Development Level

Tchem 4 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

decreased body weight 1 | 161
decreased circulating triglyce... 1 | 79
hyperactivity 1 | 148
increased IgA level 1 | 1
increased startle reflex 1 | 112
thrombocytopenia 1 | 56

Disease

Cancer 6 | 2,499
Prostatic Neoplasms 6 | 495
Alcoholic Intoxication, Chronic 4 | 289
Carcinoma, Hepatocellular 4 | 228
Liver carcinoma 4 | 240
Lung Neoplasms 4 | 232
Asthma 3 | 385
Bladder Neoplasm 3 | 112
Carcinoma 3 | 11,493
Chemical and Drug Induced Liver Injury 3 | 195
Micronuclei, Chromosome-Defective 3 | 25
Parkinson Disease 3 | 64
Schizophrenia 3 | 1,160
Urinary Bladder Neoplasms 3 | 114
Xeroderma pigmentosum group D 3 | 33
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
Acute kidney injury 2 | 70
Alcohol withdrawal syndrome 2 | 20
Amphetamine-Related Disorders 2 | 74
Atherosclerosis 2 | 291
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Carcinoma, Non-Small-Cell Lung 2 | 107
Chronic obstructive pulmonary disease 2 | 184
Colorectal Neoplasms 2 | 243
Diabetes Mellitus, Experimental 2 | 108
Drug Eruptions 2 | 18
Endometriosis 2 | 540
Kidney Diseases 2 | 114
Liver Cirrhosis, Alcoholic 2 | 16
Liver neoplasms 2 | 130
Lymphoma, Non-Hodgkin 2 | 24
Mesothelioma, Malignant 2 | 105
Multiple myeloma 2 | 1,332
Non-alcoholic Fatty Liver Disease 2 | 42
Obesity 2 | 678
Occupational Diseases 2 | 12
Precursor Cell Lymphoblastic Leukemia Lymphoma 2 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 2 | 49
Rheumatoid arthritis 2 | 1,191
Urticaria 2 | 67
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung carcinoma 2 | 317
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
Adenocarcinoma 1 | 122
Adverse reaction to drug 1 | 61
Alcohol dependence 1 | 107
Animal Mammary Neoplasms 1 | 136
Arthritis, Experimental 1 | 39
Bipolar I disorder 1 | 23
Brain Diseases 1 | 24
Brain Edema 1 | 50
Brain Injuries 1 | 65
Breast Neoplasms 1 | 445
Bronchitis 1 | 43
Carcinoma, Renal Cell 1 | 124
Carcinoma, Squamous Cell 1 | 110
Cardiomegaly 1 | 116
Common cold 1 | 67
Dermatologic disorders 1 | 93
Drug allergy 1 | 36
Drug-Related Side Effects and Adverse Reactions 1 | 62
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Liver disease 1 | 237
Lung diseases 1 | 50
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mastitis 1 | 48
Necrosis 1 | 53
Neurodegenerative Disorders 1 | 79
Neutropenia 1 | 72
Pancreatitis 1 | 123
Periodontal disease 1 | 40
Pre-Eclampsia 1 | 68
Pruritus 1 | 58
Pulmonary emphysema 1 | 48
Purpura 1 | 43
Renal Cell Carcinoma 1 | 214
Rickets 1 | 49
Skin Diseases 1 | 71
Skin disease 1 | 66
Squamous cell carcinoma 1 | 129
Wounds and Injuries 1 | 18
sarcoidosis 1 | 370

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192

Target Family

Enzyme 5 | 4,145
Non-IDG 1 | 12,091

WikiPathways Pathway

Benzene metabolism 6 | 6
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase DHDH Tbio Enzyme -2.59951 390.9 103
NAD(P)H dehydrogenase [quinone] 1 NQO1 Tchem Enzyme -3.12097 1326.4 550
Glutathione S-transferase Mu 1 GSTM1 Tbio Enzyme -3.27893 1991.1 469
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Epoxide hydrolase 1 EPHX1 Tchem Enzyme -2.76490 601.9 276
Cytochrome P450 2E1 CYP2E1 Tchem Non-IDG -3.41434 2667.8 411