Development Level

Tchem 20 | 1,598
Tbio 17 | 11,445
Tclin 9 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal heart morphology 2 | 162
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

ovarian cancer 35 | 8,520
Carcinoma 34 | 11,493
Cancer 33 | 2,499
psoriasis 29 | 6,694
osteosarcoma 27 | 7,950
glioblastoma 26 | 5,792
lung cancer 26 | 4,740
Breast cancer 23 | 3,578
medulloblastoma, large-cell 20 | 6,241
Breast Neoplasms 19 | 445
Mammary Neoplasms 19 | 425
atypical teratoid / rhabdoid tumor 17 | 5,112
malignant mesothelioma 17 | 3,232
diabetes mellitus 16 | 1,728
Schizophrenia 15 | 1,160
Stomach Neoplasms 15 | 300
oligodendroglioma 15 | 2,850
Adenoma 14 | 167
Lung Neoplasms 14 | 232
Prostatic Neoplasms 14 | 495
Kidney cancer 13 | 2,613
Liver Cirrhosis, Experimental 13 | 769
Melanoma 13 | 711
ependymoma 13 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
juvenile dermatomyositis 13 | 1,187
tuberculosis 13 | 2,010
Bladder Neoplasm 12 | 112
Carcinoma, Hepatocellular 12 | 228
Colorectal Neoplasms 12 | 243
Hypertensive disease 12 | 292
Liver carcinoma 12 | 240
Obesity 12 | 678
Rheumatoid arthritis 12 | 1,191
Urinary Bladder Neoplasms 12 | 114
acute quadriplegic myopathy 12 | 1,158
astrocytic glioma 12 | 2,597
lung adenocarcinoma 12 | 2,716
Carcinoma, Squamous Cell 11 | 110
Colonic Neoplasms 11 | 142
Endometriosis 11 | 540
Neoplasm Metastasis 11 | 168
Squamous cell carcinoma 11 | 129
Vascular disease 11 | 319
adrenocortical carcinoma 11 | 1,428
group 3 medulloblastoma 11 | 4,104
Dull intelligence 10 | 645
Intellectual disability 10 | 1,016
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Neoplasms, Experimental 10 | 40
Poor school performance 10 | 645
adult high grade glioma 10 | 3,801
astrocytoma 10 | 1,146
breast carcinoma 10 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
lung carcinoma 10 | 2,843
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
primitive neuroectodermal tumor 10 | 3,035
subependymal giant cell astrocytoma 10 | 2,287
Carcinoma, Non-Small-Cell Lung 9 | 107
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Hypertension 9 | 396
Liver neoplasms 9 | 130
Mental and motor retardation 9 | 608
Multiple myeloma 9 | 1,332
Short stature 9 | 531
cystic fibrosis 9 | 1,696
dermatomyositis 9 | 966
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
non-small cell lung carcinoma 9 | 317
pituitary cancer 9 | 1,972
Adenocarcinoma 8 | 122
Adenocarcinoma of lung 8 | 142
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
Bipolar Disorder 8 | 666
Blepharoptosis 8 | 231
Congenital Epicanthus 8 | 177
Diarrhea 8 | 253
Downward slant of palpebral fissure 8 | 158
Heart disease 8 | 306
Hyperglycemia 8 | 137
Low set ears 8 | 181
Mood Disorders 8 | 184
Muscle hypotonia 8 | 571
Neoplasm Invasiveness 8 | 161
Orbital separation excessive 8 | 244
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
ulcerative colitis 8 | 1,819
Immune system cancer 7 | 140
Pick disease 7 | 1,894
aldosterone-producing adenoma 7 | 665
interstitial cystitis 7 | 2,312

Tissue

Endocrine System 46 | 18,159
Liver and Pancreas 46 | 16,750
Blood and immune system 45 | 16,909
Digestive Tract 45 | 17,369
Female tissues 45 | 17,400
Male tissues 45 | 17,142
Nervous System 45 | 16,725
Respiratory system 45 | 16,393
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 16 | 12,091
Transcription Factor 11 | 1,400
Enzyme 10 | 4,145
Kinase 7 | 634
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

WikiPathways Pathway

Aryl Hydrocarbon Receptor 46 | 46
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aryl hydrocarbon receptor repressor AHRR Tbio Transcription Factor -1.68768 52.8 77
Krueppel-like factor 6 KLF6 Tbio Transcription Factor -2.37304 253.6 161
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
NAD(P)H dehydrogenase [quinone] 1 NQO1 Tchem Enzyme -3.12097 1326.4 550
Zinc finger protein PLAGL1 PLAGL1 Tbio Transcription Factor -2.07360 117.1 148
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150
Aryl hydrocarbon receptor AHR Tchem Transcription Factor 0.00000 773