Development Level

Tbio 21 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 1 | 220
abnormal sleep behavior 1 | 70
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
impaired righting response 1 | 26
increased body length 1 | 32
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134

Disease

Carcinoma 12 | 11,493
ovarian cancer 11 | 8,520
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
psoriasis 6 | 6,694
glioblastoma 5 | 5,792
Breast cancer 4 | 3,578
diabetes mellitus 4 | 1,728
malignant mesothelioma 4 | 3,232
sonic hedgehog group medulloblastoma 4 | 467
Anemia 3 | 365
Multiple myeloma 3 | 1,332
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
medulloblastoma, large-cell 3 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Abnormality of the urinary system 2 | 21
Acquired metabolic disease 2 | 336
Anemia, Diamond-Blackfan 2 | 16
Anemia, Macrocytic 2 | 18
Autosomal recessive predisposition 2 | 1,442
Bowen-Conradi syndrome 2 | 16
Breast Neoplasms 2 | 445
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cleft Palate 2 | 271
Conduction disorder of the heart 2 | 79
Delayed Puberty 2 | 97
Diamond-Blackfan anemia 2 | 31
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Fatigue 2 | 182
Hand deformities 2 | 32
Hypoplastic mandible condyle 2 | 275
Intermittent migraine headaches 2 | 68
Large intestine cancer 2 | 126
Mammary Neoplasms 2 | 425
Mandibular hypoplasia 2 | 275
Mean cell volume increased 2 | 5
Micrognathism 2 | 275
Migraine Disorders 2 | 76
Pallor 2 | 40
Schizophrenia 2 | 1,160
Turner syndrome 2 | 28
Uranostaphyloschisis 2 | 167
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
genital abnormal 2 | 17
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
reproductive system abnormality 2 | 17
Abnormal urinary amino-acid findings 1 | 38
Acanthosis Nigricans 1 | 27
Aminoaciduria 1 | 38
Autosomal recessive Robinow syndrome 1 | 27
Azoospermia 1 | 110
CSF lactate increased 1 | 33
Death in early childhood 1 | 82
Death in infancy 1 | 82
Decreased liver function 1 | 24
Flexion contracture of proximal interphalangeal joint 1 | 75
Global developmental delay, severe 1 | 47
Gonadoblastoma 1 | 34
HIV Infections 1 | 102
Hemangioma 1 | 69
Hyperplasia of nose 1 | 23
Hypertrophic Cardiomyopathy 1 | 117
Hypertrophy of nose 1 | 23
Increased hepatocellular lipid droplets 1 | 7
Increased intramyocellular lipid droplets 1 | 13
Increased serum lactate 1 | 60
Joint stiffness 1 | 84
Large nose 1 | 23
Liver dysfunction, mild 1 | 24
Parkinson Disease 1 | 64
Respiratory distress 1 | 43
Sensorineural Hearing Loss (disorder) 1 | 284
Sertoli cell-only syndrome 1 | 37
Severe psychomotor retardation 1 | 47
Small for gestational age (disorder) 1 | 69
Spermatogenic Failure, Nonobstructive, Y-Linked 1 | 15
Systemic lupus erythematosus 1 | 194
Vertical Talus 1 | 25
Weight Gain 1 | 100
X-linked cerebral adrenoleukodystrophy 1 | 116
Xeroderma pigmentosum group B 1 | 20
fascioscapulohumeral muscular dystrophy 1 | 100
inflammatory breast cancer 1 | 286
interstitial lung disease 1 | 298
limb girdle muscular dystrophy 2B 1 | 40

Tissue

Blood and immune system 25 | 16,909
Endocrine System 25 | 18,159
Male tissues 25 | 17,142
Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Nervous System 24 | 16,725
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678

Target Family

Non-IDG 17 | 12,091
Enzyme 7 | 4,145
Epigenetic 1 | 242

UniProt Keyword

rRNA-binding 25 | 25
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysine-specific demethylase 2B KDM2B Tchem Epigenetic -1.56328 41.7 248
40S ribosomal protein S18 RPS18 Tbio Non-IDG -1.70681 45.8 128
Ribosomal RNA small subunit methyltransferase NEP1 EMG1 Tbio Enzyme 0.00000 119
40S ribosomal protein S9 RPS9 Tbio Non-IDG -1.42730 26.0 178
60S ribosomal protein L5 RPL5 Tbio Non-IDG -2.02831 78.3 228
5-methylcytosine rRNA methyltransferase NSUN4 NSUN4 Tbio Enzyme -0.32614 1.39 45
40S ribosomal protein S4, Y isoform 2 RPS4Y2 Tdark Non-IDG -0.09339 1.36 23
FAST kinase domain-containing protein 5, mitochondrial FASTKD5 Tdark Enzyme 0.49 0.33 40
Probable ATP-dependent RNA helicase DDX28 DDX28 Tbio Enzyme -0.61805 4.54 109
28S ribosomal protein S17, mitochondrial MRPS17 Tbio Non-IDG 0.44 0.00000 28