 35 | 8,520
lung cancer 31 | 4,740
lung carcinoma 31 | 2,843
Autosomal recessive predisposition 30 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,962
invasive ductal carcinoma 27 | 2,951
psoriasis 27 | 6,694
Cancer 26 | 2,499
non-small cell lung cancer 25 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
glioblastoma 23 | 5,792
lung adenocarcinoma 23 | 2,716
ulcerative colitis 22 | 1,819
Astrocytoma, Pilocytic 21 | 3,081
Kidney disease 20 | 430
interstitial cystitis 20 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
malignant mesothelioma 20 | 3,232
tuberculosis 18 | 2,010
Breast cancer 17 | 3,578
Cerebrovascular disease 17 | 238
adult high grade glioma 17 | 3,801
ependymoma 17 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
pancreatic cancer 17 | 2,398
Coronary artery disease 16 | 268
Pulmonary embolism 16 | 55
diabetes mellitus 16 | 1,728
Atherosclerosis 15 | 291
Disseminated intravascular coagulation 15 | 38
Thrombophilia 15 | 38
adrenocortical carcinoma 15 | 1,428
atypical teratoid / rhabdoid tumor 15 | 5,112
cystic fibrosis 15 | 1,696
medulloblastoma, large-cell 15 | 6,241
Liver Cirrhosis, Experimental 14 | 769
Thrombocytopenia 14 | 197
Thrombosis 14 | 46
Vascular disease 14 | 319
group 3 medulloblastoma 14 | 4,104
osteosarcoma 14 | 7,950
Atopic dermatitis 13 | 952
Hypertension 13 | 396
Venous Thrombosis 13 | 47
breast carcinoma 13 | 1,638
subependymal giant cell astrocytoma 13 | 2,287
Kidney cancer 12 | 2,613
colon cancer 12 | 1,478
Complement deficiency 11 | 14
Duchenne muscular dystrophy 11 | 601
Liver disease 11 | 237
acute quadriplegic myopathy 11 | 1,158
ductal carcinoma in situ 11 | 1,745
pituitary cancer 11 | 1,972
Anemia 10 | 365
Protein C deficiency 10 | 19
Systemic lupus erythematosus 10 | 194
dermatomyositis 10 | 966
esophageal adenocarcinoma 10 | 737
gastric carcinoma 10 | 807
juvenile dermatomyositis 10 | 1,187
limb girdle muscular dystrophy 2A 10 | 213
Age related macular degeneration 9 | 72
Heart disease 9 | 306
Hemarthrosis 9 | 12
Liver Cirrhosis 9 | 181
Melanoma 9 | 711
Rheumatoid arthritis 9 | 1,191
mucosa-associated lymphoid tissue lymphoma 9 | 484
oligodendroglioma 9 | 2,850
Angioedema 8 | 38
Barrett's esophagus 8 | 182
Congenital afibrinogenemia 8 | 11
Ecchymosis 8 | 66
Hemophilia B 8 | 11
Hepatic veno-occlusive disease 8 | 16
Hypersensitivity reaction type II disease 8 | 253
Increased tendency to bruise 8 | 66
Menorrhagia 8 | 25
Peripheral vascular disease 8 | 87
Purpura 8 | 43
Skin cancer 8 | 469
Thromboembolism 8 | 15
astrocytic glioma 8 | 2,597
fibroadenoma 8 | 559
interstitial lung disease 8 | 298
nasopharyngeal carcinoma 8 | 1,058
primary Sjogren syndrome 8 | 735
Arthritis 7 | 290
Chemical and Drug Induced Liver Injury 7 | 195
Epistaxis 7 | 43
Factor VIII deficiency 7 | 10
Schizophrenia 7 | 1,160
Vasculitis 7 | 80
astrocytoma 7 | 1,146
cutaneous lupus erythematosus 7 | 1,057
periodontitis 7 | 293
primary pancreatic ductal adenocarcinoma 7 | 1,109
primitive neuroectodermal tumor 7 | 3,035

Tissue

Liver and Pancreas 59 | 16,750
Urinary Tract 59 | 16,678
Endocrine System 58 | 18,159
Digestive Tract 57 | 17,369
Male tissues 56 | 17,142
Skin and soft tissues 56 | 17,230
Female tissues 55 | 17,400
Blood and immune system 53 | 16,909
Nervous System 53 | 16,725
Respiratory system 53 | 16,393
Cardiovascular System 50 | 15,192

Target Family

Non-IDG 38 | 12,091
Enzyme 17 | 4,145
GPCR 4 | 408

WikiPathways Pathway

Complement and Coagulation Cas... 59 | 59
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Coagulation factor V F5 Tbio Non-IDG -2.73955 525.3 198
Complement C1q subcomponent subunit A C1QA Tbio Non-IDG -1.73823 51.2 241
Membrane cofactor protein CD46 Tbio Non-IDG -2.94025 875.6 770
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
Protein ERGIC-53 LMAN1 Tbio Non-IDG -2.44907 270.7 118
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453
Coagulation factor VIII F8 Tbio Non-IDG -3.59602 3983.5 652
Complement receptor type 2 CR2 Tbio Non-IDG -2.97911 940.3 934