Development Level

Tbio 37 | 11,445
Tchem 10 | 1,598
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased body weight 2 | 161
abnormal anxiety-related respo... 1 | 1
abnormal behavioral response t... 1 | 66
abnormal retina morphology 1 | 71
abnormal social-conspecific in... 1 | 3
abnormal vertebrae morphology 1 | 18
decreased B cell number 1 | 5
decreased anxiety-related resp... 1 | 12
decreased mean corpuscular vol... 1 | 79
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased exploration in new e... 1 | 8
increased lean body mass 1 | 172
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
shortened RR interval 1 | 17

Disease

Carcinoma 33 | 11,493
Cancer 31 | 2,499
lung cancer 25 | 4,740
malignant mesothelioma 24 | 3,232
medulloblastoma, large-cell 24 | 6,241
psoriasis 23 | 6,694
ovarian cancer 22 | 8,520
glioblastoma 21 | 5,792
osteosarcoma 21 | 7,950
Breast cancer 18 | 3,578
cystic fibrosis 18 | 1,696
ependymoma 18 | 4,679
atypical teratoid / rhabdoid tumor 17 | 5,112
adult high grade glioma 15 | 3,801
Heart disease 14 | 306
group 3 medulloblastoma 14 | 4,104
lung carcinoma 14 | 2,843
non-small cell lung cancer 14 | 2,890
Astrocytoma, Pilocytic 13 | 3,081
Kidney cancer 13 | 2,613
diabetes mellitus 13 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung adenocarcinoma 12 | 2,716
Osteoporosis 11 | 363
astrocytic glioma 11 | 2,597
breast carcinoma 11 | 1,638
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
invasive ductal carcinoma 11 | 2,951
oligodendroglioma 11 | 2,850
ulcerative colitis 11 | 1,819
Cardiomyopathy 10 | 116
Congenital heart disease 10 | 93
Schizophrenia 10 | 1,160
pancreatic cancer 10 | 2,398
Alzheimer's disease 9 | 658
Autosomal recessive predisposition 9 | 1,442
Myocardial Infarction 9 | 151
colon cancer 9 | 1,478
ductal carcinoma in situ 9 | 1,745
pituitary cancer 9 | 1,972
primitive neuroectodermal tumor 9 | 3,035
Bipolar Disorder 8 | 666
Breast Neoplasms 8 | 445
Cognitive delay 8 | 608
Cryptorchidism 8 | 296
Global developmental delay 8 | 608
Hypertension 8 | 396
Mammary Neoplasms 8 | 425
Mental and motor retardation 8 | 608
Short stature 8 | 531
group 4 medulloblastoma 8 | 1,855
Arthritis 7 | 290
Cardiomegaly 7 | 116
Cerebrovascular disease 7 | 238
Cleft Palate 7 | 271
Diaphragmatic Hernia 7 | 40
Heart failure 7 | 162
Hernia, Diaphragmatic 7 | 40
Kidney disease 7 | 430
Liver Cirrhosis, Experimental 7 | 769
Muscle hypotonia 7 | 571
Neoplasm Invasiveness 7 | 161
gastric carcinoma 7 | 807
subependymal giant cell astrocytoma 7 | 2,287
Anemia 6 | 365
Brachydactyly 6 | 156
Cardiomyopathy, Dilated 6 | 83
Cell Transformation, Neoplastic 6 | 97
Colorectal Neoplasms 6 | 243
Coronary artery disease 6 | 268
Depressive disorder 6 | 409
Dilated cardiomyopathy 6 | 56
Duchenne muscular dystrophy 6 | 601
Exophthalmos 6 | 112
Fetal Growth Retardation 6 | 189
Hypertrophic Cardiomyopathy 6 | 117
Hypoplastic mandible condyle 6 | 275
Infant, Small for Gestational Age 6 | 176
Intrauterine retardation 6 | 176
Liver disease 6 | 237
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Neoplastic Cell Transformation 6 | 89
Prominent eyes 6 | 96
Prominent globes 6 | 96
Prostatic Neoplasms 6 | 495
Protruding eyes 6 | 96
Ventricular Septal Defects 6 | 119
facioscapulohumeral dystrophy 6 | 288
medulloblastoma 6 | 720
tuberculosis 6 | 2,010
Myocardial Ischemia 5 | 169
Rheumatoid arthritis 5 | 1,191
adrenocortical carcinoma 5 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
primary pancreatic ductal adenocarcinoma 5 | 1,109

Tissue

Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Digestive Tract 50 | 17,369
Skin and soft tissues 50 | 17,230
Male tissues 48 | 17,142
Blood and immune system 47 | 16,909
Liver and Pancreas 46 | 16,750
Respiratory system 46 | 16,393
Urinary Tract 46 | 16,678
Nervous System 44 | 16,725
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 21 | 12,091
Transcription Factor 21 | 1,400
Kinase 7 | 634
Enzyme 2 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

WikiPathways Pathway

Cardiac Progenitor Differentia... 53 | 53
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Vascular endothelial growth factor receptor 2 KDR Tclin Kinase -3.67555 4544.8 2373
Insulin INS Tbio Non-IDG -5.17849 146933.7 2197
Neural cell adhesion molecule 1 NCAM1 Tbio Non-IDG -3.58910 3930.7 1982
Troponin I, cardiac muscle TNNI3 Tbio Non-IDG -3.55281 3485.6 1706
Mitogen-activated protein kinase 14 MAPK14 Tchem Kinase -3.36007 2240.8 1574