Development Level

Tbio 242 | 10,625
Tdark 65 | 7,003
Tchem 19 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 23 | 633
embryonic lethality prior to o... 10 | 148
embryonic lethality prior to t... 9 | 187
abnormal behavior 4 | 226
preweaning lethality, incomple... 4 | 260
decreased grip strength 3 | 123
hyperactivity 3 | 108
increased fasted circulating g... 3 | 68
increased or absent threshold ... 3 | 128
abnormal bone structure 2 | 131
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
decreased body length 2 | 108
decreased leukocyte cell numbe... 2 | 54
decreased neutrophil cell numb... 2 | 37
enlarged heart 2 | 111
increased circulating HDL chol... 2 | 63
increased grip strength 2 | 83
increased mean corpuscular hem... 2 | 93
thrombocytosis 2 | 23
abnormal clavicle morphology 1 | 5
abnormal embryo turning 1 | 15
abnormal esophagus morphology 1 | 4
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal pancreas morphology 1 | 6
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal outer nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal vocalization 1 | 21
absent pinna reflex 1 | 21
absent startle reflex 1 | 15
aorta dilation 1 | 3
cardiovascular system phenotyp... 1 | 35
decreased CD5-positive gamma-d... 1 | 3
decreased IgG2b level 1 | 1
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased bone mineral content 1 | 157
decreased cervical vertebrae n... 1 | 12
decreased circulating alkaline... 1 | 41
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased heart left ventricle... 1 | 2
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased memory-marker CD4-ne... 1 | 4
decreased monocyte cell number 1 | 28
embryonic growth retardation 1 | 28
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased CD4-negative NK T ce... 1 | 4
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
pale yolk sac 1 | 12
pallor 1 | 13
prenatal lethality prior to he... 1 | 64
sparse hair 1 | 6

Disease

ovarian cancer 212 | 8,484
osteosarcoma 165 | 7,933
medulloblastoma, large-cell 115 | 6,234
psoriasis 106 | 6,685
glioblastoma 96 | 5,572
lung cancer 94 | 4,466
group 3 medulloblastoma 86 | 2,254
ependymoma 72 | 2,514
atypical teratoid / rhabdoid tumor 71 | 4,369
oligodendroglioma 70 | 2,849
Multiple myeloma 66 | 1,327
primitive neuroectodermal tumor 66 | 3,031
acute quadriplegic myopathy 61 | 1,157
malignant mesothelioma 54 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 53 | 2,988
Pick disease 48 | 1,893
astrocytoma 48 | 1,493
Breast cancer 47 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,956
astrocytic glioma 44 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,289
dermatomyositis 42 | 933
pediatric high grade glioma 42 | 2,712
Waldenstrons macroglobulinemia 40 | 765
juvenile dermatomyositis 39 | 1,189
diabetes mellitus 38 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,795
non-small cell lung cancer 36 | 2,798
adult high grade glioma 35 | 2,148
lung adenocarcinoma 33 | 2,713
subependymal giant cell astrocytoma 33 | 2,287
Carcinoma 30 | 2,147
pilocytic astrocytoma 30 | 3,086
atypical teratoid/rhabdoid tumor 29 | 1,095
invasive ductal carcinoma 29 | 2,950
progressive supranuclear palsy 29 | 674
group 4 medulloblastoma 27 | 1,875
sonic hedgehog group medulloblastoma 26 | 1,482
pancreatic cancer 25 | 2,300
acute myeloid leukemia 23 | 780
Cancer 22 | 2,346
Intellectual disability 21 | 573
pituitary cancer 21 | 1,972
tuberculosis and treatment for 6 months 20 | 686
Amyotrophic Lateral Sclerosis 18 | 431
Rheumatoid Arthritis 18 | 1,160
non primary Sjogren syndrome sicca 17 | 840
breast carcinoma 16 | 1,614
colon cancer 16 | 1,475
Muscular atrophy 15 | 67
Gaucher disease type 1 14 | 171
aldosterone-producing adenoma 14 | 664
hepatocellular carcinoma 14 | 532
lung carcinoma 14 | 2,844
nasopharyngeal carcinoma 14 | 1,056
posterior fossa group A ependymoma 14 | 1,511
medulloblastoma 13 | 1,524
spina bifida 13 | 1,064
posterior fossa group B ependymoma 12 | 1,530
primary pancreatic ductal adenocarcinoma 12 | 1,271
Neurodegenerative disease 11 | 383
Spinal muscular atrophy 11 | 24
adrenocortical carcinoma 11 | 1,427
cystic fibrosis 11 | 1,665
Alzheimer's disease 10 | 644
primary Sjogren syndrome 10 | 789
Duchenne muscular dystrophy 9 | 602
Microcephaly 9 | 149
Polycystic Ovary Syndrome 9 | 332
Schizophrenia 9 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
ductal carcinoma in situ 9 | 1,745
Down syndrome 8 | 548
HIV Infections 8 | 100
gastric cancer 8 | 430
hereditary spastic paraplegia 8 | 313
pancreatic carcinoma 8 | 567
tuberculosis 8 | 1,557
ulcerative colitis 8 | 2,087
Retinitis pigmentosa 7 | 153
Atopic dermatitis 6 | 944
Epilepsy 6 | 346
IGA Glomerulonephritis 6 | 454
Melanoma 6 | 261
Myotonic dystrophy type 1 6 | 16
Stomach Neoplasms 6 | 282
gastric carcinoma 6 | 832
interstitial cystitis 6 | 2,299
relapsing-remitting multiple sclerosis 6 | 18
Azoospermia 5 | 89
Frontotemporal dementia 5 | 41
Lupus erythematosus 5 | 80
Mammary Neoplasms 5 | 410
Pontocerebellar hypoplasia 5 | 29
Subcutaneous panniculitis-like T-cell lymphoma 5 | 16
glioblastoma multiforme 5 | 347
interstitial lung disease 5 | 291
tuberculosis and treatment for 3 months 5 | 327
cutaneous lupus erythematosus 4 | 1,056
mucosa-associated lymphoid tissue lymphoma 4 | 480

Tissue

Female tissues 324 | 18,647
Male tissues 323 | 17,969
Blood and immune system 322 | 17,995
Endocrine System 321 | 18,512
Digestive Tract 318 | 18,473
Urinary Tract 318 | 18,444
Cardiovascular System 316 | 17,958
Liver and Pancreas 316 | 18,136
Nervous System 316 | 18,561
Respiratory system 316 | 17,484
Skin and soft tissues 313 | 18,115

Target Family

Non-IDG 256 | 11,971
Enzyme 55 | 4,146
Kinase 6 | 634
Epigenetic 5 | 242
Transcription Factor 4 | 1,400

UniProt Keyword

mRNA processing 326 | 326
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear cap-binding protein subunit 3 NCBP3 Tbio Non-IDG -1.68208 49.3 22
CUGBP Elav-like family member 4 CELF4 Tbio Non-IDG -1.46075 29.8 40
Small nuclear ribonucleoprotein F SNRPF Tdark Non-IDG -0.25254 1.81 65
Small nuclear ribonucleoprotein G SNRPG Tdark Non-IDG 1.33 95
Serine/arginine repetitive matrix protein 2 SRRM2 Tbio Non-IDG -1.90106 71.6 51
Small nuclear ribonucleoprotein E SNRPE Tbio Non-IDG -2.70963 540.8 230
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
PHD finger-like domain-containing protein 5A PHF5A Tbio Epigenetic -1.94489 96.2 127
Pre-mRNA-splicing factor 38A PRPF38A Tdark Non-IDG -0.69167 4.80 72
SURP and G-patch domain-containing protein 1 SUGP1 Tbio Non-IDG -2.08366 122.0 109