Development Level

Tbio 4 | 10,625
Tchem 4 | 1,890
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 5 | 633
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 2 | 187
abnormal behavioral response t... 1 | 52
abnormal blood vessel morpholo... 1 | 2
abnormal bone structure 1 | 131
cardiovascular system phenotyp... 1 | 35
decreased circulating glucose ... 1 | 121
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased mean corpuscular vol... 1 | 91

Disease

ovarian cancer 6 | 8,484
Cancer 4 | 2,346
malignant mesothelioma 4 | 3,162
osteosarcoma 4 | 7,933
Ataxia telangiectasia 3 | 31
Seckel syndrome 3 | 34
colon cancer 3 | 1,475
group 3 medulloblastoma 3 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung cancer 3 | 4,466
non-small cell lung cancer 3 | 2,798
psoriasis 3 | 6,685
Breast cancer 2 | 3,094
Chronic Lymphocytic Leukemia 2 | 242
Nijmegen breakage syndrome 2 | 23
Peripheral Neuropathy 2 | 303
Waldenstrons macroglobulinemia 2 | 765
dermatomyositis 2 | 933
glioblastoma 2 | 5,572
invasive ductal carcinoma 2 | 2,950
posterior fossa group A ependymoma 2 | 1,511
tuberculosis and treatment for 6 months 2 | 686
Aplastic anemia 1 | 18
Atopic dermatitis 1 | 944
Bacillary angiomatosis 1 | 7
Bloom syndrome 1 | 30
CUTANEOUS TELANGIECTASIA AND CANCER SYNDROME, FAMILIAL 1 | 1
Carcinoma 1 | 2,147
Cerebrovascular disease 1 | 231
Chloracne 1 | 32
DNA ligase IV deficiency 1 | 6
Dengue disease 1 | 19
Endometriosis 1 | 535
Fanconi's anemia 1 | 50
IGA Glomerulonephritis 1 | 454
Intellectual disability 1 | 573
Israeli tick typhus 1 | 2
Liver Cirrhosis 1 | 101
MHC class II deficiency 1 | 2
Mammary Neoplasms 1 | 410
Mantle cell lymphoma 1 | 18
Meier-Gorlin syndrome 1 | 12
Microcephaly 1 | 149
Neoplasms, Second Primary 1 | 6
Pick disease 1 | 1,893
Pneumoconiosis 1 | 14
Polyploidy 1 | 3
Typhoid fever 1 | 22
Urologic Neoplasms 1 | 7
Xeroderma pigmentosum 1 | 41
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
astrocytic glioma 1 | 2,241
astrocytoma 1 | 1,493
atypical teratoid / rhabdoid tumor 1 | 4,369
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis 1 | 1,665
diabetes mellitus 1 | 1,663
ductal carcinoma in situ 1 | 1,745
esophageal adenocarcinoma 1 | 737
glioblastoma multiforme 1 | 347
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
juvenile dermatomyositis 1 | 1,189
lung adenocarcinoma 1 | 2,713
medulloblastoma, large-cell 1 | 6,234
nasopharyngeal carcinoma 1 | 1,056
non primary Sjogren syndrome sicca 1 | 840
pancreatic cancer 1 | 2,300
pediatric high grade glioma 1 | 2,712
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,031
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 9 | 17,995
Cardiovascular System 9 | 17,958
Digestive Tract 9 | 18,473
Endocrine System 9 | 18,512
Female tissues 9 | 18,647
Liver and Pancreas 9 | 18,136
Male tissues 9 | 17,969
Nervous System 9 | 18,561
Respiratory system 9 | 17,484
Skin and soft tissues 9 | 18,115
Urinary Tract 9 | 18,444

Target Family

Non-IDG 6 | 11,971
Kinase 2 | 634
Enzyme 1 | 4,146

WikiPathways Pathway

ATR Signaling 9 | 9
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cell cycle checkpoint control protein RAD9B RAD9B Tdark Non-IDG -0.05859 1.38 29
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.76182 513.9 350
Cell cycle checkpoint control protein RAD9A RAD9A Tbio Non-IDG -2.13903 136.3 864
Replication protein A 70 kDa DNA-binding subunit RPA1 Tchem Non-IDG -2.45272 281.9 299
ATR-interacting protein ATRIP Tbio Non-IDG -1.57423 40.9 328
Serine/threonine-protein kinase Chk1 CHEK1 Tchem Kinase -2.99378 1014.6 1310
DNA topoisomerase 2-binding protein 1 TOPBP1 Tbio Enzyme -1.99217 107.8 212
Checkpoint protein HUS1 HUS1 Tbio Non-IDG -1.86001 66.4 154
Cell cycle checkpoint protein RAD1 RAD1 Tchem Non-IDG -1.99891 98.1 211