Development Level

Tbio 54 | 11,651
Tchem 36 | 1,388
Tclin 2 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased mean corpuscular vol... 3 | 79
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
abnormal testis morphology 2 | 43
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased vertical activity 2 | 208
hyperactivity 2 | 148
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
small testis 2 | 58
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
absent testes 1 | 6
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
increased basophil cell number 1 | 7
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Cancer 73 | 2,499
ovarian cancer 56 | 8,520
lung cancer 53 | 4,740
psoriasis 48 | 6,694
Carcinoma 44 | 11,493
glioblastoma 43 | 5,792
osteosarcoma 43 | 7,950
medulloblastoma, large-cell 35 | 6,241
atypical teratoid / rhabdoid tumor 29 | 5,112
malignant mesothelioma 29 | 3,232
pancreatic cancer 29 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
lung carcinoma 26 | 2,843
Astrocytoma, Pilocytic 25 | 3,081
adult high grade glioma 25 | 3,801
ependymoma 25 | 4,679
group 3 medulloblastoma 24 | 4,104
non-small cell lung cancer 23 | 2,890
diabetes mellitus 22 | 1,728
tuberculosis 22 | 2,010
subependymal giant cell astrocytoma 21 | 2,287
Rheumatoid arthritis 20 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
lung adenocarcinoma 20 | 2,716
Breast cancer 19 | 3,578
ulcerative colitis 19 | 1,819
Vascular disease 18 | 319
oligodendroglioma 18 | 2,850
primitive neuroectodermal tumor 18 | 3,035
adrenocortical carcinoma 17 | 1,428
cutaneous lupus erythematosus 17 | 1,057
Arthritis 16 | 290
Schizophrenia 16 | 1,160
invasive ductal carcinoma 16 | 2,951
colon cancer 15 | 1,478
pituitary cancer 15 | 1,972
group 4 medulloblastoma 14 | 1,855
interstitial cystitis 14 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Alzheimer's disease 13 | 658
Breast Neoplasms 13 | 445
Kidney disease 13 | 430
Mammary Neoplasms 13 | 425
Pick disease 13 | 1,894
Prostatic Neoplasms 13 | 495
breast carcinoma 13 | 1,638
Brain Ischemia 12 | 110
Hypersensitivity reaction type II disease 12 | 253
Lung Neoplasms 12 | 232
Stomach Neoplasms 12 | 300
astrocytoma 12 | 1,146
hepatocellular carcinoma 12 | 547
juvenile dermatomyositis 12 | 1,187
primary pancreatic ductal adenocarcinoma 12 | 1,109
Inflammatory bowel disease 11 | 151
Obesity 11 | 678
active ulcerative colitis 11 | 764
acute quadriplegic myopathy 11 | 1,158
astrocytic glioma 11 | 2,597
Carcinoma, Hepatocellular 10 | 228
Liver carcinoma 10 | 240
Melanoma 10 | 711
Multiple myeloma 10 | 1,332
Renal Cell Carcinoma 10 | 214
Splenomegaly 10 | 190
Toxic encephalopathy 10 | 141
active Crohn's disease 10 | 922
acute myeloid leukemia 10 | 783
aldosterone-producing adenoma 10 | 665
cystic fibrosis 10 | 1,696
ductal carcinoma in situ 10 | 1,745
Asthma 9 | 385
Colonic Neoplasms 9 | 142
Diabetes Mellitus, Experimental 9 | 108
Diabetes Mellitus, Non-Insulin-Dependent 9 | 145
Diabetes Mellitus, Type 2 9 | 142
Esophageal Neoplasms 9 | 69
Eye disease 9 | 62
gastric carcinoma 9 | 807
pancreatic carcinoma 9 | 562
pediatric high grade glioma 9 | 1,064
Adenocarcinoma 8 | 122
Autosomal recessive predisposition 8 | 1,442
Carcinoma, Renal Cell 8 | 124
Kidney cancer 8 | 2,613
Liver Cirrhosis, Experimental 8 | 769
Liver disease 8 | 237
Lung disease 8 | 142
Lymphoma 8 | 81
Multiple Sclerosis 8 | 540
Myocardial Reperfusion Injury 8 | 37
Pancreatic Neoplasm 8 | 85
Pancreatic Neoplasms 8 | 85
Parkinson's disease 8 | 392
Pneumonia 8 | 174
primary Sjogren syndrome 8 | 735
spina bifida 8 | 1,074
Chronic Lymphocytic Leukemia 7 | 262
gastric cancer 7 | 459

Tissue

Blood and immune system 90 | 16,909
Digestive Tract 90 | 17,369
Female tissues 90 | 17,400
Nervous System 90 | 16,725
Skin and soft tissues 90 | 17,230
Endocrine System 89 | 18,159
Liver and Pancreas 89 | 16,750
Male tissues 89 | 17,142
Respiratory system 89 | 16,393
Urinary Tract 89 | 16,678
Cardiovascular System 87 | 15,192

Target Family

Non-IDG 62 | 12,091
Enzyme 17 | 4,145
Kinase 9 | 634
Transcription Factor 4 | 1,400

WikiPathways Pathway

Apoptosis Modulation and Signa... 92 | 92
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Apoptosis-inducing factor 2 AIFM2 Tbio Non-IDG -1.22943 14.9 217
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949
DNA fragmentation factor subunit beta DFFB Tbio Non-IDG -1.82600 60.8 383
Interleukin-1 receptor type 1 IL1R1 Tclin Non-IDG -2.68139 387.6 620