Development Level

Tbio 179 | 10,625
Tdark 89 | 7,003
Tchem 10 | 1,890

IMPC Term

preweaning lethality, complete... 17 | 633
embryonic lethality prior to t... 7 | 187
increased mean corpuscular vol... 6 | 91
increased grip strength 5 | 83
preweaning lethality, incomple... 5 | 260
decreased body weight 4 | 174
decreased bone mineral content 4 | 157
embryonic lethality prior to o... 4 | 148
abnormal bone structure 3 | 131
decreased circulating glucose ... 3 | 121
decreased grip strength 3 | 123
decreased leukocyte cell numbe... 3 | 54
increased bone mineral content 3 | 92
increased circulating alkaline... 3 | 119
prenatal lethality prior to he... 3 | 64
abnormal behavior 2 | 226
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal tooth morphology 2 | 24
decreased B cell number 2 | 30
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased circulating serum al... 2 | 79
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
decreased lumbar vertebrae num... 2 | 62
decreased neutrophil cell numb... 2 | 37
decreased total body fat amoun... 2 | 186
fusion of vertebral arches 2 | 7
hyperactivity 2 | 108
increased mean corpuscular hem... 2 | 93
increased mean platelet volume 2 | 19
increased sacral vertebrae num... 2 | 62
prenatal lethality 2 | 16
straub tail 2 | 26
thrombocytopenia 2 | 46
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 52
abnormal eye morphology 1 | 38
abnormal heart left ventricle ... 1 | 20
abnormal iris morphology 1 | 12
abnormal lumbar vertebrae morp... 1 | 6
abnormal pelvic girdle bone mo... 1 | 11
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent heartbeat 1 | 6
absent lymph nodes 1 | 3
absent pinna reflex 1 | 21
anophthalmia 1 | 20
decreased KLRG1+ CD4 alpha bet... 1 | 2
decreased NK cell number 1 | 16
decreased anxiety-related resp... 1 | 12
decreased basophil cell number 1 | 11
decreased circulating chloride... 1 | 32
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased eosinophil cell numb... 1 | 41
decreased heart rate 1 | 10
decreased hematocrit 1 | 25
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
edema 1 | 11
embryonic growth retardation 1 | 28
female infertility 1 | 34
hemorrhage 1 | 12
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased CD4-positive, CD25-p... 1 | 18
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating calcium ... 1 | 32
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased granulocyte number 1 | 8
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased red blood cell distr... 1 | 21
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
oligodactyly 1 | 14
pale yolk sac 1 | 12
short tibia 1 | 82

Disease

ovarian cancer 155 | 8,484
osteosarcoma 137 | 7,933
medulloblastoma, large-cell 103 | 6,234
psoriasis 102 | 6,685
glioblastoma 89 | 5,572
atypical teratoid / rhabdoid tumor 69 | 4,369
group 3 medulloblastoma 58 | 2,254
lung cancer 57 | 4,466
malignant mesothelioma 51 | 3,162
Carcinoma 49 | 2,147
ependymoma 43 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,956
pediatric high grade glioma 41 | 2,712
Breast cancer 40 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,289
primitive neuroectodermal tumor 39 | 3,031
oligodendroglioma 38 | 2,849
Pick disease 36 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,988
lung carcinoma 34 | 2,844
subependymal giant cell astrocytoma 34 | 2,287
astrocytic glioma 32 | 2,241
adult high grade glioma 31 | 2,148
invasive ductal carcinoma 30 | 2,950
lung adenocarcinoma 30 | 2,713
pilocytic astrocytoma 30 | 3,086
posterior fossa group B ependymoma 30 | 1,530
acute quadriplegic myopathy 29 | 1,157
non-small cell lung cancer 27 | 2,798
pituitary cancer 23 | 1,972
colon cancer 21 | 1,475
diabetes mellitus 21 | 1,663
pancreatic cancer 21 | 2,300
Multiple myeloma 20 | 1,327
adrenocortical carcinoma 20 | 1,427
astrocytoma 20 | 1,493
group 4 medulloblastoma 20 | 1,875
interstitial cystitis 20 | 2,299
medulloblastoma 20 | 1,524
nasopharyngeal carcinoma 20 | 1,056
Rheumatoid Arthritis 19 | 1,160
dermatomyositis 17 | 933
sonic hedgehog group medulloblastoma 17 | 1,482
tuberculosis 17 | 1,557
Cancer 16 | 2,346
chronic rhinosinusitis 16 | 512
juvenile dermatomyositis 16 | 1,189
Intellectual disability 15 | 573
progressive supranuclear palsy 15 | 674
tuberculosis and treatment for 6 months 15 | 686
Waldenstrons macroglobulinemia 14 | 765
ductal carcinoma in situ 14 | 1,745
spina bifida 14 | 1,064
breast carcinoma 13 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
primary pancreatic ductal adenocarcinoma 13 | 1,271
ulcerative colitis 13 | 2,087
non primary Sjogren syndrome sicca 12 | 840
acute myeloid leukemia 11 | 780
cystic fibrosis 11 | 1,665
posterior fossa group A ependymoma 11 | 1,511
atypical teratoid/rhabdoid tumor 10 | 1,095
gastric carcinoma 10 | 832
Alzheimer's disease 9 | 644
cutaneous lupus erythematosus 9 | 1,056
Asphyxiating thoracic dystrophy 8 | 32
Atopic dermatitis 8 | 944
Ciliopathy 8 | 57
Polydactyly 8 | 93
hepatocellular carcinoma 8 | 532
pancreatic carcinoma 8 | 567
Amyotrophic Lateral Sclerosis 7 | 431
Neurodegenerative disease 7 | 383
Obesity 7 | 616
Sensenbrenner syndrome 7 | 15
active Crohn's disease 7 | 918
non-small cell lung carcinoma 7 | 413
primary Sjogren syndrome 7 | 789
tuberculosis and treatment for 3 months 7 | 327
Endometriosis 6 | 535
IGA Glomerulonephritis 6 | 454
Jeune thoracic dystrophy 6 | 9
Schizophrenia 6 | 501
aldosterone-producing adenoma 6 | 664
esophageal adenocarcinoma 6 | 737
gastric cancer 6 | 430
Chediak-Higashi syndrome 5 | 24
Crohn's disease 5 | 304
Disease Progression 5 | 125
Down syndrome 5 | 548
Duchenne muscular dystrophy 5 | 602
Gaucher disease type 1 5 | 171
Microcephaly 5 | 149
Retinitis pigmentosa 5 | 153
Stomach Neoplasms 5 | 282
cystic fibrosis and chronic rhinosinusitis 5 | 213
sarcoidosis 5 | 358
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
chronic lymphosyte leukemia 4 | 232
mucosa-associated lymphoid tissue lymphoma 4 | 480

Tissue

Blood and immune system 278 | 17,995
Digestive Tract 278 | 18,473
Endocrine System 278 | 18,512
Female tissues 278 | 18,647
Male tissues 278 | 17,969
Nervous System 278 | 18,561
Cardiovascular System 277 | 17,958
Liver and Pancreas 277 | 18,136
Urinary Tract 277 | 18,444
Skin and soft tissues 276 | 18,115
Respiratory system 273 | 17,484

Target Family

Non-IDG 248 | 11,971
Enzyme 23 | 4,146
Epigenetic 3 | 242
Kinase 2 | 634
Transcription Factor 2 | 1,400

UniProt Keyword

WD repeat 278 | 278
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WD repeat-containing protein 87 WDR87 Tdark Non-IDG 0.42 0.25 12
Striatin STRN Tbio Non-IDG -1.63637 51.0 118
U3 small nucleolar RNA-interacting protein 2 RRP9 Tbio Non-IDG -0.95790 8.59 56
Protein TSSC1 TSSC1 Tbio Non-IDG -0.63572 4.60 119
WD repeat-containing protein 63 WDR63 Tdark Non-IDG -0.73038 5.69 23
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform PPP2R2A Tchem Enzyme -1.29353 14.5 115
WD repeat-containing protein 75 WDR75 Tdark Non-IDG -0.40457 2.42 13
Cilia- and flagella-associated protein 43 CFAP43 Tdark Non-IDG 0.00000 0
WD repeat and FYVE domain-containing protein 1 WDFY1 Tbio Non-IDG -0.67020 4.80 91
Tectonin beta-propeller repeat-containing protein 2 TECPR2 Tdark Non-IDG -0.62839 4.84 6