Development Level

Tbio 89 | 11,445
Tdark 21 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 16 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased circulating lipase l... 1 | 3
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
hypoactivity 1 | 132
increased mean corpuscular hem... 1 | 96

Disease

Carcinoma 73 | 11,493
ovarian cancer 60 | 8,520
osteosarcoma 53 | 7,950
medulloblastoma, large-cell 49 | 6,241
group 3 medulloblastoma 46 | 4,104
lung cancer 44 | 4,740
atypical teratoid / rhabdoid tumor 35 | 5,112
glioblastoma 35 | 5,792
psoriasis 29 | 6,694
ependymoma 26 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
primitive neuroectodermal tumor 25 | 3,035
Breast cancer 23 | 3,578
malignant mesothelioma 23 | 3,232
oligodendroglioma 22 | 2,850
Kidney cancer 21 | 2,613
astrocytic glioma 20 | 2,597
acute quadriplegic myopathy 19 | 1,158
non-small cell lung cancer 19 | 2,890
Multiple myeloma 18 | 1,332
dermatomyositis 18 | 966
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
adult high grade glioma 17 | 3,801
Cancer 16 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Pick disease 15 | 1,894
Waldenstrons macroglobulinemia 14 | 765
Astrocytoma, Pilocytic 13 | 3,081
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
astrocytoma 12 | 1,146
subependymal giant cell astrocytoma 12 | 2,287
invasive ductal carcinoma 11 | 2,951
lung carcinoma 11 | 2,843
pancreatic cancer 11 | 2,398
Intellectual disability 9 | 1,016
colon cancer 9 | 1,478
lung adenocarcinoma 9 | 2,716
Amyotrophic lateral sclerosis 8 | 451
juvenile dermatomyositis 8 | 1,187
nasopharyngeal carcinoma 8 | 1,058
pediatric high grade glioma 8 | 1,064
tuberculosis 8 | 2,010
Autosomal recessive predisposition 7 | 1,442
Rheumatoid arthritis 7 | 1,191
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
group 4 medulloblastoma 7 | 1,855
spina bifida 7 | 1,074
Gaucher disease type 1 6 | 180
aldosterone-producing adenoma 6 | 665
progressive supranuclear palsy 6 | 676
ulcerative colitis 6 | 1,819
Liver Cirrhosis, Experimental 5 | 769
Schizophrenia 5 | 1,160
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
gastric cancer 5 | 459
hereditary spastic paraplegia 5 | 318
medulloblastoma 5 | 720
Atopic dermatitis 4 | 952
Cognitive delay 4 | 608
Global developmental delay 4 | 608
HIV Infections 4 | 102
Influenza 4 | 142
Mental and motor retardation 4 | 608
Multiple Sclerosis 4 | 540
Short stature 4 | 531
acute myeloid leukemia 4 | 783
cutaneous lupus erythematosus 4 | 1,057
interstitial cystitis 4 | 2,312
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
tuberculosis and treatment for 6 months 4 | 409
Bipolar Disorder 3 | 666
Depressive disorder 3 | 409
Down syndrome 3 | 499
Dull intelligence 3 | 645
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Microcephaly 3 | 166
Neurodegenerative disease 3 | 414
Neurogenic Muscular Atrophy 3 | 139
Pediatric failure to thrive 3 | 365
Polycystic ovary syndrome 3 | 360
Poor school performance 3 | 645
Seizures 3 | 596
Skeletal muscle atrophy 3 | 139
active ulcerative colitis 3 | 764
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
mucosa-associated lymphoid tissue lymphoma 3 | 484
muscle degeneration 3 | 139
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 416
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 100 | 18,159
Blood and immune system 99 | 16,909
Digestive Tract 99 | 17,369
Female tissues 99 | 17,400
Male tissues 99 | 17,142
Respiratory system 99 | 16,393
Liver and Pancreas 98 | 16,750
Nervous System 98 | 16,725
Urinary Tract 98 | 16,678
Skin and soft tissues 97 | 17,230
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 98 | 12,091
Enzyme 12 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

UniProt Keyword

mRNA transport 112 | 112
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
Insulin-like growth factor 2 mRNA-binding protein 2 IGF2BP2 Tbio Non-IDG -1.77792 57.3 400
THO complex subunit 7 homolog THOC7 Tbio Non-IDG -0.34772 2.04 61
THO complex subunit 5 homolog THOC5 Tbio Non-IDG -1.14189 16.8 116
Putative nuclear envelope pore membrane protein POM 121B POM121B Tdark Non-IDG 0.27 0.57 0
ATP-dependent RNA helicase DDX25 DDX25 Tbio Enzyme -1.23468 21.8 47
Transcription elongation factor SPT6 SUPT6H Tbio Non-IDG -1.80696 66.9 123
THO complex subunit 6 homolog THOC6 Tbio Non-IDG -1.77416 57.9 131
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80