Development Level

Tbio 31 | 11,178
Tchem 16 | 1,885
Tclin 6 | 612

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased body weight 2 | 161
abnormal anxiety-related respo... 1 | 1
abnormal behavioral response t... 1 | 66
abnormal retina morphology 1 | 71
abnormal social-conspecific in... 1 | 3
abnormal vertebrae morphology 1 | 18
decreased B cell number 1 | 5
decreased anxiety-related resp... 1 | 12
decreased mean corpuscular vol... 1 | 79
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased exploration in new e... 1 | 8
increased lean body mass 1 | 172
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
shortened RR interval 1 | 17

Disease

Carcinoma 28 | 11,192
Cancer 25 | 2,388
psoriasis 21 | 6,514
lung cancer 20 | 4,607
malignant mesothelioma 20 | 3,135
medulloblastoma, large-cell 19 | 6,086
osteosarcoma 18 | 7,766
ovarian cancer 18 | 8,297
glioblastoma 17 | 5,635
Breast cancer 16 | 3,469
ependymoma 15 | 4,559
Heart disease 14 | 288
cystic fibrosis 14 | 1,629
adult high grade glioma 13 | 3,701
atypical teratoid / rhabdoid tumor 12 | 4,971
diabetes mellitus 12 | 1,683
Astrocytoma, Pilocytic 11 | 3,006
Kidney cancer 11 | 2,548
lung adenocarcinoma 11 | 2,627
lung carcinoma 11 | 2,755
Cardiomyopathy 10 | 116
Osteoporosis 10 | 348
Schizophrenia 10 | 1,136
group 3 medulloblastoma 10 | 4,002
ulcerative colitis 10 | 1,765
Alzheimer's disease 9 | 640
Congenital heart disease 9 | 91
astrocytic glioma 9 | 2,530
breast carcinoma 9 | 1,589
interstitial cystitis 9 | 2,237
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,204
invasive ductal carcinoma 9 | 2,867
non-small cell lung cancer 9 | 2,799
oligodendroglioma 9 | 2,768
pancreatic cancer 9 | 2,322
Autosomal recessive predisposition 8 | 1,407
Bipolar Disorder 8 | 646
Breast Neoplasms 8 | 423
Hypertension 8 | 372
Mammary Neoplasms 8 | 403
Myocardial Infarction 8 | 142
group 4 medulloblastoma 8 | 1,806
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,902
pituitary cancer 8 | 1,915
Arthritis 7 | 276
Cardiomegaly 7 | 114
Cerebrovascular disease 7 | 223
Cognitive delay 7 | 596
Cryptorchidism 7 | 287
Diaphragmatic Hernia 7 | 40
Global developmental delay 7 | 596
Heart failure 7 | 157
Hernia, Diaphragmatic 7 | 40
Kidney disease 7 | 411
Liver Cirrhosis, Experimental 7 | 733
Mental and motor retardation 7 | 596
Short stature 7 | 514
colon cancer 7 | 1,428
ductal carcinoma in situ 7 | 1,686
gastric carcinoma 7 | 781
primitive neuroectodermal tumor 7 | 2,957
Brachydactyly 6 | 154
Cardiomyopathy, Dilated 6 | 83
Cleft Palate 6 | 265
Coronary artery disease 6 | 253
Depressive disorder 6 | 401
Dilated cardiomyopathy 6 | 56
Duchenne muscular dystrophy 6 | 587
Exophthalmos 6 | 110
Fetal Growth Retardation 6 | 186
Hypertrophic Cardiomyopathy 6 | 115
Hypoplastic mandible condyle 6 | 273
Infant, Small for Gestational Age 6 | 174
Intrauterine retardation 6 | 174
Liver disease 6 | 227
Mandibular hypoplasia 6 | 273
Micrognathism 6 | 273
Neoplasm Invasiveness 6 | 151
Prominent eyes 6 | 95
Prominent globes 6 | 95
Protruding eyes 6 | 95
facioscapulohumeral dystrophy 6 | 281
medulloblastoma 6 | 702
subependymal giant cell astrocytoma 6 | 2,230
tuberculosis 6 | 1,963
Anemia 5 | 353
Atherosclerosis 5 | 276
Bilateral fifth finger clinodactyly 5 | 109
Curvature of little finger 5 | 109
Lung disease 5 | 135
Myocardial Ischemia 5 | 162
Myopathy 5 | 185
Polycystic ovary syndrome 5 | 348
Prostatic Neoplasms 5 | 472
Rheumatoid arthritis 5 | 1,156
Ventricular Septal Defects 5 | 113
adrenocortical carcinoma 5 | 1,385
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 492
cutaneous lupus erythematosus 5 | 1,016

Tissue

Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Digestive Tract 50 | 17,369
Skin and soft tissues 50 | 17,230
Male tissues 48 | 17,142
Blood and immune system 47 | 16,909
Liver and Pancreas 46 | 16,750
Respiratory system 46 | 16,393
Urinary Tract 46 | 16,678
Nervous System 44 | 16,725
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 21 | 12,091
Transcription Factor 21 | 1,400
Kinase 7 | 634
Enzyme 2 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

WikiPathways Pathway

Cardiac Progenitor Differentia... 53 | 53
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein lin-28 homolog A LIN28A Tbio Transcription Factor -2.44709 277.0 494
Homeobox protein NANOG NANOG Tchem Transcription Factor -2.94914 1130.5 958
Transcription factor SOX-1 SOX1 Tbio Transcription Factor -2.05328 109.0 220
Zinc finger protein 42 homolog ZFP42 Tbio Transcription Factor -1.19303 18.8 257
Hepatocyte nuclear factor 3-beta FOXA2 Tbio Transcription Factor -2.42896 256.9 658
Iroquois-class homeodomain protein IRX-4 IRX4 Tbio Transcription Factor -1.21939 16.8 36
Transcription factor GATA-4 GATA4 Tbio Transcription Factor -2.90202 763.9 496
Mesoderm posterior protein 1 MESP1 Tbio Transcription Factor -1.38536 26.8 208
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570