Development Level

Tbio 18 | 11,445
Tdark 9 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal urinary bladder morph... 1 | 11
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
male infertility 1 | 123
microphthalmia 1 | 26
small superior vagus ganglion 1 | 74

Disease

Williams-Beuren syndrome 24 | 50
osteosarcoma 12 | 7,950
Carcinoma 11 | 11,493
psoriasis 11 | 6,694
Kidney Failure 10 | 111
Supravalvular aortic stenosis 10 | 12
Angle class 2 malocclusion 9 | 57
Angle class 3 malocclusion 9 | 57
Attention deficit hyperactivity disorder 9 | 278
Autistic Disorder 9 | 364
Blepharophimosis 9 | 70
Bunion 9 | 26
Congenital Epicanthus 9 | 177
Constipation 9 | 181
Decreased size of teeth 9 | 62
Decreased width of tooth 9 | 59
Dull intelligence 9 | 645
Dyschezia 9 | 135
Full lower lip 9 | 64
Gait imbalance 9 | 17
Hallux Valgus 9 | 26
Hoarseness 9 | 31
Hyperacusis 9 | 11
Hyperreflexia 9 | 209
Hypodontia 9 | 81
Intellectual disability 9 | 1,016
Long philtrum 9 | 137
Low intelligence 9 | 645
Malocclusion 9 | 57
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Microdontia (disorder) 9 | 59
Mitral Valve Prolapse Syndrome 9 | 39
Mitral regurgitation, mild 9 | 32
Mitral valve insufficiency 9 | 49
Muscle hypotonia 9 | 571
Obesity 9 | 678
Pelvic kidney 9 | 10
Peripheral pulmonary artery stenosis 9 | 14
Phonophobia 9 | 11
Poor school performance 9 | 645
Prominent lower lip 9 | 64
Pulmonary Stenosis 9 | 45
Renal Insufficiency 9 | 90
Renal failure in adulthood 9 | 76
Sensorineural Hearing Loss (disorder) 9 | 284
Short nose 9 | 132
Short stature 9 | 531
Sloping shoulders 9 | 21
Small nose 9 | 132
Strabismus 9 | 270
Williams Syndrome 9 | 10
Abdominal Pain 8 | 98
Abnormality of pelvic girdle bone morphology 8 | 37
Abnormality of the fingernails 8 | 51
Anxiety 8 | 136
Anxiety disease 8 | 113
Arthralgia 8 | 90
Broad forehead 8 | 59
Cellulitis of periorbital region 8 | 13
Cerebellar Dysmetria 8 | 56
Chronic otitis media 8 | 52
Coarse facial features 8 | 108
Colon diverticulum anatomic structure 8 | 15
Congenital anomaly of neck 8 | 19
Deformity of neck 8 | 19
Diverticular disease of colon 8 | 15
Dysgraphia 8 | 20
Extrapyramidal Disorders 8 | 29
Extrapyramidal sign 8 | 29
Flatfoot 8 | 73
Hernia, Inguinal 8 | 89
High forehead 8 | 102
High-grade hypermetropia 8 | 24
Hypercalcemia 8 | 59
Hypercalciuria 8 | 27
Hypertension, Renovascular 8 | 10
Joint stiffness 8 | 84
Knee joint valgus deformity 8 | 56
Kyphosis deformity of spine 8 | 114
Large auricle 8 | 87
Large dysplastic ears 8 | 87
Large pinnae 8 | 87
Large prominent ears 8 | 87
Large protruding ears 8 | 87
Large, floppy ears 8 | 87
Lordosis 8 | 54
Macrotia 8 | 87
Malformation of the neck 8 | 19
Nausea and vomiting 8 | 97
Periorbital edema 8 | 13
Pointed chin 8 | 33
Prominent ear 8 | 56
Protruding ears 8 | 56
Tall forehead 8 | 102
Thickened facial skin with coarse facial features 8 | 108
Tremor 8 | 113
Visual Impairment 8 | 174
ear infection chronic 8 | 52
obsessive-compulsive disorder 8 | 61

Tissue

Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Blood and immune system 26 | 16,909
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Cardiovascular System 25 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 7 | 4,145
Transcription Factor 5 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

UniProt Keyword

Williams-Beuren syndrome 29 | 29
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase BAZ1B BAZ1B Tbio Epigenetic -1.45627 32.0 155
General transcription factor II-I repeat domain-containing protein 2A GTF2IRD2 Tbio Transcription Factor -0.45484 3.02 58
Putative NOL1/NOP2/Sun domain family member 5B NSUN5P1 Tdark Enzyme 0.00000 0
General transcription factor II-I repeat domain-containing protein 1 GTF2IRD1 Tbio Transcription Factor -1.74692 0.00000 281
Elastin ELN Tbio Non-IDG -3.36288 2144.5 299
Putative methyltransferase NSUN5C NSUN5P2 Tdark Enzyme 0.00000 0
Transducin beta-like protein 2 TBL2 Tbio Non-IDG -1.00878 10.8 139
Claudin-3 CLDN3 Tbio Non-IDG -2.37681 227.3 358
Replication factor C subunit 2 RFC2 Tbio Non-IDG -1.36589 20.3 293
Protein ABHD11 ABHD11 Tbio Enzyme -0.85496 5.74 96