Development Level

Tclin 14 | 602
Tchem 5 | 1,890
Tbio 2 | 10,625

IMPC Term

abnormal behavior 1 | 226
abnormal lens morphology 1 | 73
abnormal whole-body plethysmog... 1 | 4
decreased body temperature 1 | 2
decreased body weight 1 | 174
decreased circulating amylase ... 1 | 24
decreased circulating triglyce... 1 | 83
enlarged heart 1 | 111
hypoactivity 1 | 89
increased blood uric acid leve... 1 | 5
increased cellular hemoglobin ... 1 | 2
increased circulating potassiu... 1 | 31
increased mean corpuscular vol... 1 | 91
macrophthalmia 1 | 2
preweaning lethality, incomple... 1 | 260

Disease

Atrial Fibrillation 15 | 110
Chronic heart failure 15 | 46
Myocardial Perfusion Imaging Adjunct 15 | 25
Platelet Aggregation Inhibition 15 | 22
Prevention of Cerebral Thrombosis 15 | 29
medulloblastoma, large-cell 10 | 6,234
invasive ductal carcinoma 8 | 2,950
Breast cancer 7 | 3,094
malignant mesothelioma 7 | 3,162
osteosarcoma 7 | 7,933
ovarian cancer 7 | 8,484
Impotence 6 | 45
atypical teratoid / rhabdoid tumor 6 | 4,369
breast carcinoma 6 | 1,614
colon cancer 6 | 1,475
lung adenocarcinoma 6 | 2,713
oligodendroglioma 6 | 2,849
pituitary cancer 6 | 1,972
Blindness 5 | 84
Carcinoma 5 | 2,147
Fundus dystrophy 5 | 77
Retinitis pigmentosa 5 | 153
group 4 medulloblastoma 5 | 1,875
interstitial cystitis 5 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung cancer 5 | 4,466
psoriasis 5 | 6,685
ulcerative colitis 5 | 2,087
Achromatopsia 4 | 14
Pick disease 4 | 1,893
Retinal Degeneration 4 | 49
ductal carcinoma in situ 4 | 1,745
glioblastoma 4 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
lung carcinoma 4 | 2,844
pilocytic astrocytoma 4 | 3,086
posterior fossa group B ependymoma 4 | 1,530
primitive neuroectodermal tumor 4 | 3,031
Night Blindness 3 | 39
Pulmonary hypertension 3 | 52
astrocytic glioma 3 | 2,241
cutaneous lupus erythematosus 3 | 1,056
fibroadenoma 3 | 557
non-small cell lung cancer 3 | 2,798
non-small cell lung carcinoma 3 | 413
pediatric high grade glioma 3 | 2,712
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
Acquired metabolic disease 2 | 267
Acute heart failure 2 | 2
Amphetamine-Related Disorders 2 | 74
Asthma 2 | 349
Benign prostatic hyperplasia 2 | 7
Cone dystrophy 2 | 57
Congenital nystagmus 2 | 26
Leber congenital amaurosis 2 | 72
Progressive cone dystrophy (without rod involvement) 2 | 4
Rheumatoid Arthritis 2 | 1,160
active Crohn's disease 2 | 918
adult high grade glioma 2 | 2,148
cystic fibrosis 2 | 1,665
diabetes mellitus 2 | 1,663
ependymoma 2 | 2,514
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
progressive supranuclear palsy 2 | 674
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,557
Age related macular degeneration 1 | 84
Anterior ischemic optic neuropathy 1 | 7
Aortic aneurysm 1 | 34
Asthma management 1 | 20
Bipolar Disorder 1 | 266
Blood pressure finding 1 | 56
Brachydactyly 1 | 52
Brain cancer 1 | 21
Bronchitis 1 | 44
Dyspepsia 1 | 34
Gout 1 | 93
Heart conduction disease 1 | 65
Hypogonadism 1 | 70
Macular degeneration 1 | 41
Major Depressive Disorder 1 | 106
Mammary Neoplasms 1 | 410
Migraine Disorders 1 | 26
Myocardial Infarction 1 | 126
Neoplasm Metastasis 1 | 138
Precancerous Conditions 1 | 69
Premature ejaculation 1 | 16
Primary pigmented nodular adrenocortical disease 1 | 12
Prostatic hypertrophy 1 | 9
Pulmonary emphysema 1 | 34
Secretory diarrhea 1 | 6
Sezary Syndrome 1 | 26
Systemic arterial pressure 1 | 56
Tracheal stenosis 1 | 18
Tularemia 1 | 22
X-linked cerebral adrenoleukodystrophy 1 | 115
active ulcerative colitis 1 | 477
non-inflammatory breast cancer 1 | 208

Tissue

Blood and immune system 21 | 17,995
Cardiovascular System 21 | 17,958
Digestive Tract 21 | 18,473
Endocrine System 21 | 18,512
Female tissues 21 | 18,647
Liver and Pancreas 21 | 18,136
Male tissues 21 | 17,969
Nervous System 21 | 18,561
Respiratory system 21 | 17,484
Skin and soft tissues 21 | 18,115
Urinary Tract 21 | 18,444

Target Family

Enzyme 16 | 4,146
Ion Channel 3 | 341
Kinase 2 | 634

UniProt Keyword

cGMP 21 | 21
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

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