Development Level

Tbio 56 | 10,625
Tdark 28 | 7,003
Tchem 2 | 1,890

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to o... 4 | 148
preweaning lethality, incomple... 4 | 260
embryonic lethality prior to t... 3 | 187
abnormal lens morphology 2 | 73
decreased body length 2 | 108
increased circulating chloride... 2 | 43
increased fasted circulating g... 2 | 68
increased mean corpuscular vol... 2 | 91
abnormal behavior 1 | 226
abnormal coat/hair pigmentatio... 1 | 54
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
cataract 1 | 26
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
enlarged heart 1 | 111
hyperactivity 1 | 108
increased KLRG1-positive CD4-p... 1 | 2
increased KLRG1-positive NK ce... 1 | 9
increased NK cell number 1 | 19
increased circulating sodium l... 1 | 71
increased granulocyte number 1 | 8
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 47 | 8,484
osteosarcoma 37 | 7,933
lung cancer 31 | 4,466
medulloblastoma, large-cell 28 | 6,234
group 3 medulloblastoma 25 | 2,254
psoriasis 25 | 6,685
glioblastoma 19 | 5,572
Multiple myeloma 18 | 1,327
malignant mesothelioma 15 | 3,162
colon cancer 12 | 1,475
pediatric high grade glioma 12 | 2,712
Waldenstrons macroglobulinemia 10 | 765
acute quadriplegic myopathy 9 | 1,157
atypical teratoid / rhabdoid tumor 9 | 4,369
diabetes mellitus 9 | 1,663
invasive ductal carcinoma 9 | 2,950
non primary Sjogren syndrome sicca 8 | 840
non-small cell lung cancer 8 | 2,798
subependymal giant cell astrocytoma 8 | 2,287
Cancer 7 | 2,346
Carcinoma 7 | 2,147
primitive neuroectodermal tumor 7 | 3,031
Bowen-Conradi syndrome 6 | 16
Breast cancer 6 | 3,094
dermatomyositis 6 | 933
ependymoma 6 | 2,514
pilocytic astrocytoma 6 | 3,086
Dyskeratosis congenita 5 | 24
Stomach Neoplasms 5 | 282
adult high grade glioma 5 | 2,148
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung adenocarcinoma 5 | 2,713
Disease Progression 4 | 125
Intellectual disability 4 | 573
Rheumatoid Arthritis 4 | 1,160
adrenocortical carcinoma 4 | 1,427
astrocytic glioma 4 | 2,241
astrocytoma 4 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
oligodendroglioma 4 | 2,849
pancreatic cancer 4 | 2,300
pituitary cancer 4 | 1,972
sonic hedgehog group medulloblastoma 4 | 1,482
Mammary Neoplasms 3 | 410
Obesity 3 | 616
Systemic scleroderma 3 | 66
Vascular disease 3 | 281
active Crohn's disease 3 | 918
atypical teratoid/rhabdoid tumor 3 | 1,095
cutaneous lupus erythematosus 3 | 1,056
ductal carcinoma in situ 3 | 1,745
juvenile dermatomyositis 3 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Anemia 2 | 252
Autoimmune Diseases 2 | 33
Brain Neoplasms 2 | 23
Breast abscess 2 | 5
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 1 2 | 3
Dyskeratosis Congenita, Autosomal Recessive 2 | 2
Fatty liver disease 2 | 84
Gastric antral vascular ectasia 2 | 11
Glaucoma 2 | 134
HIV Infections 2 | 100
Hepatitis 2 | 61
Hepatitis C 2 | 90
Idiopathic pulmonary fibrosis 2 | 21
Liver Cirrhosis 2 | 101
Liver neoplasms 2 | 109
Myositis 2 | 24
Neurodegenerative disease 2 | 383
Peripheral Neuropathy 2 | 303
Pick disease 2 | 1,893
Pontocerebellar Hypoplasia Type 1 2 | 5
Pontocerebellar hypoplasia 2 | 29
Supravalvular aortic stenosis 2 | 6
Williams-Beuren syndrome 2 | 45
Wolf-Hirschhorn syndrome 2 | 32
X-linked cerebral adrenoleukodystrophy 2 | 115
acute myeloid leukemia 2 | 780
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 430
gastric carcinoma 2 | 832
group 4 medulloblastoma 2 | 1,875
hepatocellular carcinoma 2 | 532
interleukin-7 receptor alpha deficiency 2 | 16
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
posterior fossa group A ependymoma 2 | 1,511
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 789
Adenocarcinoma Of Esophagus 1 | 14
Genitourinary Neoplasms 1 | 3
Heart Diseases 1 | 42
LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3 1 | 20
LI-FRAUMENI SYNDROME 1 1 | 2
Li-Fraumeni Syndrome 1 | 13
Thymoma 1 | 16
Upper respiratory tract disease 1 | 7
Vulvar Lichen Sclerosus 1 | 2

Tissue

Blood and immune system 86 | 17,995
Cardiovascular System 86 | 17,958
Digestive Tract 85 | 18,473
Endocrine System 85 | 18,512
Female tissues 85 | 18,647
Liver and Pancreas 85 | 18,136
Male tissues 85 | 17,969
Nervous System 85 | 18,561
Urinary Tract 85 | 18,444
Respiratory system 84 | 17,484
Skin and soft tissues 84 | 18,115

Target Family

Non-IDG 50 | 11,971
Enzyme 33 | 4,146
Epigenetic 3 | 242

UniProt Keyword

rRNA processing 86 | 86
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U3 small nucleolar RNA-interacting protein 2 RRP9 Tbio Non-IDG -0.95790 8.59 56
U3 small nucleolar RNA-associated protein 6 homolog UTP6 Tbio Non-IDG -1.00948 10.4 87
rRNA 2'-O-methyltransferase fibrillarin FBL Tbio Enzyme -3.17750 1580.2 240
WD repeat-containing protein 36 WDR36 Tbio Non-IDG -1.67379 47.1 24
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase NOP2 Tbio Enzyme -1.48238 28.2 66
Eukaryotic initiation factor 4A-III EIF4A3 Tbio Non-IDG -2.21804 176.4 137
RNA cytidine acetyltransferase NAT10 Tbio Enzyme -1.77567 65.3 116
Non-canonical poly(A) RNA polymerase PAPD5 PAPD5 Tdark Enzyme -0.66756 3.45 104
Probable ATP-dependent RNA helicase DDX56 DDX56 Tbio Enzyme -0.74504 5.47 166
Exosome component 10 EXOSC10 Tbio Non-IDG -2.41526 265.3 118