Development Level

Tbio 17 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613

IMPC Phenotype

cardiovascular system phenotyp... 2 | 36
increased circulating sodium l... 2 | 71
abnormal behavior 1 | 298
abnormal placement of pupils 1 | 6
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
shortened RR interval 1 | 17

Disease

Carcinoma 16 | 11,493
Autosomal recessive predisposition 13 | 1,442
lung cancer 12 | 4,740
non-small cell lung cancer 12 | 2,890
ovarian cancer 12 | 8,520
lung carcinoma 11 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Complement deficiency 10 | 14
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
psoriasis 10 | 6,694
adrenocortical carcinoma 9 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
Meningitis 8 | 67
glioblastoma 8 | 5,792
lung adenocarcinoma 8 | 2,716
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
Immunologic Deficiency Syndromes 7 | 113
Liver Cirrhosis, Experimental 7 | 769
Systemic lupus erythematosus 7 | 194
acute quadriplegic myopathy 7 | 1,158
dermatomyositis 7 | 966
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
limb girdle muscular dystrophy 2A 7 | 213
malignant mesothelioma 7 | 3,232
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
Duchenne muscular dystrophy 6 | 601
Rheumatoid arthritis 6 | 1,191
Skin cancer 6 | 469
interstitial cystitis 6 | 2,312
juvenile dermatomyositis 6 | 1,187
pancreatic cancer 6 | 2,398
Becker muscular dystrophy 5 | 191
Complement deficiency disease 5 | 6
Kidney cancer 5 | 2,613
Lupus Erythematosus, Systemic 5 | 67
Melanoma 5 | 711
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
group 3 medulloblastoma 5 | 4,104
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
medulloblastoma, large-cell 5 | 6,241
primary Sjogren syndrome 5 | 735
Age related macular degeneration 4 | 72
Atopic dermatitis 4 | 952
Breast cancer 4 | 3,578
Down syndrome 4 | 499
Kidney disease 4 | 430
Lupus erythematosus 4 | 57
Macular degeneration 4 | 65
Recurrent infections 4 | 48
Type 1 diabetes mellitus 4 | 109
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
ependymoma 4 | 4,679
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
Anemia 3 | 365
Arthritis 3 | 290
Autoimmune Diseases 3 | 67
C1q DEFICIENCY 3 | 3
Decreased serum complement factor I 3 | 4
Endometriosis 3 | 540
Glomerulonephritis, IGA 3 | 34
Hemolytic-Uremic Syndrome 3 | 30
IGA Glomerulonephritis 3 | 50
Increased susceptibility to Neisseria meningitidis infections 3 | 4
Liver cancer 3 | 604
Neisseriaceae Infections 3 | 3
Schizophrenia 3 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic kidney disease 3 | 90
osteosarcoma 3 | 7,950
periodontitis 3 | 293
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
Cancer 2 | 2,499
Ehlers-Danlos syndrome 2 | 43
Gingival Hyperplasia 2 | 34
Gingival Hypertrophy 2 | 34
Gingival Overgrowth 2 | 36
Joint hyperflexibility 2 | 78
Multiple Sclerosis 2 | 540
Peritonitis 2 | 43
Pneumonia 2 | 174
Progressive relapsing multiple sclerosis 2 | 19
Relapsing fever 2 | 14
Skin hyperelastic 2 | 32
Vascular disease 2 | 319
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
fibroadenoma 2 | 559
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064

Tissue

Liver and Pancreas 22 | 16,750
Urinary Tract 22 | 16,678
Endocrine System 21 | 18,159
Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Female tissues 20 | 17,400
Male tissues 20 | 17,142
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Cardiovascular System 19 | 15,192
Nervous System 18 | 16,725

Target Family

Non-IDG 19 | 12,091
Enzyme 3 | 4,145

WikiPathways Pathway

Complement Activation 22 | 22
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement C1q subcomponent subunit A C1QA Tbio Non-IDG -1.73823 51.2 241
Mannan-binding lectin serine protease 2 MASP2 Tbio Enzyme -2.24966 184.0 195
Complement factor D CFD Tchem Enzyme -2.41491 244.6 226
Mannan-binding lectin serine protease 1 MASP1 Tbio Enzyme -2.49040 334.0 223
Complement C4-B C4B Tbio Non-IDG -2.99381 1011.9 185
Complement C4-A C4B Tbio Non-IDG -3.04538 1109.8 297
Complement C3 C3 Tbio Non-IDG -3.55963 3446.1 1079
Complement C5 C5 Tclin Non-IDG -2.26690 170.8 448
Complement component C6 C6 Tbio Non-IDG -1.55226 36.1 153
Complement component C9 C9 Tbio Non-IDG -1.88910 74.6 285