Development Level

Tbio 134 | 11,445
Tchem 20 | 1,598
Tclin 14 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
abnormal heart morphology 2 | 162
decreased heart weight 2 | 27
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
hypoactivity 2 | 132
increased circulating sodium l... 2 | 71
increased lymphocyte cell numb... 2 | 32
increased neutrophil cell numb... 2 | 46
abnormal behavior 1 | 298
abnormal colon morphology 1 | 3
abnormal cranium morphology 1 | 36
abnormal duodenum morphology 1 | 4
abnormal ear morphology 1 | 9
abnormal eye anterior chamber ... 1 | 9
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
decreased T cell number 1 | 15
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
enlarged testis 1 | 6
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased erythrocyte cell num... 1 | 39
increased granulocyte number 1 | 1
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Cancer 120 | 2,499
psoriasis 102 | 6,694
diabetes mellitus 96 | 1,728
Hypersensitivity reaction type II disease 95 | 253
Rheumatoid arthritis 84 | 1,191
Arthritis 79 | 290
Ankylosing spondylitis 76 | 140
Carcinoma 76 | 11,493
Behcet's disease 71 | 89
Juvenile rheumatoid arthritis 68 | 111
Uveitis 67 | 103
Acquired immunodeficiency syndrome 65 | 197
Human immunodeficiency virus infectious disease 62 | 138
Herpes zoster 60 | 68
Multiple Sclerosis 59 | 540
tuberculosis 59 | 2,010
Psoriatic arthritis 58 | 86
Dermatitis 55 | 157
Stevens-Johnson syndrome 53 | 92
dermatomyositis 51 | 966
lung cancer 44 | 4,740
lung carcinoma 44 | 2,843
ovarian cancer 44 | 8,520
Synovitis 41 | 78
Kidney disease 40 | 430
Hepatitis B 39 | 108
Behcet's syndrome 38 | 50
Takayasu's arteritis 38 | 53
glioblastoma 38 | 5,792
Anemia 37 | 365
Congenital adrenal hyperplasia 37 | 73
Liver disease 37 | 237
Nephritis 36 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
Primary immunodeficiency disease 34 | 54
Leprosy 33 | 73
interstitial cystitis 33 | 2,312
ulcerative colitis 32 | 1,819
non-small cell lung cancer 31 | 2,890
osteosarcoma 31 | 7,950
Astrocytoma, Pilocytic 30 | 3,081
invasive ductal carcinoma 30 | 2,951
Schizophrenia 29 | 1,160
sarcoidosis 29 | 370
malignant mesothelioma 28 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
Asthma 26 | 385
Systemic lupus erythematosus 26 | 194
cutaneous lupus erythematosus 26 | 1,057
Inflammatory bowel disease 25 | 151
lung adenocarcinoma 25 | 2,716
Skin disease 24 | 66
subependymal giant cell astrocytoma 24 | 2,287
Hemochromatosis 23 | 54
adult high grade glioma 23 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
Birdshot chorioretinopathy 21 | 23
breast carcinoma 21 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
medulloblastoma, large-cell 20 | 6,241
primary Sjogren syndrome 20 | 735
Berylliosis 19 | 28
Liver Cirrhosis, Experimental 19 | 769
Lung disease 19 | 142
Vasculitis 19 | 80
juvenile dermatomyositis 19 | 1,187
Arthritis, Rheumatoid 18 | 174
ependymoma 18 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
pancreatic cancer 18 | 2,398
Autosomal recessive predisposition 17 | 1,442
Breast cancer 17 | 3,578
Human immunodeficiency virus type 1, susceptibility to 17 | 26
Meningitis 17 | 67
Narcolepsy 17 | 72
Allergic hypersensitivity disease 16 | 126
Influenza 16 | 142
adrenocortical carcinoma 16 | 1,428
atypical teratoid / rhabdoid tumor 16 | 5,112
cystic fibrosis 16 | 1,696
head and neck cancer and chronic obstructive pulmonary disease 16 | 239
Atherosclerosis 15 | 291
Bipolar Disorder 15 | 666
Duchenne muscular dystrophy 15 | 601
Hypersensitivity 15 | 63
Pre-Eclampsia 15 | 68
Type 1 diabetes mellitus 15 | 109
active Crohn's disease 15 | 922
active ulcerative colitis 15 | 764
Chemical and Drug Induced Liver Injury 14 | 195
Fever 14 | 138
Hypereosinophilic syndrome 14 | 71
Immunologic Deficiency Syndromes 14 | 113
Malaria 14 | 160
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
colon cancer 14 | 1,478
ductal carcinoma in situ 14 | 1,745

Tissue

Liver and Pancreas 84 | 16,750
Blood and immune system 83 | 16,909
Digestive Tract 83 | 17,369
Urinary Tract 83 | 16,678
Endocrine System 82 | 18,159
Skin and soft tissues 82 | 17,230
Male tissues 81 | 17,142
Respiratory system 81 | 16,393
Female tissues 79 | 17,400
Nervous System 72 | 16,725
Cardiovascular System 71 | 15,192

Target Family

Non-IDG 150 | 12,091
Enzyme 8 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
Transporter 1 | 473

WikiPathways Pathway

Allograft Rejection 168 | 168
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
HLA class I histocompatibility antigen, A-80 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0