Development Level

Tbio 9 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
decreased startle reflex 1 | 75
trunk curl 1 | 16

Disease

Carcinoma 9 | 11,493
ovarian cancer 9 | 8,520
osteosarcoma 8 | 7,950
group 4 medulloblastoma 6 | 1,855
invasive ductal carcinoma 6 | 2,951
Brachydactyly 5 | 156
Cancer 5 | 2,499
Short stature 5 | 531
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
psoriasis 5 | 6,694
Craniofacial Abnormalities 4 | 151
Fibrodysplasia ossificans progressiva 4 | 17
Pick disease 4 | 1,894
Simple syndactyly of toes, first web space 4 | 23
acute myeloid leukemia 4 | 783
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
Ankylosis 3 | 28
Aplasia/Hypoplasia of the middle phalanges of the toes 3 | 5
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Broad hallux 3 | 29
Cleft Palate 3 | 271
Craniosynostosis 3 | 74
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Hereditary hemorrhagic telangiectasia 3 | 13
Hypoplasia of the maxilla 3 | 66
Hypoplastic feet 3 | 66
Hypoplastic finger 3 | 17
Hypotrophic malar bone 3 | 129
Hypotrophic maxilla 3 | 66
Malar flattening 3 | 129
Maxillary retrognathia 3 | 66
Orbital separation excessive 3 | 244
Osteoporosis 3 | 363
Radially deviated fingers 3 | 38
Retrusion of upper jaw bones 3 | 66
Rheumatoid arthritis 3 | 1,191
Short finger 3 | 17
Short hallux 3 | 16
Short middle phalanx of the 5th finger 3 | 13
Short philtrum 3 | 53
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
cystic fibrosis 3 | 1,696
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Abdominal Pain 2 | 98
Abnormal skeletal development 2 | 60
Adenoma 2 | 167
Anemia 2 | 365
Breast Neoplasms 2 | 445
Carpal synostosis 2 | 12
Class III malocclusion 2 | 78
Congenital deafness 2 | 185
Curvature of little finger 2 | 110
Deafness 2 | 198
Decreased projection of midface 2 | 105
Eye Abnormalities 2 | 35
Familial adenomatous polyposis 2 | 32
Hearing Loss, Partial 2 | 185
Hemoglobin low 2 | 124
Hyperopia 2 | 70
Hypertrophy of lower jaw 2 | 78
Hypoalbuminemia 2 | 24
Hypoplastic toes 2 | 29
Hypotrophic midface 2 | 105
Increased size of mandible 2 | 78
Juvenile polyposis syndrome 2 | 7
Mammary Neoplasms 2 | 425
Mandibular hyperplasia 2 | 78
Microstomia 2 | 78
Midface retrusion 2 | 105
Multiple synostoses syndrome 2 | 9
Osteoarthritis 2 | 184
Osteochondrodysplasias 2 | 72
Osteonecrosis 2 | 27
Primary pulmonary hypertension 2 | 14
Small midface 2 | 105
Stomach Neoplasms 2 | 300
Telangiectasis 2 | 36
Thin upper lip vermilion 2 | 67
X-linked cerebral adrenoleukodystrophy 2 | 116
active Crohn's disease 2 | 922
hearing impairment 2 | 199
mandibular excess (physical finding) 2 | 78
posterior fossa group A ependymoma 2 | 468
sarcoidosis 2 | 370

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 4 | 12,091
Transcription Factor 4 | 1,400
Kinase 3 | 634
Enzyme 1 | 4,145

WikiPathways Pathway

Bone Morphogenic Protein (BMP)... 12 | 12
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -2.00303 86.8 498
Protein Tob2 TOB2 Tbio Non-IDG -1.58444 34.4 108
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
E3 ubiquitin-protein ligase SMURF1 SMURF1 Tbio Enzyme -1.95365 89.3 331
Protein Tob1 TOB1 Tbio Non-IDG -1.63807 44.1 190