Development Level

Tbio 5 | 11,445
Tclin 2 | 613

IMPC Phenotype

embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
preweaning lethality, incomple... 1 | 499
small spleen 1 | 19

Disease

Carcinoma 7 | 11,493
Sensorineural Hearing Loss (disorder) 7 | 284
Waardenburg's syndrome 7 | 17
Heterochromia iridis 6 | 9
Premature canities 6 | 24
White forelock 6 | 12
blue iris (physical finding) 6 | 17
hypopigmented skin patch 6 | 59
Autosomal recessive predisposition 5 | 1,442
Blonde eyebrow 5 | 5
Broad flat nasal bridge 5 | 236
Deafness 5 | 198
Grey eyebrow 5 | 5
Grey eyelashes 5 | 5
Hirschsprung Disease 5 | 31
Hirschsprung's disease 5 | 46
Megacolon 5 | 29
Nasal bridge wide 5 | 236
Piebaldism 5 | 15
Retinal depigmentation 5 | 12
Sensorineural hearing loss 5 | 106
Synophrys 5 | 40
Thin hypoplastic alae nasi 5 | 51
Tietz syndrome 5 | 6
White eyebrows 5 | 5
White eyelashes 5 | 5
Abnormality of vision 4 | 40
Cancer 4 | 2,499
Congenital deafness 4 | 185
Convex nasal bridge 4 | 57
Hearing Loss, Partial 4 | 185
Melanoma 4 | 711
Microphthalmia 4 | 76
Nystagmus 4 | 317
Prominent nasal bridge 4 | 57
Small head 4 | 374
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
hearing impairment 4 | 199
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
ulcerative colitis 4 | 1,819
Abdominal Pain 3 | 98
Achromasia 3 | 11
Albinism 3 | 11
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Congenital sensorineural hearing loss 3 | 12
Constipation 3 | 181
Disorder of macula of retina 3 | 6
Dyschezia 3 | 135
Intestinal Obstruction 3 | 31
Kidney cancer 3 | 2,613
Olfactory lobe absence 3 | 6
Sarcoma 3 | 62
Telecanthus 3 | 62
WAARDENBURG SYNDROME, TYPE 4A 3 | 3
Waardenburg Syndrome Type 2 3 | 4
Waardenburg-Shah syndrome 3 | 3
breast carcinoma 3 | 1,638
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
psoriasis 3 | 6,694
Breast Neoplasms 2 | 445
Down syndrome 2 | 499
Downward slant of palpebral fissure 2 | 158
Freckles 2 | 33
Heart disease 2 | 306
Highly variable severity 2 | 157
Hyperopia 2 | 70
Hypertension 2 | 396
Hypopigmentation disorder 2 | 25
Low Vision 2 | 174
Mammary Neoplasms 2 | 425
Melanocytic nevus 2 | 43
Nausea and vomiting 2 | 97
Neoplasm Invasiveness 2 | 161
Oculocutaneous albinism 2 | 29
Optic nerve dysplasia 2 | 6
Paraparesis, Spastic 2 | 16
Peripheral Neuropathy 2 | 134
Photodysphoria 2 | 121
Photophobia 2 | 121
Reduced visual acuity 2 | 63
Senile lentigo 2 | 10
Skin cancer 2 | 469
Strabismus 2 | 270
Variable expressivity 2 | 157
Vestibular hypofunction 2 | 7
Visual Impairment 2 | 174
Vitiligo 2 | 73
Weight decreased 2 | 103
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
cystic fibrosis and chronic rhinosinusitis 2 | 214
fibroadenoma 2 | 559
medulloblastoma 2 | 720
nephrosclerosis 2 | 333

Tissue

Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Skin and soft tissues 7 | 17,230
Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192
Respiratory system 5 | 16,393

Target Family

Transcription Factor 4 | 1,400
Enzyme 1 | 4,145
GPCR 1 | 408
Non-IDG 1 | 12,091

UniProt Keyword

Waardenburg syndrome 7 | 7
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosinase TYR Tclin Enzyme -3.32888 2021.2 494
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Endothelin-3 EDN3 Tbio Non-IDG -2.96371 794.0 219
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Endothelin receptor type B EDNRB Tclin GPCR -3.27771 1756.7 324
Paired box protein Pax-3 PAX3 Tbio Transcription Factor -2.83871 692.1 400
Microphthalmia-associated transcription factor MITF Tbio Transcription Factor -3.09082 1244.1 549