Development Level

Tclin 19 | 612
Tbio 11 | 11,651
Tchem 5 | 1,388
Tdark 1 | 6,593

Collection

Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal bone structure 2 | 187
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 32 | 11,493
medulloblastoma, large-cell 23 | 6,241
atypical teratoid / rhabdoid tumor 22 | 5,112
osteosarcoma 19 | 7,950
glioblastoma 18 | 5,792
Atrial Fibrillation 17 | 124
ovarian cancer 17 | 8,520
Chronic heart failure 16 | 46
astrocytic glioma 16 | 2,597
ependymoma 16 | 4,679
primitive neuroectodermal tumor 15 | 3,035
Astrocytoma, Pilocytic 14 | 3,081
adult high grade glioma 14 | 3,801
oligodendroglioma 14 | 2,850
psoriasis 14 | 6,694
Myocardial Perfusion Imaging Adjunct 13 | 25
Platelet Aggregation Inhibition 13 | 22
Prevention of Cerebral Thrombosis 13 | 29
group 3 medulloblastoma 13 | 4,104
invasive ductal carcinoma 13 | 2,951
Breast cancer 11 | 3,578
lung carcinoma 10 | 2,843
malignant mesothelioma 10 | 3,232
diabetes mellitus 9 | 1,728
Carney complex 8 | 25
Depressive disorder 8 | 409
Dysuria 8 | 26
Increased Urinary Frequency 8 | 11
Nocturia 8 | 9
Pick disease 8 | 1,894
Suprapubic pain 8 | 8
Urgent desire to urinate 8 | 11
Urinary Incontinence 8 | 50
Urinary Tract Irritation 8 | 24
lung adenocarcinoma 8 | 2,716
lung cancer 8 | 4,740
tuberculosis 8 | 2,010
Acrodysostosis 7 | 12
Obesity 7 | 678
ductal carcinoma in situ 7 | 1,745
non-small cell lung cancer 7 | 2,890
ulcerative colitis 7 | 1,819
Asthma 6 | 385
Hypogonadism 6 | 173
Kidney cancer 6 | 2,613
Primary pigmented nodular adrenocortical disease 6 | 13
Short stature 6 | 531
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
COPD Associated with Chronic Bronchitis 5 | 11
Hypertensive disease 5 | 292
Increase in blood pressure 5 | 119
Mental Depression 5 | 333
Schizophrenia 5 | 1,160
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Adrenal hyperplasia 4 | 13
Aphthous ulcer of mouth 4 | 7
Atopic dermatitis 4 | 952
Autistic Disorder 4 | 364
Chronic obstructive pulmonary disease 4 | 184
Cushing's syndrome 4 | 48
Fatigue 4 | 182
Impotence 4 | 46
Increased susceptibility to fractures 4 | 21
Linear atrophy 4 | 15
Muscle Weakness 4 | 170
Neurogenic Muscular Atrophy 4 | 139
Neurogenic muscle atrophy, especially in the lower limbs 4 | 139
Osteoporosis 4 | 363
Paroxysmal atrial fibrillation 4 | 14
Pigmented micronodular adrenocortical disease 4 | 4
Severe chronic obstructive pulmonary disease 4 | 4
Skeletal muscle atrophy 4 | 139
Slender build 4 | 14
Thin skin 4 | 47
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
medulloblastoma 4 | 720
muscle degeneration 4 | 139
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
subependymal giant cell astrocytoma 4 | 2,287
Anteverted nostril 3 | 191
Bipolar Disorder 3 | 666
Broad flat nasal bridge 3 | 236
Down syndrome 3 | 499
Nasal bridge wide 3 | 236
Short metacarpal 3 | 43
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
cutaneous lupus erythematosus 3 | 1,057
fibroadenoma 3 | 559
pancreatic carcinoma 3 | 562
progressive supranuclear palsy 3 | 676

Tissue

Endocrine System 36 | 18,159
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Digestive Tract 33 | 17,369
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Blood and immune system 32 | 16,909
Cardiovascular System 32 | 15,192
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Urinary Tract 32 | 16,678

Target Family

Enzyme 20 | 4,145
Ion Channel 7 | 344
Non-IDG 5 | 12,091
Kinase 4 | 634

UniProt Keyword

cAMP 36 | 36
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

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