Development Level

Tbio 10 | 10,625
Tchem 4 | 1,890
Tclin 1 | 602

IMPC Phenotype

decreased circulating glucose ... 2 | 121
increased circulating sodium l... 2 | 71
preweaning lethality, complete... 2 | 633
abnormal coat appearance 1 | 25
abnormal motor coordination- b... 1 | 4
decreased bone mineral content 1 | 157
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased urine creatinine lev... 1 | 2
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
increased fasted circulating g... 1 | 68

Disease

ovarian cancer 9 | 8,491
psoriasis 9 | 6,685
glioblastoma 5 | 5,572
osteosarcoma 5 | 7,933
pilocytic astrocytoma 5 | 3,086
lung cancer 4 | 4,473
pituitary cancer 4 | 1,972
posterior fossa group A ependymoma 4 | 1,511
Breast cancer 3 | 3,098
adult high grade glioma 3 | 2,148
aldosterone-producing adenoma 3 | 664
atypical teratoid / rhabdoid tumor 3 | 4,369
colon cancer 3 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
invasive ductal carcinoma 3 | 2,950
lung carcinoma 3 | 2,844
medulloblastoma, large-cell 3 | 6,234
pancreatic cancer 3 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pediatric high grade glioma 3 | 2,712
Alzheimer's disease 2 | 644
Anhidrosis 2 | 12
Bipolar Disorder 2 | 266
Cancer 2 | 2,346
Congenital Nonbullous Ichthyosiform Erythroderma 2 | 9
Congenital ichthyosiform erythroderma 2 | 27
Congenital non-bullous ichthyosiform erythroderma 2 | 7
Ectropion 2 | 18
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Hereditary sensory neuropathy 2 | 6
ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL, NONBULLOUS, 1 2 | 3
Ichthyosis, Congenital, Autosomal Recessive 2 2 | 3
Multiple myeloma 2 | 1,327
Neuropathy 2 | 210
Niemann-Pick disease 2 | 11
Peripheral Neuropathy 2 | 303
Self-healing collodion baby 2 | 3
acute myeloid leukemia 2 | 785
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
astrocytic glioma 2 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 2,254
group 4 medulloblastoma 2 | 1,875
interstitial cystitis 2 | 2,299
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,714
non-small cell lung cancer 2 | 2,798
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 788
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis 2 | 1,563
urothelial carcinoma 2 | 318
Amyotrophic Lateral Sclerosis 1 | 432
Aortic valve insufficiency 1 | 22
Atopic dermatitis 1 | 944
Axonal neuropathy 1 | 17
Dentinogenesis imperfecta 1 | 24
Down syndrome 1 | 548
Duchenne muscular dystrophy 1 | 602
Gaucher's disease 1 | 25
IGA Glomerulonephritis 1 | 454
Ichthyosis vulgaris 1 | 15
Leukemia 1 | 88
Lipid storage disease 1 | 7
Liver disease 1 | 219
Liver diseases 1 | 66
Lymphoma, Follicular 1 | 20
MYELODYSPLASTIC SYNDROME 1 | 39
Multiple Sclerosis 1 | 498
Myocardial Ischemia 1 | 169
Neurodegenerative disease 1 | 383
Neurotic disorder 1 | 9
Osteogenesis imperfecta 1 | 34
Plummer's disease 1 | 7
Prostatic Neoplasms 1 | 471
Tinea corporis 1 | 25
X-linked cerebral adrenoleukodystrophy 1 | 115
astrocytoma 1 | 1,493
atypical teratoid/rhabdoid tumor 1 | 1,095
chronic lymphosyte leukemia 1 | 232
cystic fibrosis 1 | 1,670
diabetes mellitus 1 | 1,663
ependymoma 1 | 2,514
facioscapulohumeral dystrophy 1 | 286
fibroadenoma 1 | 557
glioblastoma multiforme 1 | 347
hepatocellular carcinoma 1 | 550
hereditary spastic paraplegia 1 | 313
interstitial lung disease 1 | 292
medulloblastoma 1 | 1,524
mucosa-associated lymphoid tissue lymphoma 1 | 480
non diabetic and post-ischemic heart failure 1 | 200
oligodendroglioma 1 | 2,849
spina bifida 1 | 1,064
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 15 | 17,994
Cardiovascular System 15 | 17,957
Digestive Tract 15 | 18,472
Endocrine System 15 | 18,511
Female tissues 15 | 18,646
Liver and Pancreas 15 | 18,135
Male tissues 15 | 17,968
Nervous System 15 | 18,560
Respiratory system 15 | 17,483
Skin and soft tissues 15 | 18,114
Urinary Tract 15 | 18,443

Target Family

Enzyme 14 | 4,146
Transcription Factor 1 | 1,400

UniProt Pathway

Lipid metabolism; sphingolipid... 15 | 15
Protein modification; protein ... 381 | 381
Protein modification; protein ... 144 | 144
Glycolipid biosynthesis; glyco... 22 | 22
Protein modification; protein ... 17 | 17
Lipid metabolism; fatty acid b... 15 | 15
Lipid metabolism; fatty acid b... 13 | 13
Cofactor biosynthesis; ubiquin... 11 | 11
Glycan metabolism; heparan sul... 11 | 11
Carbohydrate biosynthesis; glu... 10 | 10
Purine metabolism; 3',5'-cycli... 9 | 9
Cofactor metabolism; retinol m... 8 | 8
Lipid metabolism; phospholipid... 7 | 7
One-carbon metabolism; tetrahy... 7 | 7
Protein modification; peptidyl... 7 | 7
Lipid metabolism; fatty acid m... 6 | 6
Lipid metabolism; polyunsatura... 6 | 6
Phospholipid metabolism; CDP-d... 6 | 6
Sulfur metabolism; glutathione... 6 | 6
tRNA modification; wybutosine-... 6 | 6
Carbohydrate metabolism; hexos... 5 | 5
Cofactor biosynthesis; molybdo... 5 | 5
Fermentation; pyruvate ferment... 5 | 5
Glycan biosynthesis; glycogen ... 5 | 5
Glycan metabolism; heparin bio... 5 | 5
Glycerolipid metabolism; triac... 5 | 5
Lipid metabolism; hydroperoxy ... 5 | 5
Lipid metabolism; mitochondria... 5 | 5
Alcohol metabolism; ethanol de... 4 | 4
Amino-sugar metabolism; N-acet... 4 | 4
Carbohydrate degradation; glyc... 4 | 4
Carbohydrate metabolism; trica... 4 | 4
Cofactor biosynthesis; coenzym... 4 | 4
Glycan metabolism; chondroitin... 4 | 4
Glycerolipid metabolism; triac... 4 | 4
Lipid metabolism; prostaglandi... 4 | 4
Lipid metabolism; steroid bios... 4 | 4
Phospholipid metabolism; CDP-d... 4 | 4
Phospholipid metabolism; phosp... 4 | 4
Polyol metabolism; glycerol de... 4 | 4
Protein modification; protein ... 4 | 4
Steroid biosynthesis; choleste... 4 | 4
Steroid biosynthesis; estrogen... 4 | 4
tRNA modification; 5-methoxyca... 4 | 4
Amine and polyamine biosynthes... 3 | 3
Amino-acid biosynthesis; L-hom... 3 | 3
Amino-acid biosynthesis; L-pro... 3 | 3
Amino-acid biosynthesis; S-ade... 3 | 3
Amino-acid degradation; L-tryp... 3 | 3
Amino-acid degradation; L-vali... 3 | 3
Carbohydrate degradation; glyc... 3 | 3
Carbohydrate degradation; glyc... 3 | 3
Carbohydrate metabolism; galac... 3 | 3
Cofactor biosynthesis; NAD(+) ... 3 | 3
Cofactor biosynthesis; NAD(+) ... 3 | 3
Genetic information processing... 3 | 3
Glycan biosynthesis; glycogen ... 3 | 3
Glycan biosynthesis; hyalurona... 3 | 3
Hormone biosynthesis; thyroid ... 3 | 3
Lipid metabolism; bile acid bi... 3 | 3
Metabolic intermediate biosynt... 3 | 3
Phospholipid metabolism; CDP-d... 3 | 3
Phospholipid metabolism; phosp... 3 | 3
Polyol metabolism; myo-inosito... 3 | 3
Protein modification; carbohyd... 3 | 3
Purine metabolism; 3',5'-cycli... 3 | 3
Purine metabolism; IMP biosynt... 3 | 3
Pyrimidine metabolism; CTP bio... 3 | 3
Pyrimidine metabolism; UMP bio... 3 | 3
Signal transduction; phosphati... 3 | 3
Amino-acid biosynthesis; L-cys... 2 | 2
Amino-acid biosynthesis; beta-... 2 | 2
Amino-acid degradation; L-alan... 2 | 2
Amino-acid degradation; L-leuc... 2 | 2
Amino-acid degradation; L-prol... 2 | 2
Aminoacyl-tRNA biosynthesis; s... 2 | 2
Aromatic compound metabolism; ... 2 | 2
Carbohydrate degradation; glyc... 2 | 2
Carbohydrate degradation; glyc... 2 | 2
Cofactor biosynthesis; adenosy... 2 | 2
Cofactor biosynthesis; iron-su... 2 | 2
Cofactor degradation; phylloqu... 2 | 2
Glycan metabolism; N-glycan me... 2 | 2
Isoprenoid biosynthesis; dimet... 2 | 2
Isoprenoid biosynthesis; farne... 2 | 2
Isoprenoid biosynthesis; geran... 2 | 2
Ketone metabolism; succinyl-Co... 2 | 2
Lipid metabolism; glycerolipid... 2 | 2
Nitrogen metabolism; urea cycl... 2 | 2
Nucleotide-sugar biosynthesis;... 2 | 2
Phospholipid metabolism; phosp... 2 | 2
Phospholipid metabolism; phosp... 2 | 2
Phospholipid metabolism; phosp... 2 | 2
Phospholipid metabolism; phosp... 2 | 2
Pigment biosynthesis; melanin ... 2 | 2
Porphyrin-containing compound ... 2 | 2
Purine metabolism; XMP biosynt... 2 | 2
Pyrimidine metabolism; dTTP bi... 2 | 2
Sulfur metabolism; sulfate ass... 2 | 2
tRNA modification; tRNA-queuos... 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ceramide synthase 5 CERS5 Tbio Transcription Factor -1.28892 17.6 143
Sphingosine-1-phosphate lyase 1 SGPL1 Tchem Enzyme -2.02204 102.8 120
Arachidonate 12-lipoxygenase, 12R-type ALOX12B Tbio Enzyme -1.34255 22.4 63
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase ST8SIA1 Tbio Enzyme -1.49526 33.7 34
Serine palmitoyltransferase small subunit B SPTSSB Tbio Enzyme -1.53877 33.6 0
3-ketodihydrosphingosine reductase KDSR Tbio Enzyme -1.14440 12.5 96
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.67761 46.3 182
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.15284 141.0 260
Serine palmitoyltransferase small subunit A SPTSSA Tbio Enzyme -0.30821 1.95 0
Hydroperoxide isomerase ALOXE3 ALOXE3 Tbio Enzyme -1.49528 28.4 105