Development Level

Tbio 20 | 11,445
Tchem 14 | 1,598
Tclin 4 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating triglyce... 1 | 79
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
hyperactivity 1 | 148
increased basophil cell number 1 | 7
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

ovarian cancer 23 | 8,520
Carcinoma 22 | 11,493
glioblastoma 22 | 5,792
Cancer 21 | 2,499
medulloblastoma, large-cell 19 | 6,241
psoriasis 19 | 6,694
Alzheimer's disease 16 | 658
atypical teratoid / rhabdoid tumor 16 | 5,112
lung cancer 16 | 4,740
osteosarcoma 16 | 7,950
adult high grade glioma 15 | 3,801
ependymoma 15 | 4,679
Schizophrenia 14 | 1,160
Toxic encephalopathy 14 | 141
Depressive disorder 13 | 409
malignant mesothelioma 13 | 3,232
Astrocytoma, Pilocytic 12 | 3,081
Vascular disease 12 | 319
diabetes mellitus 12 | 1,728
Amyotrophic lateral sclerosis 11 | 451
Diabetes Mellitus, Experimental 11 | 108
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
oligodendroglioma 11 | 2,850
Brain Ischemia 10 | 110
Bipolar Disorder 9 | 666
Hypertension 9 | 396
Mental Depression 9 | 333
Multiple myeloma 9 | 1,332
Nerve Degeneration 9 | 121
Pick disease 9 | 1,894
adrenocortical carcinoma 9 | 1,428
group 4 medulloblastoma 9 | 1,855
lung carcinoma 9 | 2,843
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
Diabetes Mellitus, Non-Insulin-Dependent 8 | 145
Diabetes Mellitus, Type 2 8 | 142
Kidney disease 8 | 430
Myocardial Infarction 8 | 151
Neurodegenerative disease 8 | 414
Parkinson's disease 8 | 392
colon cancer 8 | 1,478
pancreatic cancer 8 | 2,398
subependymal giant cell astrocytoma 8 | 2,287
AMYOTROPHIC LATERAL SCLEROSIS 1 7 | 49
Obesity 7 | 678
Rheumatoid arthritis 7 | 1,191
astrocytic glioma 7 | 2,597
Breast Neoplasms 6 | 445
Edema 6 | 81
Hypertensive disease 6 | 292
Kidney cancer 6 | 2,613
Liver disease 6 | 237
Major Depressive Disorder 6 | 301
Mammary Neoplasms 6 | 425
Melanoma 6 | 711
Myocardial Reperfusion Injury 6 | 37
Prostatic Neoplasms 6 | 495
Reperfusion Injury 6 | 86
non-small cell lung cancer 6 | 2,890
pituitary cancer 6 | 1,972
Alzheimer Disease 5 | 83
Asthma 5 | 385
Atherosclerosis 5 | 291
Autosomal recessive predisposition 5 | 1,442
Brain disease 5 | 96
Breast cancer 5 | 3,578
Carcinoma, Hepatocellular 5 | 228
Cell Transformation, Neoplastic 5 | 97
Cerebral Hemorrhage 5 | 42
Cerebrovascular disease 5 | 238
Chemical and Drug Induced Liver Injury 5 | 195
Chronic Lymphocytic Leukemia 5 | 262
Colonic Neoplasms 5 | 142
Heart disease 5 | 306
Heart failure 5 | 162
Hepatitis, Chronic 5 | 23
Liver carcinoma 5 | 240
Lung Neoplasms 5 | 232
Lung disease 5 | 142
Multiple Sclerosis 5 | 540
Neoplastic Cell Transformation 5 | 89
Nervous System Diseases 5 | 53
Parkinson Disease 5 | 64
Status Epilepticus 5 | 98
Stomach Neoplasms 5 | 300
Unipolar Depression 5 | 250
Waldenstrons macroglobulinemia 5 | 765
aldosterone-producing adenoma 5 | 665
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
nervous system disorder 5 | 53
Arthritis 4 | 290
Down syndrome 4 | 499
Endometriosis 4 | 540
astrocytoma 4 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962

Tissue

Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Skin and soft tissues 37 | 17,230
Blood and immune system 36 | 16,909
Liver and Pancreas 36 | 16,750
Respiratory system 36 | 16,393
Urinary Tract 36 | 16,678
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 15 | 4,145
Kinase 4 | 634
Ion Channel 1 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

WikiPathways Pathway

Amyotrophic lateral sclerosis ... 38 | 38
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Derlin-1 DERL1 Tbio Non-IDG -1.88253 69.7 178
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Copper chaperone for superoxide dismutase CCS Tbio Enzyme -1.76183 50.7 209
Glutathione peroxidase 1 GPX1 Tbio Enzyme -2.94289 886.7 350
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
Mitochondrial import receptor subunit TOM40 homolog TOMM40 Tbio Non-IDG -2.21973 158.9 94
Excitatory amino acid transporter 2 SLC1A2 Tchem Transporter -2.96237 939.6 187
Nitric oxide synthase, brain NOS1 Tchem Enzyme -3.27741 1885.8 661