Development Level

Tclin 7 | 613
Tbio 5 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

increased circulating sodium l... 2 | 71
abnormal behavior 1 | 298
abnormal locomotor behavior 1 | 24
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased pulmonary respirator... 1 | 5
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
thin ventricular wall 1 | 24

Disease

Carcinoma 11 | 11,493
Bipolar Disorder 10 | 666
Depressive disorder 10 | 409
Schizophrenia 10 | 1,160
Mental Depression 9 | 333
Major Depressive Disorder 8 | 301
Parkinson's disease 8 | 392
Alcoholic Intoxication, Chronic 7 | 289
Mood Disorders 7 | 184
Unipolar Depression 7 | 250
psoriasis 7 | 6,694
Attention deficit hyperactivity disorder 6 | 278
Autosomal recessive predisposition 6 | 1,442
Seizures 6 | 596
lung cancer 6 | 4,740
Autistic Disorder 5 | 364
Blepharoptosis 5 | 231
Hypertension 5 | 396
Pheochromocytoma 5 | 24
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
lung carcinoma 5 | 2,843
medulloblastoma, large-cell 5 | 6,241
Alzheimer's disease 4 | 658
Astrocytoma, Pilocytic 4 | 3,081
Brain disease 4 | 96
Cognitive delay 4 | 608
Constipation 4 | 181
Dementia 4 | 175
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Mental and motor retardation 4 | 608
Toxic encephalopathy 4 | 141
aldosterone-producing adenoma 4 | 665
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
pituitary cancer 4 | 1,972
Alcohol dependence 3 | 107
Cocaine Dependence 3 | 51
Cocaine-Related Disorders 3 | 92
Depression, Bipolar 3 | 12
Epilepsy 3 | 792
Hyperprolactinemia 3 | 27
Hyperreflexia 3 | 209
Infantile onset 3 | 238
Mental disorders 3 | 12
Neuroblastoma 3 | 80
Personality disorder 3 | 25
Psychotic Disorders 3 | 151
Sudden infant death syndrome 3 | 32
Tremor 3 | 113
adrenocortical carcinoma 3 | 1,428
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
nephrosclerosis 3 | 333
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
Amphetamine-Related Disorders 2 | 74
Axial hypotonia 2 | 46
Babinski Reflex 2 | 100
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Cognition Disorders 2 | 32
Diarrhea 2 | 253
Down syndrome 2 | 499
Dyschezia 2 | 135
Dyskinesia, Drug-Induced 2 | 15
Dystonia 2 | 164
Gilles de la Tourette syndrome 2 | 47
Heroin dependence 2 | 30
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Mammary Neoplasms 2 | 425
Multiple system atrophy 2 | 29
Nerve Degeneration 2 | 121
Neuropathy 2 | 261
Panic disorder 2 | 61
Parkinson Disease 2 | 64
Parkinsonian Disorders 2 | 56
Prostatic Neoplasms 2 | 495
Ptosis 2 | 48
Succinic semialdehyde dehydrogenase deficiency 2 | 16
adrenocortical adenoma 2 | 131
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
facioscapulohumeral dystrophy 2 | 288
invasive ductal carcinoma 2 | 2,951
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
obsessive-compulsive disorder 2 | 61
oligodendroglioma 2 | 2,850
ulcerative colitis 2 | 1,819

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Skin and soft tissues 15 | 17,230
Female tissues 14 | 17,400
Blood and immune system 13 | 16,909
Urinary Tract 12 | 16,678
Respiratory system 11 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Enzyme 15 | 4,145

WikiPathways Pathway

Biogenic Amine Synthesis 15 | 15
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
Phenylethanolamine N-methyltransferase PNMT Tchem Enzyme -2.90323 857.6 277
Phenylalanine-4-hydroxylase PAH Tclin Enzyme -2.84378 662.6 193
Acetylcholinesterase ACHE Tclin Enzyme -3.49768 2470.5 505
Histidine decarboxylase HDC Tbio Enzyme -2.65393 472.2 175
Acetylserotonin O-methyltransferase ASMT Tbio Enzyme -2.40166 255.0 111
Catechol O-methyltransferase COMT Tclin Enzyme -3.46304 2976.1 433
Aromatic-L-amino-acid decarboxylase DDC Tclin Enzyme -2.78263 593.3 412
Serotonin N-acetyltransferase AANAT Tbio Enzyme -2.28389 189.1 196
Tryptophan 5-hydroxylase 1 TPH1 Tclin Enzyme -2.93036 772.3 415